Sodium in PDB 8elk: Hras R97F Crystal Form 1

All present enzymatic activity of Hras R97F Crystal Form 1:
3.6.5.2;

The structure of Hras R97F Crystal Form 1, PDB code: 8elk was solved by C.W.Johnson, C.Mattos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.07 / 1.80
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	88.147, 88.147, 133.27, 90, 90, 120
R / Rfree (%)	17 / 19.5

The structure of Hras R97F Crystal Form 1 also contains other interesting chemical elements:

Calcium	(Ca)	2 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Sodium atom in the Hras R97F Crystal Form 1 (pdb code 8elk). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Hras R97F Crystal Form 1, PDB code: 8elk:

Sodium binding site 1 out of 1 in the Hras R97F Crystal Form 1


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Hras R97F Crystal Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na206 b:23.7 occ:0.50 O A:HOH431 2.4 44.6 0.5 OD2 A:ASP105 2.4 42.0 1.0 O A:ARG102 2.5 40.5 1.0 OD1 A:ASP105 2.8 49.1 1.0 O A:HOH303 2.9 46.8 0.5 CG A:ASP105 2.9 44.8 1.0 C A:ARG102 3.4 39.8 1.0 CA A:VAL103 4.2 36.5 1.0 N A:VAL103 4.2 27.5 1.0 CA A:ARG102 4.3 34.7 1.0 CB A:ASP105 4.3 41.8 1.0 CG A:ARG102 4.4 50.3 1.0 C A:VAL103 4.4 42.5 1.0 O A:HOH317 4.5 42.4 1.0 N A:ASP105 4.5 43.2 1.0 O A:VAL103 4.5 40.9 1.0 CA A:ASP105 4.7 46.5 1.0 NH2 A:ARG73 4.8 47.9 1.0 CB A:ARG102 4.9 44.4 1.0

C.W.Johnson, S.K.Fetics, K.P.Davis, J.A.Rodrigues, C.Mattos. Allosteric Site Variants Affect Gtp Hydrolysis on Ras. Protein Sci. E4767 2023.
ISSN: ESSN 1469-896X
PubMed: 37615343
DOI: 10.1002/PRO.4767