Sodium in PDB 6tlb: Plasmodium Falciparum Lipocalin (PF3D7_0925900)

The structure of Plasmodium Falciparum Lipocalin (PF3D7_0925900), PDB code: 6tlb was solved by P.C.Burda, T.D.Crosskey, K.Lauk, M.Wilmanns, T.W.Gilberger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.20 / 2.85
Space group	I 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	63.993, 92.250, 214.502, 90.00, 98.35, 90.00
R / Rfree (%)	18.9 / 23.6

The binding sites of Sodium atom in the Plasmodium Falciparum Lipocalin (PF3D7_0925900) (pdb code 6tlb). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Plasmodium Falciparum Lipocalin (PF3D7_0925900), PDB code: 6tlb:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in the Plasmodium Falciparum Lipocalin (PF3D7_0925900)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Plasmodium Falciparum Lipocalin (PF3D7_0925900) within 5.0Å range: probe atom residue distance (Å) B Occ B:Na401 b:20.0 occ:1.00 O B:CYS47 3.5 54.9 1.0 O B:GLN189 4.1 38.1 1.0 N B:ASP191 4.2 39.5 1.0 CG D:TRP184 4.2 60.0 1.0 CD2 D:TRP184 4.2 58.8 1.0 CE2 D:TRP184 4.3 57.2 1.0 CD1 D:TRP184 4.3 54.9 1.0 NE1 D:TRP184 4.4 53.1 1.0 CA B:THR190 4.4 39.8 1.0 CG2 B:ILE188 4.5 44.2 1.0 C B:CYS47 4.6 50.1 1.0 CE3 D:TRP184 4.7 59.5 1.0 CB D:TRP184 4.8 62.7 1.0 C B:THR190 4.8 38.8 1.0 NZ B:LYS40 4.8 60.2 1.0 CB B:ASP191 4.9 42.7 1.0 CZ2 D:TRP184 4.9 62.3 1.0 C B:GLN189 4.9 38.5 1.0

Sodium binding site 2 out of 3 in the Plasmodium Falciparum Lipocalin (PF3D7_0925900)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Plasmodium Falciparum Lipocalin (PF3D7_0925900) within 5.0Å range: probe atom residue distance (Å) B Occ D:Na303 b:20.0 occ:1.00 O D:CYS47 3.5 48.3 1.0 O D:GLN189 3.9 42.3 1.0 N D:ASP191 4.0 39.4 1.0 CD2 B:TRP184 4.1 54.6 1.0 CG B:TRP184 4.1 53.4 1.0 CA D:THR190 4.2 38.7 1.0 CE2 B:TRP184 4.3 52.7 1.0 CD1 B:TRP184 4.3 45.9 1.0 NE1 B:TRP184 4.4 46.6 1.0 CE3 B:TRP184 4.5 53.8 1.0 C D:THR190 4.6 38.9 1.0 C D:CYS47 4.6 45.3 1.0 CG2 D:ILE188 4.7 52.0 1.0 CB B:TRP184 4.7 62.2 1.0 CB D:ASP191 4.7 45.5 1.0 C D:GLN189 4.8 42.4 1.0 CZ2 B:TRP184 4.9 52.2 1.0 O3 D:GOL301 4.9 83.9 1.0 C3 D:GOL301 4.9 87.5 1.0 CA D:ASP191 5.0 41.1 1.0

Sodium binding site 3 out of 3 in the Plasmodium Falciparum Lipocalin (PF3D7_0925900)


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Plasmodium Falciparum Lipocalin (PF3D7_0925900) within 5.0Å range: probe atom residue distance (Å) B Occ D:Na304 b:20.0 occ:1.00 OH D:TYR110 3.7 55.7 1.0 OG D:SER108 4.2 43.6 1.0 OD1 D:ASN92 4.8 41.2 1.0 CB D:SER108 4.8 43.8 1.0 CZ D:TYR110 4.9 46.7 1.0

P.C.Burda, T.D.Crosskey, K.Lauk, A.Zurborg, C.Keil, B.Liffner, L.Wilcke, J.Strauss, C.Jeffries, D.Wilson, M.Wilmanns, T.W.Gilberger. Structural and Functional Analysis of An Essential Lipocalin in the Malaria Parasite Plasmodium Falciparum To Be Published.