Sodium in PDB 7mik: Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius

The binding sites of Sodium atom in the Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius (pdb code 7mik). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 4 binding sites of Sodium where determined in the Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius, PDB code: 7mik:
Jump to Sodium binding site number: 1; 2; 3; 4;

Sodium binding site 1 out of 4 in the Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius within 5.0Å range: probe atom residue distance (Å) B Occ A:Na911 b:0.0 occ:1.00 NA A:NA912 2.2 0.0 1.0 O A:GLY638 2.7 38.8 1.0 O C:GLY638 2.7 33.4 1.0 O D:GLY638 2.7 34.6 1.0 O B:GLY638 2.7 22.7 1.0 NA A:NA913 3.0 0.0 1.0 C A:GLY638 3.9 38.8 1.0 C D:GLY638 3.9 34.6 1.0 C C:GLY638 3.9 33.4 1.0 C B:GLY638 3.9 22.7 1.0 CA C:LEU639 4.6 37.8 1.0 CA A:LEU639 4.6 43.3 1.0 CA B:LEU639 4.6 26.6 1.0 CA D:LEU639 4.6 38.9 1.0 N C:LEU639 4.7 37.8 1.0 N A:LEU639 4.7 43.3 1.0 N D:LEU639 4.7 38.9 1.0 N B:LEU639 4.7 26.6 1.0 CA A:GLY638 4.8 38.8 1.0 CA D:GLY638 4.9 34.6 1.0 CA C:GLY638 4.9 33.4 1.0 CA B:GLY638 4.9 22.7 1.0

Sodium binding site 2 out of 4 in the Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius within 5.0Å range: probe atom residue distance (Å) B Occ A:Na912 b:0.0 occ:1.00 NA A:NA911 2.2 0.0 1.0 O C:GLY640 3.8 55.8 1.0 O A:GLY640 3.9 61.1 1.0 O D:GLY640 3.9 56.6 1.0 O B:GLY640 3.9 43.9 1.0 O A:GLY638 4.0 38.8 1.0 O D:GLY638 4.0 34.6 1.0 O B:GLY638 4.0 22.7 1.0 O C:GLY638 4.0 33.4 1.0 N C:GLY640 4.4 55.8 1.0 N A:GLY640 4.4 61.1 1.0 N B:GLY640 4.4 43.9 1.0 N D:GLY640 4.4 56.6 1.0 CA A:LEU639 4.8 43.3 1.0 CA C:LEU639 4.8 37.8 1.0 CA D:LEU639 4.8 38.9 1.0 CA B:LEU639 4.8 26.6 1.0 C C:LEU639 4.9 37.8 1.0 C C:GLY640 4.9 55.8 1.0 C A:LEU639 4.9 43.3 1.0 C D:LEU639 4.9 38.9 1.0 C B:LEU639 4.9 26.6 1.0 C A:GLY640 4.9 61.1 1.0 C D:GLY640 4.9 56.6 1.0 C B:GLY640 4.9 43.9 1.0

Sodium binding site 3 out of 4 in the Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius within 5.0Å range: probe atom residue distance (Å) B Occ A:Na913 b:0.0 occ:1.00 NA A:NA911 3.0 0.0 1.0 O C:GLY638 3.3 33.4 1.0 O B:GLY638 3.3 22.7 1.0 O A:GLY638 3.3 38.8 1.0 O D:GLY638 3.3 34.6 1.0 CA C:GLY638 3.9 33.4 1.0 CA A:GLY638 4.0 38.8 1.0 CA B:GLY638 4.0 22.7 1.0 CA D:GLY638 4.0 34.6 1.0 C C:GLY638 4.0 33.4 1.0 C A:GLY638 4.0 38.8 1.0 C B:GLY638 4.0 22.7 1.0 C D:GLY638 4.0 34.6 1.0 O C:ILE637 4.9 32.2 1.0 O A:ILE637 4.9 37.7 1.0 O B:ILE637 4.9 23.0 1.0 O D:ILE637 4.9 33.4 1.0

Sodium binding site 4 out of 4 in the Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Mouse TRPV3 in MSP2N2 Nanodiscs, Closed State at 42 Degrees Celsius within 5.0Å range: probe atom residue distance (Å) B Occ A:Na914 b:0.0 occ:1.00 CG2 C:ILE674 4.6 27.9 1.0 CG2 B:ILE674 4.6 17.4 1.0 CG2 A:ILE674 4.6 33.2 1.0 CG2 D:ILE674 4.6 29.3 1.0 O C:ILE674 4.7 27.9 1.0 O B:ILE674 4.7 17.4 1.0 O A:ILE674 4.7 33.2 1.0 O D:ILE674 4.7 29.3 1.0

K.D.Nadezhdin, A.Neuberger, Y.A.Trofimov, N.A.Krylov, V.Sinica, N.Kupko, V.Vlachova, E.Zakharian, R.G.Efremov, A.I.Sobolevsky. Structural Mechanism of Heat-Induced Opening of A Temperature-Sensitive Trp Channel. Nat.Struct.Mol.Biol. 2021.
ISSN: ESSN 1545-9985
PubMed: 34239124
DOI: 10.1038/S41594-021-00615-4