Sodium in PDB 8c5d: Glutathione Transferase P1-1 From Mus Musculus
Enzymatic activity of Glutathione Transferase P1-1 From Mus Musculus
All present enzymatic activity of Glutathione Transferase P1-1 From Mus Musculus:
2.5.1.18;
Protein crystallography data
The structure of Glutathione Transferase P1-1 From Mus Musculus, PDB code: 8c5d
was solved by
A.C.Papageorgiou,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
38.68 /
1.28
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
56.617,
77.366,
101.444,
90,
90,
90
|
|
R / Rfree (%)
|
17.5 /
20
|
Other elements in 8c5d:
The structure of Glutathione Transferase P1-1 From Mus Musculus also contains other interesting chemical elements:
Sodium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
11;
Binding sites:
The binding sites of Sodium atom in the Glutathione Transferase P1-1 From Mus Musculus
(pdb code 8c5d). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 11 binding sites of Sodium where determined in the
Glutathione Transferase P1-1 From Mus Musculus, PDB code: 8c5d:
Jump to Sodium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Sodium binding site 1 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 1 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na503
b:23.8
occ:1.00
|
HH11
|
A:ARG100
|
2.1
|
19.4
|
1.0
|
|
HD3
|
A:ARG100
|
2.7
|
18.2
|
1.0
|
|
O
|
A:HOH752
|
2.8
|
18.2
|
1.0
|
|
NH1
|
A:ARG100
|
2.9
|
16.2
|
1.0
|
|
HG3
|
A:ARG100
|
3.0
|
17.8
|
1.0
|
|
CA
|
A:CA509
|
3.2
|
20.6
|
1.0
|
|
HA2
|
A:GLY12
|
3.2
|
17.7
|
1.0
|
|
HH12
|
A:ARG100
|
3.3
|
19.4
|
1.0
|
|
HG22
|
A:VAL104
|
3.4
|
21.1
|
1.0
|
|
HG23
|
A:VAL104
|
3.4
|
21.1
|
1.0
|
|
HG2
|
A:ARG100
|
3.4
|
17.8
|
1.0
|
|
HG3
|
A:ARG13
|
3.4
|
20.6
|
1.0
|
|
CD
|
A:ARG100
|
3.5
|
15.2
|
1.0
|
|
CG
|
A:ARG100
|
3.5
|
14.8
|
1.0
|
|
HG21
|
A:VAL104
|
3.6
|
21.1
|
1.0
|
|
CG2
|
A:VAL104
|
3.6
|
17.6
|
1.0
|
|
C
|
A:GLY12
|
3.7
|
14.6
|
1.0
|
|
O
|
A:GLY12
|
3.8
|
15.9
|
1.0
|
|
HD2
|
A:TYR103
|
3.9
|
20.2
|
1.0
|
|
CA
|
A:GLY12
|
3.9
|
14.7
|
1.0
|
|
CZ
|
A:ARG100
|
3.9
|
15.9
|
1.0
|
|
HG2
|
A:ARG13
|
4.0
|
20.6
|
1.0
|
|
N
|
A:ARG13
|
4.1
|
15.0
|
1.0
|
|
HE2
|
A:TYR103
|
4.1
|
18.9
|
1.0
|
|
NE
|
A:ARG100
|
4.1
|
15.9
|
1.0
|
|
CG
|
A:ARG13
|
4.2
|
17.1
|
1.0
|
|
HA
|
A:ARG13
|
4.2
|
18.3
|
1.0
|
|
HD2
|
A:ARG100
|
4.2
|
18.2
|
1.0
|
|
O
|
A:HOH706
|
4.2
|
18.1
|
1.0
|
|
HA3
|
A:GLY12
|
4.4
|
17.7
|
1.0
|
|
HD12
|
A:ILE161
|
4.4
|
24.9
|
1.0
|
|
H
|
A:ARG13
|
4.5
|
18.0
|
1.0
|
|
O
|
A:HOH617
|
4.5
|
18.7
|
1.0
|
|
CD2
|
A:TYR103
|
4.5
|
16.8
|
1.0
|
|
HD13
|
A:ILE161
|
4.5
|
24.9
|
1.0
|
|
HD11
|
A:ILE161
|
4.6
|
24.9
|
1.0
|
|
CA
|
A:ARG13
|
4.6
|
15.2
|
1.0
|
|
CE2
|
A:TYR103
|
4.7
|
15.7
|
1.0
|
|
CD1
|
A:ILE161
|
4.7
|
20.8
|
1.0
|
|
OD1
|
A:ASN204
|
4.9
|
17.2
|
1.0
|
|
CB
|
A:ARG100
|
5.0
|
14.1
|
1.0
|
|
HE
|
A:ARG100
|
5.0
|
19.2
|
1.0
|
|
Sodium binding site 2 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 2 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na504
b:24.1
occ:1.00
|
O
|
A:HOH713
|
2.7
|
21.3
|
1.0
|
|
O
|
A:GLY95
|
2.8
|
14.5
|
1.0
|
|
O
|
A:HOH643
|
2.8
|
20.1
|
1.0
|
|
O
|
A:HOH661
|
2.8
|
19.4
|
1.0
|
|
HB2
|
A:ASP98
|
2.9
|
19.3
|
1.0
|
|
HA2
|
A:GLY95
|
3.2
|
18.3
|
1.0
|
|
HB2
|
A:LEU99
|
3.4
|
20.2
|
1.0
|
|
HB3
|
A:ASP98
|
3.4
|
19.3
|
1.0
|
|
H
|
A:LEU99
|
3.5
|
17.0
|
1.0
|
|
CB
|
A:ASP98
|
3.6
|
16.0
|
1.0
|
|
C
|
A:GLY95
|
3.6
|
14.8
|
1.0
|
|
HD1
|
B:TYR49
|
3.7
|
23.5
|
1.0
|
|
CA
|
A:GLY95
|
3.7
|
15.2
|
1.0
|
|
HA3
|
A:GLY95
|
3.8
|
18.3
|
1.0
|
|
N
|
A:LEU99
|
3.9
|
14.2
|
1.0
|
|
CD1
|
B:TYR49
|
3.9
|
19.5
|
1.0
|
|
O
|
A:HOH718
|
4.0
|
22.5
|
1.0
|
|
HZ
|
A:PHE129
|
4.0
|
21.5
|
1.0
|
|
HE1
|
B:TYR49
|
4.2
|
23.1
|
1.0
|
|
CE1
|
B:TYR49
|
4.2
|
19.2
|
1.0
|
|
CB
|
A:LEU99
|
4.3
|
16.8
|
1.0
|
|
HB3
|
B:TYR49
|
4.3
|
24.1
|
1.0
|
|
O
|
B:HOH504
|
4.3
|
23.2
|
1.0
|
|
HD1
|
A:HIS125
|
4.4
|
26.7
|
1.0
|
|
HE2
|
A:PHE129
|
4.4
|
22.0
|
1.0
|
|
OD2
|
A:ASP98
|
4.5
|
20.7
|
1.0
|
|
C
|
A:ASP98
|
4.5
|
15.1
|
1.0
|
|
HZ2
|
A:LYS102
|
4.5
|
40.0
|
1.0
|
|
CA
|
A:LEU99
|
4.5
|
14.3
|
1.0
|
|
CA
|
A:ASP98
|
4.5
|
14.5
|
1.0
|
|
HA
|
A:LEU99
|
4.6
|
17.2
|
1.0
|
|
CG
|
A:ASP98
|
4.6
|
18.7
|
1.0
|
|
H
|
A:ASP98
|
4.6
|
17.1
|
1.0
|
|
CG
|
B:TYR49
|
4.6
|
19.3
|
1.0
|
|
HB3
|
A:LEU99
|
4.6
|
20.2
|
1.0
|
|
HZ3
|
A:LYS102
|
4.6
|
40.0
|
1.0
|
|
HB3
|
A:HIS125
|
4.6
|
24.0
|
1.0
|
|
CZ
|
A:PHE129
|
4.7
|
17.9
|
1.0
|
|
HE22
|
B:GLN64
|
4.7
|
21.8
|
1.0
|
|
HE21
|
B:GLN64
|
4.8
|
21.8
|
1.0
|
|
N
|
A:VAL96
|
4.8
|
14.8
|
1.0
|
|
HD13
|
A:LEU99
|
4.9
|
21.4
|
1.0
|
|
N
|
A:ASP98
|
4.9
|
14.2
|
1.0
|
|
CE2
|
A:PHE129
|
4.9
|
18.3
|
1.0
|
|
CB
|
B:TYR49
|
5.0
|
20.1
|
1.0
|
|
HD21
|
A:LEU99
|
5.0
|
24.7
|
1.0
|
|
ND1
|
A:HIS125
|
5.0
|
22.2
|
1.0
|
|
NZ
|
A:LYS102
|
5.0
|
33.3
|
1.0
|
|
Sodium binding site 3 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 3 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 3 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na505
b:48.8
occ:1.00
|
O
|
A:HOH784
|
2.6
|
27.8
|
1.0
|
|
O
|
A:HOH903
|
2.8
|
47.5
|
1.0
|
|
HD3
|
A:ARG201
|
3.0
|
33.8
|
1.0
|
|
HB2
|
A:PRO9
|
3.2
|
26.9
|
1.0
|
|
HG3
|
A:ARG201
|
3.3
|
31.9
|
1.0
|
|
HA
|
A:PRO9
|
3.3
|
24.4
|
1.0
|
|
O
|
A:HOH629
|
3.4
|
32.1
|
1.0
|
|
HB3
|
A:PRO9
|
3.6
|
26.9
|
1.0
|
|
CB
|
A:PRO9
|
3.6
|
22.4
|
1.0
|
|
CA
|
A:PRO9
|
3.8
|
20.3
|
1.0
|
|
CD
|
A:ARG201
|
3.8
|
28.1
|
1.0
|
|
HH11
|
A:ARG201
|
3.9
|
35.0
|
1.0
|
|
CG
|
A:ARG201
|
4.0
|
26.6
|
1.0
|
|
O
|
A:PRO9
|
4.0
|
22.4
|
1.0
|
|
C
|
A:PRO9
|
4.1
|
20.0
|
1.0
|
|
HD2
|
A:ARG201
|
4.1
|
33.8
|
1.0
|
|
O
|
A:HOH620
|
4.2
|
38.3
|
1.0
|
|
HA
|
A:ARG201
|
4.2
|
27.4
|
1.0
|
|
HG21
|
A:VAL32
|
4.2
|
34.7
|
1.0
|
|
HB2
|
A:ARG201
|
4.2
|
30.1
|
1.0
|
|
HG22
|
A:VAL32
|
4.3
|
34.7
|
1.0
|
|
HG11
|
A:VAL32
|
4.3
|
35.8
|
1.0
|
|
CB
|
A:ARG201
|
4.5
|
25.0
|
1.0
|
|
HD2
|
A:PRO202
|
4.7
|
27.4
|
1.0
|
|
NH1
|
A:ARG201
|
4.7
|
29.2
|
1.0
|
|
CG2
|
A:VAL32
|
4.8
|
28.9
|
1.0
|
|
O
|
A:HOH665
|
4.8
|
20.1
|
1.0
|
|
HG2
|
A:ARG201
|
4.8
|
31.9
|
1.0
|
|
CA
|
A:ARG201
|
4.8
|
22.8
|
1.0
|
|
N
|
A:VAL10
|
4.9
|
19.2
|
1.0
|
|
NE
|
A:ARG201
|
5.0
|
28.3
|
1.0
|
|
Sodium binding site 4 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 4 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 4 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na506
b:56.3
occ:1.00
|
N1
|
A:GTB502
|
2.7
|
19.0
|
1.0
|
|
HN12
|
A:GTB502
|
2.8
|
22.8
|
1.0
|
|
OE2
|
A:GLU97
|
2.9
|
17.2
|
1.0
|
|
HN11
|
A:GTB502
|
3.1
|
22.8
|
1.0
|
|
O
|
A:HOH754
|
3.3
|
41.1
|
1.0
|
|
O11
|
A:GTB502
|
3.5
|
17.7
|
1.0
|
|
HH22
|
A:ARG13
|
3.5
|
21.8
|
1.0
|
|
HH12
|
A:ARG13
|
3.6
|
19.2
|
1.0
|
|
OD1
|
B:ASP98
|
3.6
|
23.0
|
1.0
|
|
CD
|
A:GLU97
|
3.6
|
15.9
|
1.0
|
|
NH2
|
A:ARG13
|
3.6
|
18.2
|
1.0
|
|
HB11
|
A:GTB502
|
3.7
|
21.2
|
1.0
|
|
NH1
|
A:ARG13
|
3.7
|
16.0
|
1.0
|
|
CZ
|
A:ARG13
|
3.7
|
16.5
|
1.0
|
|
CA1
|
A:GTB502
|
3.8
|
17.7
|
1.0
|
|
O
|
A:HOH777
|
3.9
|
41.4
|
1.0
|
|
HH21
|
A:ARG13
|
4.0
|
21.8
|
1.0
|
|
O
|
B:HOH463
|
4.1
|
39.0
|
1.0
|
|
OE1
|
A:GLU97
|
4.1
|
16.5
|
1.0
|
|
CB1
|
A:GTB502
|
4.1
|
17.6
|
1.0
|
|
C1
|
A:GTB502
|
4.1
|
16.9
|
1.0
|
|
HH11
|
A:ARG13
|
4.1
|
19.2
|
1.0
|
|
O
|
A:HOH859
|
4.2
|
34.8
|
1.0
|
|
HB12
|
A:GTB502
|
4.2
|
21.2
|
1.0
|
|
O
|
A:HOH651
|
4.2
|
23.9
|
1.0
|
|
HG2
|
A:GLU97
|
4.3
|
17.7
|
1.0
|
|
HD22
|
A:ASN66
|
4.3
|
21.7
|
1.0
|
|
O
|
B:HOH572
|
4.4
|
35.9
|
1.0
|
|
CG
|
A:GLU97
|
4.5
|
14.7
|
1.0
|
|
O
|
B:HOH511
|
4.5
|
17.7
|
1.0
|
|
NE
|
A:ARG13
|
4.5
|
16.9
|
1.0
|
|
CG
|
B:ASP98
|
4.5
|
19.9
|
1.0
|
|
HD21
|
A:ASN66
|
4.5
|
21.7
|
1.0
|
|
OD2
|
B:ASP98
|
4.6
|
20.9
|
1.0
|
|
OE1
|
A:GLN64
|
4.6
|
17.9
|
1.0
|
|
HG3
|
A:GLU97
|
4.6
|
17.7
|
1.0
|
|
HA1
|
A:GTB502
|
4.7
|
21.3
|
1.0
|
|
HE
|
A:ARG13
|
4.7
|
20.3
|
1.0
|
|
O
|
A:HOH743
|
4.8
|
28.4
|
1.0
|
|
ND2
|
A:ASN66
|
4.8
|
18.0
|
1.0
|
|
HG
|
A:SER65
|
4.9
|
19.6
|
1.0
|
|
HD3
|
A:ARG13
|
4.9
|
20.2
|
1.0
|
|
O
|
A:HOH746
|
4.9
|
22.9
|
1.0
|
|
Sodium binding site 5 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 5 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 5 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na507
b:58.0
occ:1.00
|
O
|
A:HOH777
|
2.1
|
41.4
|
1.0
|
|
C2
|
B:GOL301
|
2.2
|
31.8
|
1.0
|
|
H11
|
B:GOL301
|
2.5
|
41.2
|
1.0
|
|
C1
|
B:GOL301
|
2.6
|
34.4
|
1.0
|
|
O1
|
B:GOL301
|
2.8
|
35.8
|
1.0
|
|
HD22
|
A:ASN66
|
2.8
|
21.7
|
1.0
|
|
HB2
|
A:ASN66
|
2.9
|
18.9
|
1.0
|
|
O
|
A:HOH638
|
2.9
|
20.3
|
1.0
|
|
H31
|
B:GOL301
|
3.0
|
34.8
|
1.0
|
|
C3
|
B:GOL301
|
3.1
|
29.0
|
1.0
|
|
HH12
|
A:ARG70
|
3.2
|
21.0
|
1.0
|
|
OD1
|
B:ASP94
|
3.2
|
21.8
|
1.0
|
|
O2
|
B:GOL301
|
3.2
|
33.2
|
1.0
|
|
ND2
|
A:ASN66
|
3.3
|
18.0
|
1.0
|
|
HB3
|
A:ASN66
|
3.4
|
18.9
|
1.0
|
|
HO1
|
B:GOL301
|
3.4
|
42.9
|
1.0
|
|
CB
|
A:ASN66
|
3.5
|
15.7
|
1.0
|
|
CG
|
B:ASP94
|
3.5
|
20.0
|
1.0
|
|
H12
|
B:GOL301
|
3.5
|
41.2
|
1.0
|
|
HG2
|
A:GLU97
|
3.6
|
17.7
|
1.0
|
|
OD2
|
B:ASP94
|
3.6
|
21.1
|
1.0
|
|
CG
|
A:ASN66
|
3.7
|
16.4
|
1.0
|
|
O3
|
B:GOL301
|
3.8
|
22.7
|
1.0
|
|
HO2
|
B:GOL301
|
3.9
|
39.8
|
1.0
|
|
NH1
|
A:ARG70
|
3.9
|
17.5
|
1.0
|
|
HD21
|
A:ASN66
|
3.9
|
21.7
|
1.0
|
|
H32
|
B:GOL301
|
3.9
|
34.8
|
1.0
|
|
O
|
B:HOH463
|
3.9
|
39.0
|
1.0
|
|
HH11
|
A:ARG70
|
4.0
|
21.0
|
1.0
|
|
O
|
B:HOH511
|
4.0
|
17.7
|
1.0
|
|
O
|
A:HOH708
|
4.2
|
20.4
|
1.0
|
|
HO3
|
B:GOL301
|
4.3
|
27.3
|
1.0
|
|
HA
|
B:ASP94
|
4.3
|
19.9
|
1.0
|
|
HH12
|
B:ARG70
|
4.3
|
22.6
|
1.0
|
|
HB3
|
B:ASP94
|
4.3
|
20.6
|
1.0
|
|
CB
|
B:ASP94
|
4.5
|
17.1
|
1.0
|
|
CG
|
A:GLU97
|
4.5
|
14.7
|
1.0
|
|
OD1
|
A:ASP94
|
4.6
|
19.8
|
1.0
|
|
HB2
|
A:GLU97
|
4.6
|
17.7
|
1.0
|
|
HD22
|
A:ASN93
|
4.7
|
20.7
|
1.0
|
|
HH22
|
B:ARG70
|
4.7
|
23.6
|
1.0
|
|
OD1
|
A:ASN66
|
4.8
|
17.4
|
1.0
|
|
HH22
|
A:ARG70
|
4.9
|
21.5
|
1.0
|
|
CA
|
A:ASN66
|
4.9
|
15.8
|
1.0
|
|
HB3
|
A:GLU97
|
4.9
|
17.7
|
1.0
|
|
CA
|
B:ASP94
|
4.9
|
16.6
|
1.0
|
|
H
|
A:ASN66
|
4.9
|
18.6
|
1.0
|
|
HG2
|
B:GLU97
|
4.9
|
21.4
|
1.0
|
|
NH1
|
B:ARG70
|
5.0
|
18.9
|
1.0
|
|
CB
|
A:GLU97
|
5.0
|
14.7
|
1.0
|
|
Sodium binding site 6 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 6 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 6 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na508
b:22.6
occ:1.00
|
H
|
A:ALA16
|
2.1
|
17.8
|
1.0
|
|
O
|
A:HOH726
|
2.8
|
16.3
|
1.0
|
|
O
|
A:GLY12
|
2.8
|
15.9
|
1.0
|
|
H
|
A:GLU15
|
2.9
|
18.8
|
1.0
|
|
N
|
A:ALA16
|
3.0
|
14.8
|
1.0
|
|
HA
|
A:ARG13
|
3.1
|
18.3
|
1.0
|
|
HB2
|
A:ALA16
|
3.1
|
17.8
|
1.0
|
|
HB3
|
A:ALA16
|
3.2
|
17.8
|
1.0
|
|
OD2
|
A:ASP157
|
3.3
|
19.1
|
1.0
|
|
N
|
A:GLU15
|
3.3
|
15.6
|
1.0
|
|
C
|
A:ARG13
|
3.5
|
15.2
|
1.0
|
|
HH22
|
A:ARG100
|
3.5
|
20.1
|
1.0
|
|
CB
|
A:ALA16
|
3.5
|
14.8
|
1.0
|
|
O
|
A:HOH683
|
3.6
|
17.0
|
1.0
|
|
HH12
|
A:ARG100
|
3.6
|
19.4
|
1.0
|
|
N
|
A:CYS14
|
3.6
|
15.9
|
1.0
|
|
NH2
|
A:ARG100
|
3.7
|
16.7
|
1.0
|
|
CA
|
A:ARG13
|
3.7
|
15.2
|
1.0
|
|
CG
|
A:ASP157
|
3.7
|
18.2
|
1.0
|
|
HB3
|
A:GLU15
|
3.8
|
19.9
|
1.0
|
|
NH1
|
A:ARG100
|
3.8
|
16.2
|
1.0
|
|
O
|
A:ARG13
|
3.8
|
16.2
|
1.0
|
|
CZ
|
A:ARG100
|
3.8
|
15.9
|
1.0
|
|
CA
|
A:ALA16
|
3.8
|
15.0
|
1.0
|
|
H
|
A:CYS14
|
3.8
|
19.1
|
1.0
|
|
C
|
A:GLY12
|
3.9
|
14.6
|
1.0
|
|
C
|
A:GLU15
|
3.9
|
16.3
|
1.0
|
|
CA
|
A:GLU15
|
3.9
|
16.5
|
1.0
|
|
C
|
A:CYS14
|
3.9
|
16.3
|
1.0
|
|
HH21
|
A:ARG100
|
4.1
|
20.1
|
1.0
|
|
HB2
|
A:GLU15
|
4.1
|
19.9
|
1.0
|
|
HB3
|
A:ASP157
|
4.1
|
19.8
|
1.0
|
|
CB
|
A:GLU15
|
4.2
|
16.6
|
1.0
|
|
O
|
A:HOH706
|
4.2
|
18.1
|
1.0
|
|
N
|
A:ARG13
|
4.2
|
15.0
|
1.0
|
|
CA
|
A:CYS14
|
4.2
|
16.8
|
1.0
|
|
HH11
|
A:ARG100
|
4.3
|
19.4
|
1.0
|
|
OD1
|
A:ASP157
|
4.3
|
19.6
|
1.0
|
|
H
|
A:MET17
|
4.3
|
19.2
|
1.0
|
|
CB
|
A:ASP157
|
4.4
|
16.5
|
1.0
|
|
HA
|
A:ALA16
|
4.4
|
18.0
|
1.0
|
|
HA
|
A:CYS14
|
4.4
|
20.1
|
1.0
|
|
HB1
|
A:ALA16
|
4.4
|
17.8
|
1.0
|
|
HB2
|
A:ASP157
|
4.5
|
19.8
|
1.0
|
|
OD1
|
A:ASN154
|
4.6
|
15.2
|
1.0
|
|
NE
|
A:ARG100
|
4.6
|
15.9
|
1.0
|
|
O
|
A:ARG11
|
4.7
|
16.0
|
1.0
|
|
O
|
A:CYS14
|
4.8
|
17.6
|
1.0
|
|
HA
|
A:GLU15
|
4.9
|
19.8
|
1.0
|
|
HE
|
A:ARG100
|
4.9
|
19.2
|
1.0
|
|
N
|
A:MET17
|
4.9
|
16.0
|
1.0
|
|
C
|
A:ALA16
|
5.0
|
15.5
|
1.0
|
|
HD3
|
A:ARG100
|
5.0
|
18.2
|
1.0
|
|
Sodium binding site 7 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 7 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 7 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na303
b:21.8
occ:1.00
|
HD22
|
B:ASN110
|
2.5
|
31.9
|
1.0
|
|
HA
|
B:LEU106
|
3.1
|
24.5
|
1.0
|
|
O
|
B:HOH469
|
3.1
|
21.4
|
1.0
|
|
O
|
B:HOH487
|
3.1
|
23.1
|
1.0
|
|
HB3
|
B:ASN110
|
3.2
|
29.7
|
1.0
|
|
HB2
|
B:LEU106
|
3.3
|
24.5
|
1.0
|
|
O
|
B:HOH635
|
3.3
|
38.4
|
1.0
|
|
HD13
|
B:LEU106
|
3.4
|
25.5
|
1.0
|
|
ND2
|
B:ASN110
|
3.4
|
26.5
|
1.0
|
|
HD12
|
B:LEU106
|
3.4
|
25.5
|
1.0
|
|
HA3
|
B:GLY114
|
3.6
|
29.1
|
1.0
|
|
HG22
|
B:THR105
|
3.8
|
25.6
|
1.0
|
|
CA
|
B:LEU106
|
3.8
|
20.4
|
1.0
|
|
CD1
|
B:LEU106
|
3.8
|
21.2
|
1.0
|
|
HD21
|
B:ASN110
|
3.9
|
31.9
|
1.0
|
|
CB
|
B:LEU106
|
3.9
|
20.4
|
1.0
|
|
CB
|
B:ASN110
|
4.0
|
24.8
|
1.0
|
|
N
|
B:LEU106
|
4.2
|
20.6
|
1.0
|
|
CG
|
B:ASN110
|
4.2
|
27.4
|
1.0
|
|
HD2
|
B:TYR118
|
4.2
|
22.3
|
1.0
|
|
HB2
|
B:ASN110
|
4.3
|
29.7
|
1.0
|
|
H
|
B:LEU106
|
4.3
|
24.7
|
1.0
|
|
HB2
|
B:TYR118
|
4.5
|
21.5
|
1.0
|
|
CA
|
B:GLY114
|
4.5
|
24.2
|
1.0
|
|
CG
|
B:LEU106
|
4.5
|
21.5
|
1.0
|
|
HD11
|
B:LEU106
|
4.6
|
25.5
|
1.0
|
|
O
|
B:ASN110
|
4.7
|
24.2
|
1.0
|
|
CG2
|
B:THR105
|
4.7
|
21.4
|
1.0
|
|
HA2
|
B:GLY114
|
4.7
|
29.1
|
1.0
|
|
C
|
B:THR105
|
4.7
|
20.3
|
1.0
|
|
O
|
B:HOH689
|
4.8
|
23.9
|
1.0
|
|
HB3
|
B:LEU106
|
4.8
|
24.5
|
1.0
|
|
O
|
B:GLY114
|
4.8
|
22.2
|
1.0
|
|
O
|
B:HOH573
|
4.8
|
29.8
|
1.0
|
|
HB
|
B:THR105
|
4.9
|
24.7
|
1.0
|
|
HG21
|
B:THR105
|
4.9
|
25.6
|
1.0
|
|
O
|
B:HOH695
|
4.9
|
34.1
|
1.0
|
|
O
|
B:THR105
|
4.9
|
20.1
|
1.0
|
|
O
|
B:HOH664
|
4.9
|
24.7
|
1.0
|
|
C
|
B:GLY114
|
4.9
|
22.6
|
1.0
|
|
Sodium binding site 8 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 8 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 8 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na304
b:45.5
occ:1.00
|
HA
|
B:ALA121
|
2.7
|
25.5
|
1.0
|
|
HG2
|
B:LYS120
|
2.8
|
40.9
|
1.0
|
|
O
|
B:HOH475
|
2.9
|
22.6
|
1.0
|
|
O
|
B:HOH687
|
3.0
|
39.6
|
1.0
|
|
HB2
|
B:ALA121
|
3.1
|
25.4
|
1.0
|
|
HB3
|
B:LYS120
|
3.3
|
34.1
|
1.0
|
|
CA
|
B:ALA121
|
3.3
|
21.2
|
1.0
|
|
N
|
B:ALA121
|
3.4
|
21.8
|
1.0
|
|
C
|
B:LYS120
|
3.4
|
24.2
|
1.0
|
|
O
|
B:LYS120
|
3.5
|
25.8
|
1.0
|
|
CG
|
B:LYS120
|
3.5
|
34.1
|
1.0
|
|
CB
|
B:ALA121
|
3.7
|
21.2
|
1.0
|
|
HG3
|
B:LYS120
|
3.7
|
40.9
|
1.0
|
|
H
|
B:ALA121
|
3.8
|
26.1
|
1.0
|
|
CB
|
B:LYS120
|
3.8
|
28.4
|
1.0
|
|
HB1
|
B:ALA121
|
4.1
|
25.4
|
1.0
|
|
O
|
B:HOH522
|
4.3
|
31.1
|
1.0
|
|
CA
|
B:LYS120
|
4.3
|
25.7
|
1.0
|
|
O
|
B:HOH636
|
4.3
|
46.3
|
1.0
|
|
HB3
|
B:ALA121
|
4.4
|
25.4
|
1.0
|
|
O
|
B:ASP117
|
4.6
|
19.8
|
1.0
|
|
O
|
B:HOH589
|
4.6
|
38.5
|
1.0
|
|
HB2
|
B:LYS120
|
4.7
|
34.1
|
1.0
|
|
C
|
B:ALA121
|
4.7
|
21.1
|
1.0
|
|
CD
|
B:LYS120
|
4.8
|
37.8
|
1.0
|
|
HA
|
B:LYS120
|
4.8
|
30.8
|
1.0
|
|
O
|
B:HOH693
|
4.8
|
47.2
|
1.0
|
|
HD3
|
B:LYS120
|
4.8
|
45.4
|
1.0
|
|
O
|
B:HOH640
|
4.9
|
24.4
|
1.0
|
|
Sodium binding site 9 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 9 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 9 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na305
b:52.6
occ:1.00
|
H
|
B:ILE148
|
2.5
|
39.0
|
1.0
|
|
HG22
|
B:ILE148
|
3.0
|
39.5
|
1.0
|
|
HA
|
B:GLN147
|
3.2
|
42.9
|
1.0
|
|
OE1
|
B:GLN147
|
3.3
|
48.9
|
1.0
|
|
N
|
B:ILE148
|
3.4
|
32.5
|
1.0
|
|
HB
|
B:ILE148
|
3.6
|
39.4
|
1.0
|
|
HG21
|
B:ILE148
|
3.6
|
39.5
|
1.0
|
|
HB3
|
B:GLN147
|
3.6
|
45.8
|
1.0
|
|
HH12
|
B:ARG186
|
3.7
|
41.6
|
1.0
|
|
CG2
|
B:ILE148
|
3.7
|
32.9
|
1.0
|
|
O
|
B:HOH516
|
3.8
|
39.3
|
1.0
|
|
O
|
B:HOH586
|
3.8
|
50.1
|
1.0
|
|
HH22
|
B:ARG186
|
3.9
|
42.5
|
1.0
|
|
HE2
|
B:PHE142
|
3.9
|
41.7
|
1.0
|
|
HZ
|
B:PHE142
|
3.9
|
42.2
|
1.0
|
|
CA
|
B:GLN147
|
4.0
|
35.7
|
1.0
|
|
CB
|
B:ILE148
|
4.0
|
32.8
|
1.0
|
|
CD
|
B:GLN147
|
4.2
|
47.7
|
1.0
|
|
C
|
B:GLN147
|
4.2
|
33.6
|
1.0
|
|
CE2
|
B:PHE142
|
4.2
|
34.7
|
1.0
|
|
CZ
|
B:PHE142
|
4.2
|
35.2
|
1.0
|
|
CB
|
B:GLN147
|
4.2
|
38.2
|
1.0
|
|
CA
|
B:ILE148
|
4.3
|
31.3
|
1.0
|
|
NH1
|
B:ARG186
|
4.4
|
34.7
|
1.0
|
|
HG23
|
B:ILE148
|
4.5
|
39.5
|
1.0
|
|
NH2
|
B:ARG186
|
4.6
|
35.4
|
1.0
|
|
O
|
B:HOH678
|
4.6
|
53.7
|
1.0
|
|
CG
|
B:GLN147
|
4.8
|
42.8
|
1.0
|
|
O
|
B:ASP146
|
4.9
|
33.8
|
1.0
|
|
HE22
|
B:GLN147
|
4.9
|
59.8
|
1.0
|
|
NE2
|
B:GLN147
|
4.9
|
49.8
|
1.0
|
|
O
|
B:ILE148
|
5.0
|
32.0
|
1.0
|
|
CZ
|
B:ARG186
|
5.0
|
34.4
|
1.0
|
|
HH11
|
B:ARG186
|
5.0
|
41.6
|
1.0
|
|
Sodium binding site 10 out
of 11 in 8c5d
Go back to
Sodium Binding Sites List in 8c5d
Sodium binding site 10 out
of 11 in the Glutathione Transferase P1-1 From Mus Musculus
 Mono view
 Stereo pair view
|
|
A full contact list of Sodium with other atoms in the Na binding
site number 10 of Glutathione Transferase P1-1 From Mus Musculus within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Na306
b:58.3
occ:1.00
|
O
|
B:HOH560
|
2.8
|
27.1
|
1.0
|
|
HG11
|
B:VAL104
|
3.3
|
25.2
|
1.0
|
|
H'2
|
B:GTB302
|
3.4
|
31.6
|
1.0
|
|
OE1
|
B:GTB302
|
3.5
|
23.5
|
1.0
|
|
HA2
|
B:GTB302
|
3.5
|
28.4
|
1.0
|
|
O
|
B:HOH533
|
3.7
|
20.1
|
1.0
|
|
O
|
B:HOH538
|
3.8
|
32.5
|
1.0
|
|
HG12
|
B:VAL104
|
3.8
|
25.2
|
1.0
|
|
CG1
|
B:VAL104
|
4.0
|
21.0
|
1.0
|
|
O
|
B:HOH576
|
4.0
|
40.8
|
1.0
|
|
HE22
|
B:GLN51
|
4.1
|
29.4
|
1.0
|
|
HG13
|
B:VAL104
|
4.2
|
25.2
|
1.0
|
|
O
|
B:HOH525
|
4.3
|
22.6
|
1.0
|
|
C'
|
B:GTB302
|
4.3
|
26.4
|
1.0
|
|
CA2
|
B:GTB302
|
4.5
|
23.6
|
1.0
|
|
HN3
|
B:GTB302
|
4.5
|
30.1
|
1.0
|
|
H2'
|
B:GTB302
|
4.5
|
37.2
|
1.0
|
|
H'1
|
B:GTB302
|
4.6
|
31.6
|
1.0
|
|
CD1
|
B:GTB302
|
4.6
|
23.6
|
1.0
|
|
NE2
|
B:GLN51
|
4.8
|
24.5
|
1.0
|
|
O
|
B:HOH526
|
4.9
|
22.3
|
1.0
|
|
SG2
|
B:GTB302
|
4.9
|
24.9
|
1.0
|
|
HE21
|
B:GLN51
|
4.9
|
29.4
|
1.0
|
|
Reference:
O.Kupreienko,
F.Pouliou,
K.Konstandinidis,
I.Axarli,
E.Douni,
A.C.Papageorgiou,
N.E.Labrou.
Inhibition Analysis and High-Resolution Crystal Structure of Mus Musculus Glutathione Transferase P1-1. Biomolecules V. 13 2023.
ISSN: ESSN 2218-273X
PubMed: 37189361
DOI: 10.3390/BIOM13040613
Page generated: Fri Jul 28 03:09:53 2023
|
