Atomistry » Sodium » PDB 6g3o-6gn6 » 6ghp
Atomistry »
  Sodium »
    PDB 6g3o-6gn6 »
      6ghp »

Sodium in PDB 6ghp: 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac

Protein crystallography data

The structure of 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac, PDB code: 6ghp was solved by S.A.Andrei, P.J.De Vink, L.Brunsveld, C.Ottmann, Y.Higuchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.61 / 1.95
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 82.453, 111.473, 63.675, 90.00, 90.00, 90.00
R / Rfree (%) 18.1 / 23.1

Other elements in 6ghp:

The structure of 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Sodium Binding Sites:

The binding sites of Sodium atom in the 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac (pdb code 6ghp). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac, PDB code: 6ghp:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in 6ghp

Go back to Sodium Binding Sites List in 6ghp
Sodium binding site 1 out of 2 in the 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na303

b:89.0
occ:1.00
OE2 A:GLU188 2.4 0.7 1.0
CD A:GLU188 3.3 0.9 1.0
HG2 A:GLU188 3.3 0.2 1.0
CG A:GLU188 3.8 98.5 1.0
OE1 A:GLU188 4.1 0.1 1.0
HG3 A:GLU188 4.3 0.2 1.0
O A:HOH442 4.9 42.2 1.0
HB3 A:GLU188 4.9 80.1 1.0

Sodium binding site 2 out of 2 in 6ghp

Go back to Sodium Binding Sites List in 6ghp
Sodium binding site 2 out of 2 in the 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of 14-3-3SIGMA in Complex with A TASK3 Peptide Stabilized By Semi- Synthetic Natural Product Fc-Nac within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na304

b:48.9
occ:1.00
OXT A:THR231 2.3 42.5 1.0
O A:HOH567 2.4 76.2 1.0
O A:THR228 2.5 29.1 1.0
O A:HOH541 2.6 55.8 1.0
C A:THR231 3.5 41.6 1.0
HG21 A:THR228 3.6 46.8 1.0
C A:THR228 3.7 32.0 1.0
HG23 A:THR228 4.1 46.8 1.0
O A:THR231 4.1 47.6 1.0
HA A:THR228 4.1 33.0 1.0
H A:THR231 4.1 50.0 1.0
HA A:LEU229 4.3 33.0 1.0
CG2 A:THR228 4.3 39.0 1.0
CA A:THR228 4.5 27.5 1.0
N A:THR231 4.6 41.6 1.0
O A:LEU229 4.6 27.5 1.0
CA A:THR231 4.7 36.1 1.0
N A:LEU229 4.7 28.1 1.0
C A:LEU229 4.7 31.8 1.0
CA A:LEU229 4.8 27.5 1.0
HG1 A:THR231 4.9 51.1 1.0

Reference:

S.A.Andrei, P.De Vink, E.Sijbesma, L.Han, L.Brunsveld, N.Kato, C.Ottmann, Y.Higuchi. Rationally Designed Semisynthetic Natural Product Analogues For Stabilization of 14-3-3 Protein-Protein Interactions. Angew. Chem. Int. Ed. Engl. V. 57 13470 2018.
ISSN: ESSN 1521-3773
PubMed: 30025189
DOI: 10.1002/ANIE.201806584
Page generated: Tue Dec 15 12:17:27 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy