Sodium »
PDB 6oor-6p8m »
6p1t »
Sodium in PDB 6p1t: Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp
Enzymatic activity of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp
All present enzymatic activity of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp, PDB code: 6p1t
was solved by
A.M.Kaminski,
L.C.Pedersen,
K.Bebenek,
K.K.Chiruvella,
D.A.Ramsden,
T.A.Kunkel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 43.04 / 1.70 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 59.805, 68.715, 110.434, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.9 / 19.1 |
Other elements in 6p1t:
The structure of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp also contains other interesting chemical elements:
| Magnesium | (Mg) | 2 atoms |
| Chlorine | (Cl) | 3 atoms |
Sodium Binding Sites:
The binding sites of Sodium atom in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp
(pdb code 6p1t). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp, PDB code: 6p1t:
Jump to Sodium binding site number: 1; 2;
In total 2 binding sites of Sodium where determined in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp, PDB code: 6p1t:
Jump to Sodium binding site number: 1; 2;
Sodium binding site 1 out of 2 in 6p1t
Go back to
Sodium Binding Sites List in 6p1t
Sodium binding site 1 out
of 2 in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp within 5.0Å range:
|
Sodium binding site 2 out of 2 in 6p1t
Go back to
Sodium Binding Sites List in 6p1t
Sodium binding site 2 out
of 2 in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Template 8OG and Bound Cmpcpp within 5.0Å range:
|
Reference:
A.M.Kaminski,
K.K.Chiruvella,
D.A.Ramsden,
T.A.Kunkel,
K.Bebenek,
L.C.Pedersen.
Unexpected Behavior of Dna Polymerase Mu Opposite Template 8-Oxo-7,8-Dihydro-2'-Guanosine. Nucleic Acids Res. V. 47 9410 2019.
ISSN: ESSN 1362-4962
PubMed: 31435651
DOI: 10.1093/NAR/GKZ680
Page generated: Tue Oct 8 12:39:59 2024
ISSN: ESSN 1362-4962
PubMed: 31435651
DOI: 10.1093/NAR/GKZ680
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
