Atomistry » Sodium » PDB 7jyw-7kou » 7kkg
Atomistry »
  Sodium »
    PDB 7jyw-7kou »
      7kkg »

Sodium in PDB 7kkg: Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site

Enzymatic activity of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site

All present enzymatic activity of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site:
4.3.3.7;

Protein crystallography data

The structure of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site, PDB code: 7kkg was solved by S.Saran, M.Majdi Yazdi, D.A.R.Sanders, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.88 / 1.64
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 85.67, 225.73, 200.88, 90, 90, 90
R / Rfree (%) 13.8 / 16.9

Other elements in 7kkg:

The structure of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site also contains other interesting chemical elements:

Magnesium (Mg) 21 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site (pdb code 7kkg). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site, PDB code: 7kkg:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in 7kkg

Go back to Sodium Binding Sites List in 7kkg
Sodium binding site 1 out of 3 in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na302

b:29.2
occ:1.00
O A:HOH684 2.7 17.6 1.0
O A:HOH457 3.2 14.0 1.0
C2 A:EDO306 4.1 14.7 1.0
CB A:GLU160 4.1 18.1 1.0
O2 A:EDO306 4.3 14.3 1.0
O A:HOH481 4.4 20.3 1.0
O A:HOH760 4.5 24.4 1.0
O A:HOH584 4.5 16.6 1.0
O A:HOH609 4.6 17.6 1.0
C1 A:EDO306 4.9 14.8 1.0
CG A:GLU160 4.9 15.2 1.0
O A:HOH798 4.9 32.5 1.0

Sodium binding site 2 out of 3 in 7kkg

Go back to Sodium Binding Sites List in 7kkg
Sodium binding site 2 out of 3 in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na309

b:25.6
occ:1.00
O C:HOH710 2.5 30.3 1.0
O C:HOH644 3.0 30.7 1.0
N C:GLU57 3.0 11.9 1.0
O C:HOH604 3.1 14.4 1.0
CB C:GLU57 3.5 15.4 1.0
N C:HIS56 3.5 10.5 1.0
CB C:THR55 3.5 11.3 1.0
OG1 C:THR55 3.7 11.6 1.0
CA C:GLU57 3.8 11.9 1.0
C C:HIS56 3.9 10.8 1.0
CB C:HIS56 3.9 10.1 1.0
CA C:HIS56 3.9 9.9 1.0
O F:HOH710 4.0 42.0 1.0
C C:THR55 4.2 10.3 1.0
CA C:THR55 4.4 11.4 1.0
OE1 C:GLU57 4.4 54.0 1.0
O C:HOH468 4.5 17.6 1.0
CG2 C:THR55 4.6 12.0 1.0
O C:HOH674 4.6 27.6 1.0
O C:HOH755 4.6 23.8 1.0
CG C:GLU57 4.8 30.4 1.0

Sodium binding site 3 out of 3 in 7kkg

Go back to Sodium Binding Sites List in 7kkg
Sodium binding site 3 out of 3 in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, N84D Mutant with Pyruvate Bound in the Active Site and L-Lysine Bound at the Allosteric Site within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na310

b:26.3
occ:1.00
O B:HOH426 2.6 13.6 1.0
OE1 C:GLU191 2.8 12.5 1.0
O B:HOH626 3.1 12.8 1.0
CD C:GLU191 3.4 18.2 1.0
CA C:GLY170 3.4 13.7 1.0
CD1 C:ILE194 3.6 8.8 1.0
O B:HOH731 3.9 30.0 1.0
OE2 C:GLU191 3.9 21.4 1.0
CG1 C:ILE194 3.9 8.7 1.0
CG2 C:ILE194 3.9 6.7 1.0
CB B:ASP173 4.0 9.6 1.0
N C:GLY170 4.1 10.0 1.0
CB C:GLU191 4.2 10.0 1.0
CG C:GLU191 4.3 12.0 1.0
OD2 B:ASP173 4.4 11.8 1.0
O C:HOH426 4.5 24.3 1.0
C C:GLY170 4.6 18.9 1.0
CB C:ILE194 4.6 6.3 1.0
CG B:ASP173 4.7 7.6 1.0
O C:HOH562 4.8 35.3 1.0
N B:ASP173 4.9 10.0 1.0
CA B:ASP173 4.9 9.7 1.0

Reference:

S.Saran, M.Majdi Yazd, D.R.J.Palmer, D.A.R.Sanders. A Tight Dimer Interface N84 Residue, Plays A Critical Role in the Transmission of the Allosteric Inhibition Signals in Cj.Dhdps To Be Published.
Page generated: Mon Aug 18 10:23:35 2025

Last articles

Mg in 9IUJ
Mg in 9HHY
Mg in 9HRA
Mg in 9I7L
Mg in 9IFP
Mg in 9IFQ
Mg in 9HGQ
Mg in 9IB5
Mg in 9IAY
Mg in 9H9I
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy