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Sodium in PDB 9lnq: The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du

Enzymatic activity of The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du

All present enzymatic activity of The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du:
3.2.2.27;

Protein crystallography data

The structure of The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du, PDB code: 9lnq was solved by Y.Liu, C.Zhou, X.Zhan, C.Fan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.74 / 1.74
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 48.86, 65.339, 98.979, 90, 90, 90
R / Rfree (%) 19.2 / 22.5

Sodium Binding Sites:

The binding sites of Sodium atom in the The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du (pdb code 9lnq). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du, PDB code: 9lnq:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in 9lnq

Go back to Sodium Binding Sites List in 9lnq
Sodium binding site 1 out of 3 in the The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na101

b:30.0
occ:1.00
O4 A:KBC5 2.2 20.0 1.0
H E:TYR147 2.4 26.6 1.0
HA E:PRO146 2.6 19.9 1.0
H E:PHE158 2.9 25.3 1.0
C4 A:KBC5 3.0 20.0 1.0
O E:HOH588 3.0 30.1 1.0
O E:HOH531 3.0 30.4 1.0
HD22 E:ASN204 3.2 25.8 1.0
N E:TYR147 3.2 20.6 1.0
HD2 E:TYR147 3.2 24.4 1.0
C5 A:KBC5 3.3 20.0 1.0
HA E:CYS157 3.3 25.3 1.0
HB3 E:PRO146 3.4 25.6 1.0
CA E:PRO146 3.5 14.7 1.0
HA E:ALA153 3.5 28.0 1.0
CD2 E:TYR147 3.5 19.1 1.0
HB3 E:ALA153 3.6 23.1 1.0
N E:PHE158 3.7 19.2 1.0
HB2 E:ALA153 3.8 23.1 1.0
C E:PRO146 3.9 20.3 1.0
ND2 E:ASN204 3.9 19.2 1.0
CB E:PRO146 3.9 19.6 1.0
HB2 E:TYR147 4.0 24.7 1.0
HD21 E:ASN204 4.0 25.8 1.0
O E:LEU156 4.0 20.6 1.0
CG E:TYR147 4.0 20.8 1.0
CB E:ALA153 4.0 17.9 1.0
CE2 E:TYR147 4.1 18.6 1.0
CA E:CYS157 4.2 19.0 1.0
HE2 E:TYR147 4.2 23.9 1.0
HA E:PHE158 4.2 23.2 1.0
N3 A:KBC5 4.2 20.0 1.0
CA E:ALA153 4.2 22.1 1.0
CB E:TYR147 4.3 19.4 1.0
CA E:TYR147 4.3 16.5 1.0
H E:SER159 4.4 27.2 1.0
C E:CYS157 4.4 17.9 1.0
CA E:PHE158 4.5 17.7 1.0
H E:HIS154 4.5 24.8 1.0
HB2 E:PRO146 4.5 25.6 1.0
O E:ASP145 4.6 21.8 1.0
N E:PRO146 4.6 18.4 1.0
H E:GLY155 4.6 30.4 1.0
C6 A:KBC5 4.7 20.0 1.0
C E:LEU156 4.7 21.9 1.0
O E:SER159 4.7 19.8 1.0
O E:HOH596 4.8 29.9 1.0
HG3 E:PRO146 4.8 25.0 1.0
HA E:TYR147 4.8 21.3 1.0
N E:SER159 4.8 21.2 1.0
N E:CYS157 4.9 18.9 1.0
CD1 E:TYR147 4.9 21.8 1.0
CZ E:TYR147 4.9 23.1 1.0
CG E:PRO146 4.9 18.9 1.0
HB2 E:CYS157 5.0 26.1 1.0
C E:PHE158 5.0 23.2 1.0
HB1 E:ALA153 5.0 23.1 1.0

Sodium binding site 2 out of 3 in 9lnq

Go back to Sodium Binding Sites List in 9lnq
Sodium binding site 2 out of 3 in the The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Na401

b:27.4
occ:0.00
H E:VAL118 2.3 29.9 1.0
O E:HOH503 2.6 34.4 1.0
HH21 E:ARG113 2.6 31.1 1.0
HA E:THR117 3.1 33.6 1.0
HG2 E:ARG113 3.1 37.2 1.0
N E:VAL118 3.2 25.6 1.0
HD3 E:ARG113 3.2 32.2 1.0
HB E:VAL118 3.3 24.1 1.0
HA E:ARG113 3.4 30.5 1.0
NH2 E:ARG113 3.4 26.0 1.0
HB3 E:ARG113 3.5 35.6 1.0
O E:VAL118 3.6 21.8 1.0
HG21 E:THR117 3.6 32.1 1.0
HH22 E:ARG113 3.7 31.1 1.0
CG E:ARG113 3.8 31.9 1.0
O E:HOH504 3.8 32.5 1.0
O E:HOH598 3.8 34.7 1.0
CD E:ARG113 3.9 27.6 1.0
O E:TYR116 3.9 32.2 1.0
CB E:ARG113 3.9 31.1 1.0
CA E:THR117 3.9 29.6 1.0
CA E:VAL118 4.0 21.4 1.0
CB E:VAL118 4.0 20.2 1.0
C E:THR117 4.0 26.9 1.0
CA E:ARG113 4.1 27.1 1.0
C E:VAL118 4.2 24.0 1.0
O E:ARG113 4.4 37.4 1.0
HG23 E:VAL118 4.4 24.8 1.0
CZ E:ARG113 4.5 22.2 1.0
CG2 E:THR117 4.5 28.1 1.0
HD2 E:ARG113 4.6 32.2 1.0
CG2 E:VAL118 4.6 21.1 1.0
HG22 E:VAL118 4.7 24.8 1.0
HG3 E:ARG113 4.7 37.2 1.0
NE E:ARG113 4.7 27.2 1.0
C E:ARG113 4.8 36.9 1.0
CB E:THR117 4.8 26.4 1.0
HD3 E:PRO122 4.8 31.3 1.0
C E:TYR116 4.8 27.3 1.0
HB2 E:ARG113 4.9 35.6 1.0
HA E:VAL118 4.9 25.5 1.0
N E:THR117 4.9 31.3 1.0
HG23 E:THR117 4.9 32.1 1.0

Sodium binding site 3 out of 3 in 9lnq

Go back to Sodium Binding Sites List in 9lnq
Sodium binding site 3 out of 3 in the The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of The Hung Bound to Dna Product Embedding 4PRIMER-OCH3-Du within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Na402

b:30.0
occ:1.00
H E:TYR101 2.5 31.1 1.0
HD2 E:PRO100 2.8 40.6 1.0
HD1 E:TYR101 2.9 25.6 1.0
HB3 E:TYR101 2.9 32.4 1.0
O E:HOH586 3.0 33.3 1.0
HB3 E:LYS99 3.2 26.1 1.0
N E:TYR101 3.3 27.2 1.0
HB2 E:PRO100 3.4 35.7 1.0
CD E:PRO100 3.6 36.3 1.0
CB E:TYR101 3.8 27.6 1.0
CD1 E:TYR101 3.8 21.7 1.0
N E:PRO100 3.8 29.0 1.0
HG2 E:PRO100 4.0 39.2 1.0
CB E:PRO100 4.0 32.3 1.0
HE22 E:GLN224 4.1 34.3 1.0
CG E:PRO100 4.1 35.6 1.0
CB E:LYS99 4.1 23.1 1.0
CA E:TYR101 4.1 28.2 1.0
C E:PRO100 4.2 27.0 1.0
CA E:PRO100 4.2 25.7 1.0
CG E:TYR101 4.3 22.1 1.0
HD3 E:LYS99 4.3 43.9 1.0
C E:LYS99 4.4 32.3 1.0
HD3 E:PRO100 4.4 40.6 1.0
HB2 E:LYS99 4.4 26.1 1.0
HB2 E:TYR101 4.5 32.4 1.0
HA E:TYR101 4.6 32.8 1.0
HA E:LYS99 4.7 28.1 1.0
CA E:LYS99 4.7 25.1 1.0
NE2 E:GLN224 4.7 29.0 1.0
O E:HOH620 4.9 33.4 1.0
CE1 E:TYR101 4.9 25.8 1.0
HB3 E:PRO100 4.9 35.7 1.0
H E:PHE102 4.9 29.1 1.0
HE1 E:TYR101 4.9 30.9 1.0

Reference:

C.Fan, X.Zhan, F.Guo, Q.Li, K.Lu, X.Shan, Y.Zhou, M.Ren, M.M.Greenberg, Y.Liu, C.Zhou. Uridine Embedded Within Dna Is Repaired By Uracil Dna Glycosylase Via A Mechanism Distinct From That of Ribonuclease H2. J.Am.Chem.Soc. V. 147 11574 2025.
ISSN: ESSN 1520-5126
PubMed: 40130361
DOI: 10.1021/JACS.5C01436
Page generated: Mon Aug 18 17:21:58 2025

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