Sodium in PDB 4h6s: Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A

All present enzymatic activity of Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A:
3.4.21.5;

The structure of Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A, PDB code: 4h6s was solved by N.Pozzi, Z.Chen, F.Zapata, L.A.Pelc, E.Di Cera, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.13 / 2.19
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	63.904, 70.828, 56.103, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 25.9

The binding sites of Sodium atom in the Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A (pdb code 4h6s). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A, PDB code: 4h6s:

Sodium binding site 1 out of 1 in the Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Thrombin Mutant E14EA/D14LA/E18A/S195A within 5.0Å range: probe atom residue distance (Å) B Occ B:Na301 b:27.7 occ:1.00 O B:HOH473 2.4 35.2 1.0 O B:HOH457 2.4 42.0 1.0 O B:LYS224 2.4 30.9 1.0 O B:HOH405 2.4 28.4 1.0 O B:ARG221A 2.5 34.8 1.0 O B:HOH401 2.6 33.9 1.0 C B:ARG221A 3.4 35.3 1.0 N B:ARG221A 3.4 34.2 1.0 C B:LYS224 3.5 30.3 1.0 O B:HOH459 3.6 32.4 1.0 O B:HOH408 3.8 37.2 1.0 C B:ASP221 3.9 33.2 1.0 CA B:ARG221A 4.1 35.4 1.0 N B:LYS224 4.1 31.4 1.0 O B:TYR184A 4.1 32.0 1.0 O B:HOH461 4.1 33.6 1.0 CA B:ASP221 4.2 32.3 1.0 CA B:LYS224 4.2 31.0 1.0 N B:ASP222 4.3 35.3 1.0 O B:HOH488 4.5 39.8 1.0 N B:TYR225 4.5 29.1 1.0 O B:ASP221 4.5 33.7 1.0 OD1 B:ASP221 4.6 29.9 1.0 N B:GLY223 4.6 33.5 1.0 CB B:LYS224 4.6 30.7 1.0 CA B:ASP222 4.6 35.4 1.0 CA B:TYR225 4.8 28.4 1.0 C B:ASP222 4.8 34.5 1.0 N B:ASP221 4.9 31.8 1.0 CD1 B:TYR225 4.9 25.6 1.0 O B:HOH441 4.9 33.7 1.0

N.Pozzi, Z.Chen, F.Zapata, W.Niu, S.Barranco-Medina, L.A.Pelc, E.Di Cera. Autoactivation of Thrombin Precursors. J.Biol.Chem. V. 288 11601 2013.
ISSN: ISSN 0021-9258
PubMed: 23467412
DOI: 10.1074/JBC.M113.451542