Sodium in PDB 3epi: Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp

All present enzymatic activity of Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp:
2.7.7.7;

The structure of Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp, PDB code: 3epi was solved by M.G.Pence, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.99 / 2.90
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	98.643, 98.643, 202.231, 90.00, 90.00, 120.00
R / Rfree (%)	23.6 / 28.2

The binding sites of Sodium atom in the Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp (pdb code 3epi). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp, PDB code: 3epi:

Sodium binding site 1 out of 1 in the Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of Human Dna Polymerase Iota Complexed with N2-Ethylguanine and Incoming Ttp within 5.0Å range: probe atom residue distance (Å) B Occ A:Na421 b:15.9 occ:1.00 OP1 B:DC12 2.3 11.2 1.0 O A:ILE242 2.4 19.6 1.0 O A:LYS237 2.7 14.7 1.0 O A:ILE239 2.9 14.9 1.0 C A:ILE239 3.5 14.8 1.0 C A:ILE242 3.5 19.7 1.0 P B:DC12 3.6 11.7 1.0 C A:LYS237 3.6 14.1 1.0 CA A:PRO240 3.9 16.1 1.0 N A:PRO240 4.0 15.4 1.0 OP2 B:DC12 4.0 10.8 1.0 N A:ILE239 4.2 13.7 1.0 C A:GLU238 4.2 13.5 1.0 N A:GLY241 4.3 17.7 1.0 N A:ILE242 4.3 19.3 1.0 N A:GLY243 4.4 20.4 1.0 CA A:GLY243 4.4 21.4 1.0 N A:GLU238 4.4 14.0 1.0 CA A:LYS237 4.4 13.9 1.0 CA A:ILE242 4.4 19.4 1.0 CA A:ILE239 4.5 14.0 1.0 CA A:GLU238 4.5 13.4 1.0 O3' B:DC11 4.5 11.5 1.0 C A:PRO240 4.6 17.1 1.0 O A:GLU238 4.6 13.6 1.0 O5' B:DC12 4.7 10.6 1.0 O A:ILE236 4.8 13.2 1.0 NZ A:LYS237 4.8 19.4 1.0 CD A:LYS237 5.0 19.1 1.0

M.G.Pence, P.Blans, C.N.Zink, T.Hollis, J.C.Fishbein, F.W.Perrino. Lesion Bypass of N2-Ethylguanine By Human Dna Polymerase Iota. J.Biol.Chem. V. 284 1732 2009.
ISSN: ISSN 0021-9258
PubMed: 18984581
DOI: 10.1074/JBC.M807296200