Sodium in PDB 7y7w: Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom

The structure of Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Sodium atom in the Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom (pdb code 7y7w). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom, PDB code: 7y7w:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Na705 b:37.8 occ:1.00 OD1 A:ASN66 2.2 33.9 1.0 O A:ALA61 2.2 36.1 1.0 OE1 A:ABU701 2.3 34.7 1.0 OG A:SER295 2.4 33.2 1.0 OD1 A:ASN327 2.7 36.8 1.0 O A:SER295 2.8 33.2 1.0 CG A:ASN66 3.1 33.9 1.0 ND2 A:ASN66 3.4 33.9 1.0 CD A:ABU701 3.4 34.7 1.0 ND2 A:ASN327 3.4 36.8 1.0 CB A:SER295 3.4 33.2 1.0 CG A:ASN327 3.5 36.8 1.0 C A:ALA61 3.5 36.1 1.0 C A:SER295 3.5 33.2 1.0 CA A:SER295 3.6 33.2 1.0 CA A:ILE62 4.0 36.3 1.0 CG A:ABU701 4.0 34.7 1.0 N A:GLY63 4.1 33.8 1.0 N A:ILE62 4.2 36.3 1.0 N A:ASN66 4.2 33.9 1.0 OE2 A:ABU701 4.3 34.7 1.0 CB A:ASN66 4.4 33.9 1.0 C A:GLY65 4.5 32.8 1.0 C A:ILE62 4.5 36.3 1.0 CA A:ALA61 4.5 36.1 1.0 CA A:GLY65 4.6 32.8 1.0 CA A:ASN66 4.7 33.9 1.0 N A:TYR296 4.8 34.8 1.0 CB A:ASN327 4.9 36.8 1.0 N A:GLY65 4.9 32.8 1.0

Sodium binding site 2 out of 2 in the Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Cryo-Em Structure of Human Gaba Transporter GAT1 Bound with Gaba in Nacl Solution in An Inward-Occluded State at 2.4 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Na706 b:36.5 occ:1.00 O A:HOH836 2.3 37.1 1.0 O A:GLY59 2.3 38.7 1.0 OD2 A:ASP395 2.4 39.5 1.0 O A:ILE62 2.5 36.3 1.0 O A:LEU392 2.8 37.8 1.0 OG A:SER396 3.2 35.4 1.0 CG A:ASP395 3.3 39.5 1.0 C A:GLY59 3.5 38.7 1.0 C A:ILE62 3.6 36.3 1.0 N A:SER396 3.7 35.4 1.0 C A:LEU392 3.8 37.8 1.0 OD1 A:ASP395 3.8 39.5 1.0 CB A:SER396 3.9 35.4 1.0 CA A:GLY63 4.0 33.8 1.0 CB A:ASP395 4.2 39.5 1.0 CA A:LEU392 4.2 37.8 1.0 CA A:SER396 4.3 35.4 1.0 CA A:GLY59 4.3 38.7 1.0 N A:GLY63 4.3 33.8 1.0 C A:ASP395 4.4 39.5 1.0 N A:TYR60 4.5 36.8 1.0 CA A:TYR60 4.7 36.8 1.0 CA A:ASP395 4.7 39.5 1.0 O A:TYR60 4.7 36.8 1.0 CD1 A:LEU392 4.7 37.8 1.0 C A:TYR60 4.7 36.8 1.0 O A:MET391 4.7 42.8 1.0 CA A:ILE62 4.8 36.3 1.0 N A:ILE62 4.8 36.3 1.0 CG A:LEU392 4.8 37.8 1.0 N A:ASP395 4.8 39.5 1.0 O A:VAL58 4.9 39.8 1.0 N A:GLY393 5.0 35.6 1.0

A.Zhu, J.Huang, F.Kong, J.Tan, J.Lei, Y.Yuan, C.Yan. Structural Investigation of the Gaba Transporter GAT1 To Be Published.