Sodium in PDB 7lk8: Crystal Structure of Kpc-2 T215P Mutant

All present enzymatic activity of Crystal Structure of Kpc-2 T215P Mutant:
3.5.2.6;

The structure of Crystal Structure of Kpc-2 T215P Mutant, PDB code: 7lk8 was solved by I.Furey, T.Palzkill, L.Hu, B.V.V.Prasad, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.10 / 1.43
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.84, 71.66, 92.2, 90, 90, 90
R / Rfree (%)	15.7 / 18.6

The binding sites of Sodium atom in the Crystal Structure of Kpc-2 T215P Mutant (pdb code 7lk8). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of Kpc-2 T215P Mutant, PDB code: 7lk8:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Crystal Structure of Kpc-2 T215P Mutant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Kpc-2 T215P Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:27.1 occ:0.65 O A:HOH453 2.4 28.3 1.0 O A:HOH598 2.5 39.6 1.0 O A:ASP228 2.5 23.9 1.0 OG1 A:THR254 2.7 29.1 1.0 CB A:THR254 3.7 27.5 1.0 C A:ASP228 3.7 22.9 1.0 CG2 A:THR254 3.8 28.0 1.0 O A:HOH645 3.8 35.1 1.0 CA A:THR254 4.1 23.2 1.0 N A:ALA230 4.4 15.6 1.0 CA A:TRP229 4.5 17.8 1.0 N A:THR254 4.5 21.0 1.0 O A:HOH650 4.5 37.9 1.0 N A:TRP229 4.6 19.1 1.0 O A:TRP251 4.7 15.5 1.0 C A:TRP229 4.7 17.2 1.0 CA A:ASP228 4.7 26.4 1.0 O A:HOH578 4.7 43.3 1.0 CB A:ASP228 4.8 30.6 1.0

Sodium binding site 2 out of 3 in the Crystal Structure of Kpc-2 T215P Mutant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Kpc-2 T215P Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:36.9 occ:1.00 O A:HOH460 2.2 39.0 1.0 O A:HOH546 3.0 20.2 1.0 O A:THR56 3.3 16.1 1.0 O A:HOH462 3.6 27.0 1.0 O A:GLY289 4.0 15.1 1.0 CG2 A:VAL57 4.2 15.5 1.0 CA A:VAL57 4.2 13.4 1.0 C A:THR56 4.4 14.1 1.0 CB A:VAL57 4.6 14.0 1.0 N A:VAL57 4.8 13.6 1.0 CG1 A:VAL57 4.8 15.8 1.0 O A:HOH559 4.9 32.3 1.0 O A:HOH479 4.9 22.2 1.0 O A:HOH636 5.0 27.8 1.0 C A:GLY289 5.0 13.8 1.0

Sodium binding site 3 out of 3 in the Crystal Structure of Kpc-2 T215P Mutant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of Kpc-2 T215P Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Na301 b:37.4 occ:0.78 O B:HOH570 2.3 45.3 1.0 OG B:SER59 2.3 22.7 1.0 O B:SER59 2.4 20.4 1.0 O B:HOH540 2.9 25.9 1.0 C B:SER59 3.3 16.5 1.0 CB B:SER59 3.4 20.0 1.0 CA B:SER59 3.7 16.6 1.0 N B:SER59 3.8 15.0 1.0 O B:HOH503 4.0 29.4 1.0 O B:HOH567 4.3 23.9 1.0 N B:TYR60 4.4 15.3 1.0 O B:HOH571 4.7 29.4 1.0 CA B:TYR60 4.9 14.9 1.0

I.M.Furey, T.Palzkill. Crystal Structure of Kpc-2 T215P Mutant To Be Published.