Sodium in PDB 7e50: Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati

All present enzymatic activity of Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati:
3.4.21.7;

The structure of Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati, PDB code: 7e50 was solved by A.W.Varsha, C.Jobichen, Y.K.Mok, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.78 / 1.95
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	72.895, 86.044, 50.315, 90, 90, 90
R / Rfree (%)	21.8 / 27.5

The binding sites of Sodium atom in the Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati (pdb code 7e50). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati, PDB code: 7e50:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati within 5.0Å range: probe atom residue distance (Å) B Occ B:Na802 b:40.0 occ:1.00 O B:HOH948 2.6 34.7 1.0 O B:ILE705 2.7 32.6 1.0 OD1 B:ASN707 2.9 36.2 1.0 N B:CYS726 3.1 32.3 1.0 CB B:LEU725 3.3 34.7 1.0 O B:HOH960 3.3 39.4 1.0 CA B:LEU725 3.4 34.6 1.0 N B:ASN707 3.6 37.7 1.0 NH2 B:ARG776 3.6 37.3 1.0 CG1 B:VAL704 3.6 33.6 1.0 C B:ILE705 3.6 32.9 1.0 C B:LEU725 3.7 34.1 1.0 CA B:GLU706 3.7 35.1 1.0 O B:CYS726 3.9 32.1 1.0 C B:GLU706 3.9 34.6 1.0 CG B:ASN707 4.0 39.5 1.0 N B:GLU706 4.1 35.8 1.0 CA B:CYS726 4.2 31.4 1.0 CA B:ASN707 4.4 37.6 1.0 CB B:CYS726 4.4 29.5 1.0 C B:CYS726 4.5 31.2 1.0 CZ B:ARG776 4.5 37.6 1.0 CG B:LEU725 4.5 35.9 1.0 O B:HOH932 4.6 39.3 1.0 N B:ILE705 4.6 30.3 1.0 NH1 B:ARG776 4.7 36.9 1.0 N B:LEU725 4.7 32.9 1.0 O B:GLU724 4.8 35.2 1.0 CB B:ASN707 4.8 40.1 1.0 CD1 B:LEU725 4.8 32.0 1.0 CA B:ILE705 4.8 32.7 1.0 O B:GLU706 4.9 35.9 1.0 O B:LEU725 5.0 32.5 1.0

Sodium binding site 2 out of 3 in the Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati within 5.0Å range: probe atom residue distance (Å) B Occ B:Na803 b:47.6 occ:1.00 O B:HOH929 2.7 48.4 1.0 O B:ALA620 2.7 46.1 1.0 O B:HOH973 2.7 47.1 1.0 O B:HOH911 3.4 47.2 1.0 O B:TRP573 3.5 44.7 1.0 N B:ALA620 3.6 50.0 1.0 O B:HOH935 3.6 42.7 1.0 C B:ALA620 3.8 47.9 1.0 C B:GLY619 3.9 52.5 1.0 O B:HOH924 4.0 47.5 1.0 O B:GLN576 4.0 43.8 1.0 CA B:GLY619 4.1 50.9 1.0 CD2 B:LEU697 4.3 38.0 1.0 CB B:GLN576 4.3 39.3 1.0 C B:TRP573 4.3 44.8 1.0 CA B:ALA620 4.3 47.6 1.0 N B:GLY619 4.4 51.8 1.0 CD2 B:HIS571 4.4 49.6 1.0 CA B:PRO574 4.5 47.6 1.0 CA B:HIS571 4.5 45.8 1.0 O B:GLY619 4.6 53.4 1.0 C B:GLN576 4.8 43.6 1.0 CG B:GLN576 4.8 39.4 1.0 O B:LYS661 4.8 52.2 1.0 N B:PRO574 4.8 46.1 1.0 N B:GLN576 4.9 40.3 1.0 N B:HIS621 4.9 47.0 1.0 CH2 B:TRP685 4.9 40.1 1.0 CA B:GLN576 4.9 42.5 1.0 C B:PRO574 4.9 46.7 1.0 N B:HIS571 5.0 43.7 1.0

Sodium binding site 3 out of 3 in the Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati within 5.0Å range: probe atom residue distance (Å) B Occ B:Na804 b:35.3 occ:1.00 O3 B:GOL801 2.3 42.5 1.0 O B:HOH961 2.9 33.4 1.0 O B:GLY686 3.1 26.6 1.0 O B:TRP685 3.2 31.0 1.0 O B:HOH950 3.4 33.7 1.0 O B:HOH963 3.5 28.7 1.0 C3 B:GOL801 3.6 41.4 1.0 C B:GLY686 3.6 29.0 1.0 CA B:ALA694 3.8 37.2 1.0 CB B:ALA694 3.8 36.5 1.0 O2 B:GOL801 3.9 41.4 1.0 N B:GLY695 3.9 35.2 1.0 CA B:GLU687 4.1 32.0 1.0 N B:GLU687 4.1 28.7 1.0 C2 B:GOL801 4.1 39.8 1.0 C1 B:GOL801 4.2 39.9 1.0 OG1 B:THR688 4.2 35.5 1.0 C B:TRP685 4.2 31.8 1.0 C B:ALA694 4.3 36.8 1.0 N B:THR688 4.4 29.5 1.0 C B:GLU687 4.4 34.3 1.0 CA B:GLY686 4.6 28.7 1.0 CB B:THR688 4.6 37.8 1.0 O1 B:GOL801 4.6 44.8 1.0 OE1 B:GLU623 4.7 40.8 1.0 N B:GLY686 4.7 31.1 1.0 O B:HOH917 4.8 39.2 1.0

A.W.Varsha, C.Jobichen, Y.K.Mok. Crystal Structure of Human Microplasmin in Complex with Kazal-Type Inhibitor Aati To Be Published.