Sodium in PDB 7l2u: Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State

The binding sites of Sodium atom in the Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State (pdb code 7l2u). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State, PDB code: 7l2u:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na803 b:1.9 occ:1.00 O C:GLY643 3.1 21.9 1.0 O A:GLY643 3.2 20.8 1.0 O D:GLY643 3.2 20.6 1.0 O B:GLY643 3.5 24.5 1.0 C C:GLY643 4.1 21.9 1.0 NA C:NA802 4.2 29.9 1.0 C A:GLY643 4.2 20.8 1.0 C D:GLY643 4.4 20.6 1.0 CA C:GLY643 4.6 21.9 1.0 C B:GLY643 4.6 24.5 1.0 CA A:GLY643 4.7 20.8 1.0 CA D:GLY643 5.0 20.6 1.0

Sodium binding site 2 out of 2 in the Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Cryo-Em Structure of Dktx-Bound Minimal TRPV1 in Open State within 5.0Å range: probe atom residue distance (Å) B Occ C:Na802 b:29.9 occ:1.00 NA A:NA803 4.2 1.9 1.0 CA C:GLY643 4.9 21.9 1.0

K.Zhang, D.Julius, Y.Cheng. Structural Snapshots of TRPV1 Reveal Mechanism of Polymodal Functionality. Cell 2021.
ISSN: ISSN 1097-4172
PubMed: 34496225
DOI: 10.1016/J.CELL.2021.08.012