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Sodium in PDB 6cpm: Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv
Enzymatic activity of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv
All present enzymatic activity of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv:
3.4.19.12;
3.4.19.12;
Protein crystallography data
The structure of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv, PDB code: 6cpm
was solved by
A.U.Singer,
J.Teyra,
G.Boehmelt,
M.Lenter,
F.Sicheri,
S.S.Sidhu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 38.21 / 2.01 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.552, 115.080, 95.701, 90.00, 92.59, 90.00 |
| R / Rfree (%) | 16.7 / 21.2 |
Other elements in 6cpm:
The structure of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv also contains other interesting chemical elements:
| Calcium | (Ca) | 5 atoms |
| Zinc | (Zn) | 2 atoms |
Sodium Binding Sites:
The binding sites of Sodium atom in the Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv
(pdb code 6cpm). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv, PDB code: 6cpm:
Jump to Sodium binding site number: 1; 2; 3;
In total 3 binding sites of Sodium where determined in the Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv, PDB code: 6cpm:
Jump to Sodium binding site number: 1; 2; 3;
Sodium binding site 1 out of 3 in 6cpm
Go back to
Sodium Binding Sites List in 6cpm
Sodium binding site 1 out
of 3 in the Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 1 of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv within 5.0Å range:
|
Sodium binding site 2 out of 3 in 6cpm
Go back to
Sodium Binding Sites List in 6cpm
Sodium binding site 2 out
of 3 in the Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 2 of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv within 5.0Å range:
|
Sodium binding site 3 out of 3 in 6cpm
Go back to
Sodium Binding Sites List in 6cpm
Sodium binding site 3 out
of 3 in the Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Sodium with other atoms in the Na binding
site number 3 of Structure of the USP15 Deubiquitinase Domain in Complex with A Third- Generation Inhibitory Ubv within 5.0Å range:
|
Reference:
J.Teyra,
A.U.Singer,
F.W.Schmitges,
P.Jaynes,
S.Kit Leng Lui,
M.J.Polyak,
N.Fodil,
J.R.Krieger,
J.Tong,
C.Schwerdtfeger,
B.B.Brasher,
D.F.J.Ceccarelli,
J.Moffat,
F.Sicheri,
M.F.Moran,
P.Gros,
P.J.A.Eichhorn,
M.Lenter,
G.Boehmelt,
S.S.Sidhu.
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure V. 27 590 2019.
ISSN: ISSN 1878-4186
PubMed: 30713027
DOI: 10.1016/J.STR.2019.01.002
Page generated: Tue Dec 15 12:04:41 2020
ISSN: ISSN 1878-4186
PubMed: 30713027
DOI: 10.1016/J.STR.2019.01.002
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