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Atomistry » Sodium » PDB 6dmi-6e8s » 6dw4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 6dmi-6e8s » 6dw4 » |
Sodium in PDB 6dw4: SAMHD1 Bound to Cladribine-Tp in the Catalytic Pocket and Allosteric PocketProtein crystallography data
The structure of SAMHD1 Bound to Cladribine-Tp in the Catalytic Pocket and Allosteric Pocket, PDB code: 6dw4
was solved by
K.M.Knecht,
O.Buzovetsky,
C.Schneider,
D.Thomas,
V.Srikanth,
L.Kaderali,
F.Tofoleanu,
K.Reiss,
N.Ferreiros,
G.Geisslinger,
V.S.Batista,
X.Ji,
J.Cinatl,
O.T.Keppler,
Y.Xiong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6dw4:
The structure of SAMHD1 Bound to Cladribine-Tp in the Catalytic Pocket and Allosteric Pocket also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the SAMHD1 Bound to Cladribine-Tp in the Catalytic Pocket and Allosteric Pocket
(pdb code 6dw4). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the SAMHD1 Bound to Cladribine-Tp in the Catalytic Pocket and Allosteric Pocket, PDB code: 6dw4: Sodium binding site 1 out of 1 in 6dw4Go back to![]() ![]()
Sodium binding site 1 out
of 1 in the SAMHD1 Bound to Cladribine-Tp in the Catalytic Pocket and Allosteric Pocket
![]() Mono view ![]() Stereo pair view
Reference:
K.M.Knecht,
O.Buzovetsky,
C.Schneider,
D.Thomas,
V.Srikanth,
L.Kaderali,
F.Tofoleanu,
K.Reiss,
N.Ferreiros,
G.Geisslinger,
V.S.Batista,
X.Ji,
J.Cinatl Jr.,
O.T.Keppler,
Y.Xiong.
The Structural Basis For Cancer Drug Interactions with the Catalytic and Allosteric Sites of SAMHD1. Proc. Natl. Acad. Sci. V. 115 10022 2018U.S.A..
Page generated: Tue Dec 15 12:08:46 2020
ISSN: ESSN 1091-6490 PubMed: 30305425 DOI: 10.1073/PNAS.1805593115 |
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