Sodium in PDB 5v0p: Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa

All present enzymatic activity of Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa:
2.3.1.180;

The structure of Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa, PDB code: 5v0p was solved by J.Hou, H.Zheng, D.R.Cooper, M.Grabowski, W.F.Anderson, W.Minor, Center Forstructural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 2.16
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	85.317, 61.887, 75.734, 90.00, 93.18, 90.00
R / Rfree (%)	17.4 / 20.7

The binding sites of Sodium atom in the Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa (pdb code 5v0p). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa, PDB code: 5v0p:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa within 5.0Å range: probe atom residue distance (Å) B Occ A:Na401 b:37.2 occ:1.00 O A:HOH649 2.3 39.4 1.0 O A:HOH609 2.3 31.4 1.0 O A:HOH615 2.4 46.2 1.0 OD2 A:ASP305 2.5 30.2 1.0 O A:GLU244 2.6 36.8 1.0 OD2 A:ASP246 2.7 31.3 1.0 CG A:ASP246 3.5 32.7 1.0 CG A:ASP305 3.5 28.8 1.0 O A:HOH652 3.6 53.9 1.0 OD1 A:ASP246 3.6 34.1 1.0 C A:GLU244 3.6 36.5 1.0 CB A:ASP305 3.8 28.6 1.0 N A:ASP305 4.0 28.7 1.0 CA A:GLU244 4.1 39.0 1.0 CB A:GLU244 4.2 40.8 1.0 NH1 A:ARG323 4.5 41.8 1.0 CA A:ASP305 4.6 28.1 1.0 OD1 A:ASP305 4.7 28.7 1.0 N A:ILE245 4.8 34.1 1.0 O A:HIS303 4.8 31.9 1.0 CB A:ASP246 4.9 32.5 1.0 C A:ASP304 4.9 28.5 1.0 N A:ASP246 4.9 31.8 1.0 CG A:GLU244 5.0 43.9 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa within 5.0Å range: probe atom residue distance (Å) B Occ B:Na401 b:35.1 occ:1.00 O B:HOH613 2.4 27.4 1.0 O B:HOH648 2.4 42.1 1.0 O B:HOH627 2.5 45.5 1.0 OD2 B:ASP305 2.5 28.9 1.0 O B:GLU244 2.6 35.6 1.0 OD2 B:ASP246 2.7 30.9 1.0 O B:HOH647 3.5 48.9 1.0 CG B:ASP305 3.5 27.3 1.0 CG B:ASP246 3.5 31.9 1.0 C B:GLU244 3.6 35.6 1.0 OD1 B:ASP246 3.7 32.4 1.0 CB B:ASP305 3.8 27.3 1.0 O B:HOH643 3.9 57.3 1.0 N B:ASP305 4.0 27.4 1.0 CA B:GLU244 4.1 38.4 1.0 CB B:GLU244 4.1 40.6 1.0 NH2 B:ARG323 4.3 43.8 1.0 O B:HOH671 4.6 58.8 1.0 CA B:ASP305 4.6 26.8 1.0 O B:HOH599 4.6 51.1 1.0 OD1 B:ASP305 4.6 27.6 1.0 N B:ILE245 4.8 33.4 1.0 O B:HIS303 4.9 31.0 1.0 CG B:GLU244 4.9 44.2 1.0 C B:ASP304 4.9 27.4 1.0 CB B:ASP246 4.9 32.0 1.0 N B:ASP246 5.0 31.4 1.0

J.Hou, H.Zheng, D.R.Cooper, M.Chruszcz, M.D.Chordia, M.Grabowski, W.Minor. Crystal Structure of Beta-Ketoacyl-Acp Synthase III-2 (FABH2) (C113A) From Vibrio Cholerae Co-Crystallized with Octanoyl-Coa To Be Published.