Sodium in PDB 8ddr: Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2

The binding sites of Sodium atom in the Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2 (pdb code 8ddr). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2, PDB code: 8ddr:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1403 b:15.3 occ:1.00 O C:GLY1056 2.9 17.1 1.0 O D:GLY1056 2.9 18.2 1.0 O B:GLY1056 2.9 15.9 1.0 O A:GLY1056 2.9 17.4 1.0 C C:GLY1056 3.8 17.1 1.0 C D:GLY1056 3.8 18.2 1.0 C B:GLY1056 3.8 15.9 1.0 C A:GLY1056 3.8 17.4 1.0 CA C:GLY1056 4.1 17.1 1.0 CA D:GLY1056 4.1 18.2 1.0 CA B:GLY1056 4.1 15.9 1.0 CA A:GLY1056 4.1 17.4 1.0 NA A:NA1404 4.4 19.9 1.0 N C:GLU1057 4.9 15.8 1.0 N D:GLU1057 4.9 17.3 1.0 N A:GLU1057 4.9 15.1 1.0 N B:GLU1057 4.9 14.7 1.0

Sodium binding site 2 out of 2 in the Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Cryo-Em Structure of TRPM3 Ion Channel in the Absence of PIP2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1404 b:19.9 occ:1.00 CA C:GLY1056 4.2 17.1 1.0 CA D:GLY1056 4.2 18.2 1.0 CA B:GLY1056 4.2 15.9 1.0 CA A:GLY1056 4.2 17.4 1.0 NA A:NA1403 4.4 15.3 1.0 N C:GLY1056 4.9 17.1 1.0 N D:GLY1056 4.9 18.2 1.0 N B:GLY1056 4.9 15.9 1.0 N A:GLY1056 4.9 17.4 1.0

C.Zhao, R.Mackinnon. Structural and Functional Analyses of A Gpcr-Inhibited Ion Channel TRPM3. Neuron 2022.
ISSN: ISSN 0896-6273
PubMed: 36283409
DOI: 10.1016/J.NEURON.2022.10.002