Sodium in PDB 8cv3: Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State

The binding sites of Sodium atom in the Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State (pdb code 8cv3). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State, PDB code: 8cv3:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na601 b:35.5 occ:1.00 O A:ASN366 2.6 38.4 1.0 O A:GLY362 3.3 35.5 1.0 OD2 A:ASP455 3.3 37.3 1.0 CB A:ASN451 3.5 35.8 1.0 CA A:ALA363 3.7 34.8 1.0 O A:ALA363 3.7 38.6 1.0 OD1 A:ASP455 3.7 36.3 1.0 C A:ASN366 3.8 37.6 1.0 CG A:ASP455 3.8 36.3 1.0 O A:ASN451 3.9 36.0 1.0 OG A:SER333 3.9 40.2 1.0 C A:GLY362 4.1 33.2 1.0 C A:ALA363 4.1 36.9 1.0 SD A:MET367 4.1 50.1 1.0 C A:ASN451 4.1 36.4 1.0 CB A:SER333 4.2 39.3 1.0 N A:ALA363 4.3 33.3 1.0 CA A:ASN451 4.3 36.4 1.0 CG A:ASN451 4.4 38.4 1.0 CB A:ASN366 4.5 35.8 1.0 CA A:ASN366 4.5 37.1 1.0 ND2 A:ASN451 4.6 37.9 1.0 N A:ASN366 4.7 37.3 1.0 CB A:ALA363 4.8 33.9 1.0 N A:MET367 4.8 38.1 1.0 N A:VAL452 4.8 36.2 1.0 CA A:MET367 4.9 38.7 1.0

Sodium binding site 2 out of 2 in the Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Human Excitatory Excitatory Amino Acid Transporter 3 (EAAT3) Protomer at in An Intermediate Outward Facing Sodium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na602 b:37.2 occ:1.00 OD1 A:ASP368 2.4 37.5 1.0 OG1 A:THR101 2.4 31.0 1.0 OG1 A:THR102 2.4 33.5 1.0 O A:TYR98 2.4 33.3 1.0 OD1 A:ASN366 2.4 37.0 1.0 N A:THR102 2.6 34.3 1.0 CB A:THR101 3.1 30.8 1.0 C A:THR101 3.2 33.0 1.0 CA A:THR102 3.3 33.2 1.0 CB A:THR102 3.4 32.8 1.0 C A:TYR98 3.4 32.0 1.0 CG A:ASP368 3.5 36.8 1.0 CA A:THR101 3.6 30.5 1.0 CG A:ASN366 3.6 36.6 1.0 CA A:TYR98 3.8 30.2 1.0 OD2 A:ASP368 3.9 35.6 1.0 N A:THR101 4.0 30.5 1.0 O A:THR101 4.1 33.5 1.0 ND2 A:ASN366 4.2 36.1 1.0 CG2 A:THR101 4.5 31.6 1.0 CB A:TYR98 4.5 30.4 1.0 O A:TYR97 4.5 32.2 1.0 CG2 A:THR102 4.6 35.5 1.0 N A:PHE99 4.6 32.0 1.0 CB A:ASP368 4.7 36.9 1.0 C A:THR102 4.7 33.8 1.0 CB A:ASN366 4.8 35.8 1.0 CA A:ASN366 4.9 37.1 1.0 N A:ASP368 4.9 38.6 1.0 N A:MET367 4.9 38.1 1.0 CA A:ASP368 5.0 37.8 1.0 CD1 A:TYR98 5.0 32.5 1.0 C A:PHE99 5.0 30.8 1.0 N A:TYR98 5.0 29.6 1.0

B.Qiu, O.Boudker. Symport and Antiport Mechanisms of Human Glutamate Transporters Nat Commun 2023.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-023-38120-5