Sodium in PDB 9d68: Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State

The binding sites of Sodium atom in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State (pdb code 9d68). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State, PDB code: 9d68:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na602 b:32.4 occ:1.00 O A:ASN366 2.2 39.4 1.0 OD2 A:ASP455 2.5 36.0 1.0 O A:GLY362 2.7 32.2 1.0 O A:ASN451 2.8 33.6 1.0 OD1 A:ASP455 2.8 33.6 1.0 CG A:ASP455 3.0 33.9 1.0 C A:ASN366 3.4 32.0 1.0 CE A:MET367 3.4 39.3 1.0 C A:ASN451 3.4 25.3 1.0 C A:GLY362 3.5 23.8 1.0 CA A:ALA363 3.6 26.5 1.0 CB A:ASN451 3.8 23.6 1.0 N A:ALA363 3.9 26.4 1.0 CA A:ASN451 3.9 25.3 1.0 CB A:ASN366 4.0 28.4 1.0 CA A:ASN366 4.1 30.4 1.0 C A:ALA363 4.2 29.1 1.0 N A:VAL452 4.3 21.1 1.0 O A:ALA363 4.4 33.9 1.0 N A:ASN366 4.5 30.7 1.0 N A:MET367 4.5 34.0 1.0 CB A:ASP455 4.5 29.2 1.0 CB A:SER333 4.5 35.9 1.0 OG A:SER333 4.5 38.5 1.0 CA A:GLY362 4.6 20.6 1.0 CA A:VAL452 4.7 25.0 1.0 CA A:MET367 4.7 28.3 1.0 CG A:ASN451 4.7 25.0 1.0 CG A:ASN366 4.7 33.1 1.0 CB A:ALA363 4.8 22.9 1.0 ND2 A:ASN366 4.8 38.6 1.0 N A:THR364 4.9 28.8 1.0 SD A:MET367 4.9 46.5 1.0 N A:ASP455 5.0 25.4 1.0

Sodium binding site 2 out of 2 in the Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Human Excitatory Amino Acid Transporter 3 (EAAT3) with Bound L- Cysteine in An Outward Facing State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na603 b:40.3 occ:1.00 OD1 A:ASP368 2.1 45.7 1.0 O A:TYR98 2.1 36.0 1.0 OD1 A:ASN366 2.1 33.7 1.0 OG1 A:THR102 2.2 33.6 1.0 OG1 A:THR101 2.5 25.6 1.0 N A:THR102 2.7 32.3 1.0 CG A:ASP368 3.1 38.8 1.0 C A:TYR98 3.1 31.6 1.0 CB A:THR102 3.2 32.4 1.0 CA A:THR102 3.3 32.8 1.0 CG A:ASN366 3.4 33.1 1.0 OD2 A:ASP368 3.4 42.0 1.0 C A:THR101 3.5 29.5 1.0 CB A:THR101 3.5 29.1 1.0 CA A:TYR98 3.5 27.4 1.0 CA A:THR101 3.9 28.9 1.0 N A:THR101 4.1 36.6 1.0 O A:TYR97 4.1 28.9 1.0 ND2 A:ASN366 4.1 38.6 1.0 N A:PHE99 4.3 33.1 1.0 CB A:TYR98 4.3 28.6 1.0 O A:THR101 4.4 34.0 1.0 CB A:ASP368 4.4 34.9 1.0 CA A:ASN366 4.5 30.4 1.0 CB A:ASN366 4.5 28.4 1.0 CG2 A:THR102 4.5 32.6 1.0 N A:ASP368 4.5 36.0 1.0 N A:TYR98 4.7 26.7 1.0 CA A:ASP368 4.7 34.3 1.0 N A:MET367 4.7 34.0 1.0 C A:THR102 4.8 36.7 1.0 C A:PHE99 4.8 34.5 1.0 CG2 A:THR101 4.8 34.9 1.0 C A:TYR97 4.8 26.6 1.0 CA A:PHE99 4.8 29.4 1.0 C A:ASN366 4.9 32.0 1.0 O A:PHE99 4.9 38.1 1.0

B.Qiu, O.Boudker. Structural Basis of the Excitatory Amino Acid Transporter 3 Substrate Recognition. Biorxiv 2024.
ISSN: ISSN 2692-8205
PubMed: 39282329
DOI: 10.1101/2024.09.05.611541