Sodium in PDB 6c96: Cryo-Em Structure of Mouse TPC1 Channel in the Apo State

The binding sites of Sodium atom in the Cryo-Em Structure of Mouse TPC1 Channel in the Apo State (pdb code 6c96). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Cryo-Em Structure of Mouse TPC1 Channel in the Apo State, PDB code: 6c96:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Cryo-Em Structure of Mouse TPC1 Channel in the Apo State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Cryo-Em Structure of Mouse TPC1 Channel in the Apo State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1004 b:48.5 occ:1.00 O B:THR280 4.1 48.1 1.0 O A:THR280 4.1 48.6 1.0 CB A:ASN648 4.3 47.5 1.0 CB B:ASN648 4.3 48.1 1.0 CG A:ASN648 4.5 47.5 1.0 CG B:ASN648 4.6 48.1 1.0 CA A:ASN648 4.6 47.5 1.0 N A:ASN648 4.6 47.5 1.0 CA B:ASN648 4.7 48.1 1.0 ND2 B:ASN648 4.8 48.1 1.0 ND2 A:ASN648 4.8 47.5 1.0 N B:ASN648 4.8 48.1 1.0 CB A:VAL647 4.9 44.6 1.0 OD1 A:ASN648 5.0 47.5 1.0

Sodium binding site 2 out of 2 in the Cryo-Em Structure of Mouse TPC1 Channel in the Apo State


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Cryo-Em Structure of Mouse TPC1 Channel in the Apo State within 5.0Å range: probe atom residue distance (Å) B Occ A:Na1005 b:46.4 occ:1.00 CD2 A:LEU317 4.8 50.0 1.0 CD2 B:LEU317 4.8 50.5 1.0

J.She, J.Guo, Q.Chen, W.Zeng, Y.Jiang, X.C.Bai. Structural Insights Into the Voltage and Phospholipid Activation of the Mammalian TPC1 Channel. Nature V. 556 130 2018.
ISSN: ESSN 1476-4687
PubMed: 29562233
DOI: 10.1038/NATURE26139