Sodium in PDB 7sjq: Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T-Cell Engager

The structure of Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T-Cell Engager, PDB code: 7sjq was solved by P.B.Rupert, R.Strong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.04 / 2.00
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	56.04, 65.33, 99.912, 90, 90, 90
R / Rfree (%)	19.1 / 23.2

The binding sites of Sodium atom in the Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T-Cell Engager (pdb code 7sjq). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T-Cell Engager, PDB code: 7sjq:

Sodium binding site 1 out of 1 in the Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T-Cell Engager


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T-Cell Engager within 5.0Å range: probe atom residue distance (Å) B Occ A:Na204 b:44.1 occ:1.00 OE1 A:GLU31 2.6 30.3 1.0 CB A:GLU31 3.5 24.6 1.0 CD A:GLU31 3.6 29.0 1.0 CG A:PRO133 3.9 20.6 1.0 CG A:GLU31 4.1 26.7 1.0 O A:HOH345 4.4 25.9 1.0 OE2 A:GLU31 4.6 30.8 1.0 CB A:PRO133 4.6 20.9 1.0 CA A:GLU31 4.7 22.6 1.0 CD A:PRO133 4.8 20.4 1.0 ND2 A:ASN131 4.9 20.5 0.5

Z.R.Crook, E.J.Girard, G.P.Sevilla, M.Y.Brusniak, P.B.Rupert, D.J.Friend, M.M.Gewe, M.Clarke, I.Lin, R.Ruff, F.Pakiam, T.D.Phi, A.Bandaranayake, C.E.Correnti, A.J.Mhyre, N.W.Nairn, R.K.Strong, J.M.Olson. Ex Silico Engineering of Cystine-Dense Peptides Yielding A Potent Bispecific T Cell Engager. Sci Transl Med V. 14 N0402 2022.
ISSN: ESSN 1946-6242
PubMed: 35584229
DOI: 10.1126/SCITRANSLMED.ABN0402