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Sodium in PDB 6gn7: X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions.
Enzymatic activity of X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions.
All present enzymatic activity of X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions.:
3.4.21.5;
3.4.21.5;
Protein crystallography data
The structure of X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions., PDB code: 6gn7
was solved by
R.Troisi,
I.Russo Krauss,
F.Sica,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 104.51 / 2.80 |
| Space group | I 2 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 67.330, 120.690, 208.940, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 15.9 / 20.3 |
Sodium Binding Sites:
The binding sites of Sodium atom in the X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions.
(pdb code 6gn7). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions., PDB code: 6gn7:
Jump to Sodium binding site number: 1; 2;
In total 2 binding sites of Sodium where determined in the X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions., PDB code: 6gn7:
Jump to Sodium binding site number: 1; 2;
Sodium binding site 1 out of 2 in 6gn7
Go back to
Sodium Binding Sites List in 6gn7
Sodium binding site 1 out
of 2 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions. within 5.0Å range:
|
Sodium binding site 2 out of 2 in 6gn7
Go back to
Sodium Binding Sites List in 6gn7
Sodium binding site 2 out
of 2 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 2 of X-Ray Structure of the Complex Between Human Alpha Thrombin and NU172, A Duplex/Quadruplex 26-Mer Dna Aptamer, in the Presence of Sodium Ions. within 5.0Å range:
|
Reference:
R.Troisi,
V.Napolitano,
V.Spiridonova,
I.Russo Krauss,
F.Sica.
Several Structural Motifs Cooperate in Determining the Highly Effective Anti-Thrombin Activity of NU172 Aptamer. Nucleic Acids Res. V. 46 12177 2018.
ISSN: ESSN 1362-4962
PubMed: 30357392
DOI: 10.1093/NAR/GKY990
Page generated: Tue Dec 15 12:17:58 2020
ISSN: ESSN 1362-4962
PubMed: 30357392
DOI: 10.1093/NAR/GKY990
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