Sodium in PDB 7p0c: Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure

All present enzymatic activity of Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure:
1.7.3.3;

The structure of Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure, PDB code: 7p0c was solved by N.Colloc'h, T.Prange, E.Girard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.15
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	79.53, 95.63, 104.754, 90, 90, 90
R / Rfree (%)	18.9 / 24.8

The binding sites of Sodium atom in the Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure (pdb code 7p0c). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure, PDB code: 7p0c:

Sodium binding site 1 out of 1 in the Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Urate Oxidase with 8-Azaxanthine Under 210 Mpa Pressure within 5.0Å range: probe atom residue distance (Å) B Occ A:Na403 b:30.2 occ:1.00 O A:ILE88 2.3 25.8 1.0 O A:ILE94 2.3 25.6 1.0 OE1 A:GLU136 2.3 32.1 1.0 O A:TYR91 2.4 31.0 1.0 O A:HOH506 2.5 37.1 1.0 C A:ILE88 3.2 27.8 1.0 CD A:GLU136 3.4 34.6 1.0 O A:ASN92 3.4 40.2 1.0 C A:ILE94 3.5 24.1 1.0 C A:TYR91 3.5 35.3 1.0 CA A:ILE88 3.7 27.7 1.0 C A:ASN92 3.7 39.3 1.0 CA A:ASN92 3.8 41.8 1.0 OE2 A:GLU136 3.9 39.7 1.0 ND1 A:HIS95 4.1 33.5 1.0 CB A:ILE88 4.1 29.1 1.0 N A:ASN92 4.1 38.2 1.0 N A:ILE94 4.1 29.3 1.0 CA A:ILE94 4.4 25.2 1.0 N A:HIS95 4.4 22.3 1.0 CA A:HIS95 4.4 23.3 1.0 N A:GLU89 4.5 26.9 1.0 CG A:GLU136 4.6 32.4 1.0 N A:HIS93 4.6 33.4 1.0 CE1 A:HIS95 4.6 32.9 1.0 O A:PHE87 4.7 26.0 1.0 CA A:TYR91 4.7 32.4 1.0 CB A:ILE94 4.8 26.0 1.0 N A:TYR91 4.8 30.9 1.0 CG2 A:ILE88 4.9 28.9 1.0 C A:HIS93 5.0 30.4 1.0 CB A:GLU136 5.0 29.9 1.0 CA A:GLU89 5.0 26.4 1.0 N A:ILE88 5.0 25.3 1.0

T.Prange, P.Carpentier, A.C.Dhaussy, E.Girard, N.Colloc'h. Comparative Study of the Effects of High Hydrostatic Pressure Per Se and High Argon Pressure on Urate Oxidase Ligand Stabilization Acta Cryst. D V. 78 162 2022.
DOI: 10.1107/S2059798321012134