Sodium in PDB 4u3z: Apo MAP4K4 T181E Phosphomimetic Mutant

All present enzymatic activity of Apo MAP4K4 T181E Phosphomimetic Mutant:
2.7.11.1;

The structure of Apo MAP4K4 T181E Phosphomimetic Mutant, PDB code: 4u3z was solved by S.F.Harris, P.Wu, M.Coons, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.41 / 2.09
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	79.720, 80.900, 92.570, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 24.9

The binding sites of Sodium atom in the Apo MAP4K4 T181E Phosphomimetic Mutant (pdb code 4u3z). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Apo MAP4K4 T181E Phosphomimetic Mutant, PDB code: 4u3z:

Sodium binding site 1 out of 1 in the Apo MAP4K4 T181E Phosphomimetic Mutant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Apo MAP4K4 T181E Phosphomimetic Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Na403 b:42.9 occ:1.00 OG1 A:THR84 2.6 28.6 1.0 O A:HIS79 2.6 28.7 1.0 O A:ILE82 2.7 27.8 1.0 O A:SER77 2.8 40.7 1.0 O A:HOH701 2.9 54.2 1.0 O A:HIS78 3.2 45.3 1.0 C A:HIS78 3.4 40.1 1.0 OE1 A:GLU106 3.4 47.8 1.0 C A:HIS79 3.5 31.7 1.0 N A:THR84 3.7 36.8 1.0 CB A:THR84 3.8 37.7 1.0 CA A:HIS78 3.8 42.2 1.0 C A:ILE82 3.8 31.9 1.0 C A:SER77 3.8 40.5 1.0 NZ A:LYS168 3.9 42.8 1.0 N A:HIS79 3.9 37.3 1.0 CA A:THR84 4.0 32.4 1.0 CA A:ARG80 4.2 36.7 1.0 N A:ARG80 4.2 30.5 1.0 N A:HIS78 4.3 37.8 1.0 CA A:HIS79 4.4 31.4 1.0 CG2 A:THR84 4.4 34.4 1.0 N A:ILE82 4.4 28.8 1.0 C A:ARG80 4.4 37.7 1.0 C A:ALA83 4.4 33.0 1.0 O A:ARG80 4.5 35.7 1.0 CD A:GLU106 4.6 45.4 1.0 CA A:ILE82 4.6 32.1 1.0 CA A:ALA83 4.8 36.0 1.0 N A:ALA83 4.8 31.5 1.0 CB A:ILE82 4.9 35.1 1.0 O A:HOH540 4.9 46.0 1.0

P.Wu, H.Chen, M.Coons, T.D.Crawford, D.S.Kirkpatrick, L.Murray, C.O.Ndubaku, J.Nonomiya, V.Pham, S.Schmidt, T.Smysczek, P.Vitorino, W.Ye, S.F.Harris. Structural Plasticity and Kinase Activation in A Cohort of MAP4K4 Structures To Be Published.