Sodium in PDB 8qch: Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001

The structure of Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001, PDB code: 8qch was solved by C.Zimberger, B.Canard, F.Ferron, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	105.53 / 2.44
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	142.757, 142.983, 156.399, 90, 90, 90
R / Rfree (%)	21.4 / 24.3

The structure of Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001 also contains other interesting chemical elements:

Fluorine	(F)	8 atoms
Zinc	(Zn)	8 atoms

The binding sites of Sodium atom in the Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001 (pdb code 8qch). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001, PDB code: 8qch:

Sodium binding site 1 out of 1 in the Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Human Adenosine Deaminase-Like Protein in Complex with Compound AT8001 within 5.0Å range: probe atom residue distance (Å) B Occ H:Na404 b:54.9 occ:1.00 N H:ILE355 3.3 52.5 1.0 CG1 H:ILE355 3.4 56.5 1.0 ND1 H:HIS354 3.6 56.0 1.0 CB H:HIS354 3.6 50.9 1.0 CA H:HIS354 3.7 49.7 1.0 C H:HIS354 4.0 51.5 1.0 CG H:HIS354 4.0 53.9 1.0 CD1 H:ILE355 4.2 57.6 1.0 CA H:ILE355 4.3 54.4 1.0 CB H:ILE355 4.5 55.4 1.0 CE1 H:HIS354 4.8 56.5 1.0 C H:ILE355 4.8 55.6 1.0 O H:LEU353 4.9 46.8 1.0 N H:HIS354 5.0 47.8 1.0

A.Chazot, C.Zimberger, M.Feracci, A.Moussa, S.Good, J.P.Sommadossi, K.Alvarez, F.Ferron, B.Canard. The Activation Chain of the Broad-Spectrum Antiviral Bemnifosbuvir at Atomic Resolution Plos Biol. 2024.
ISSN: ESSN 1545-7885
DOI: 10.1371/JOURNAL.PBIO.3002743