Sodium in PDB 7m3q: Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv)

All present enzymatic activity of Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv):
2.3.2.26;

The structure of Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv), PDB code: 7m3q was solved by A.Chowdhury, A.U.Singer, A.A.Ogunjimi, J.Teyra, W.Zhang, F.Sicheri, S.S.Sidhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	67.83 / 2.50
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	201.53, 72.068, 48.813, 90, 94.61, 90
R / Rfree (%)	20.3 / 23.5

The structure of Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv) also contains other interesting chemical elements:

Chlorine

(Cl)

6 atoms

The binding sites of Sodium atom in the Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv) (pdb code 7m3q). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv), PDB code: 7m3q:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na803 b:63.8 occ:1.00 OE2 A:GLU396 2.7 51.9 1.0 NZ A:LYS425 2.8 55.3 1.0 N A:GLY428 2.9 56.4 1.0 CA A:ARG427 3.4 59.5 1.0 C A:ARG427 3.6 52.9 1.0 CE A:LYS425 3.7 51.1 1.0 CD A:LYS425 3.8 50.1 1.0 O A:PHE426 3.8 55.9 1.0 CD A:GLU396 3.8 50.7 1.0 CA A:GLY428 3.9 53.5 1.0 N A:ARG427 4.2 54.3 1.0 CG A:GLU396 4.3 50.7 1.0 CB A:ARG427 4.3 60.5 1.0 CG A:LYS425 4.3 45.9 1.0 C A:PHE426 4.4 54.1 1.0 CG A:ARG427 4.4 63.5 1.0 N A:GLU429 4.5 54.1 1.0 C A:GLY428 4.7 58.6 1.0 O A:ARG427 4.8 55.4 1.0 OE1 A:GLU396 4.9 49.4 1.0 O A:GLU429 5.0 58.4 1.0

Sodium binding site 2 out of 2 in the Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv) within 5.0Å range: probe atom residue distance (Å) B Occ A:Na804 b:60.2 occ:1.00 O A:HOH952 2.3 63.0 1.0 O A:PHE495 3.8 53.4 1.0 O A:LEU383 4.0 59.7 1.0 CE1 A:PHE495 4.0 49.5 1.0 CA A:SER384 4.1 62.7 1.0 OE1 A:GLN387 4.2 54.5 1.0 C A:LEU383 4.2 59.0 1.0 CD A:GLN387 4.3 52.6 1.0 N A:SER384 4.3 63.4 1.0 NE2 A:GLN387 4.4 47.4 1.0 CB A:LEU383 4.4 57.2 1.0 CD1 A:PHE495 4.5 43.9 1.0 CZ A:PHE495 4.6 51.8 1.0 CB A:GLN387 4.6 51.9 1.0 CB A:SER384 4.7 59.7 1.0 C A:PHE495 5.0 52.3 1.0 OG A:SER384 5.0 72.2 1.0 CA A:LEU383 5.0 56.3 1.0

A.Chowdhury, A.U.Singer, A.A.Ogunjimi, J.Teyra, J.Chung, J.L.Wrana, W.Zhang, F.Sicheri, S.S.Sachdev. Structure of the SMURF2 Hect Domain with A High Affinity Ubiquitin Variant (Ubv) To Be Published.