Sodium in PDB 5tek: Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis

All present enzymatic activity of Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis:
1.17.1.8;

The structure of Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis, PDB code: 5tek was solved by N.Mank, S.Pote, K.Arnette, V.Klapper, M.Chruszcz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.01
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	60.569, 122.607, 80.846, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 21.7

The structure of Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis also contains other interesting chemical elements:

Chlorine

(Cl)

3 atoms

The binding sites of Sodium atom in the Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis (pdb code 5tek). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis, PDB code: 5tek:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ A:Na302 b:70.7 occ:1.00 O A:LEU27 2.3 49.6 1.0 O A:ALA24 2.4 61.7 1.0 O A:ALA22 2.8 63.1 1.0 O A:VAL21 2.8 52.0 1.0 O A:HOH444 3.0 52.0 1.0 C A:ALA22 3.4 61.3 1.0 C A:LEU27 3.5 46.2 1.0 C A:ALA24 3.6 63.6 1.0 CA A:ALA22 3.8 57.0 1.0 C A:VAL21 3.9 49.0 1.0 N A:ALA24 4.1 63.3 1.0 N A:ALA22 4.3 53.2 1.0 CA A:ALA24 4.3 62.9 1.0 N A:THR28 4.4 45.7 1.0 CA A:THR28 4.4 45.4 1.0 N A:ALA23 4.4 63.3 1.0 CA A:LEU27 4.5 45.8 1.0 N A:LEU27 4.5 49.9 1.0 C A:ALA23 4.5 66.8 1.0 N A:ASP25 4.6 64.6 1.0 CA A:ASP25 4.7 66.3 1.0 CB A:LEU27 4.8 44.8 1.0 CB A:ALA24 4.9 60.9 1.0 C A:ASP25 4.9 63.0 1.0 O A:ALA23 4.9 71.0 1.0 CA A:ALA23 4.9 66.4 1.0 O A:ASP25 5.0 63.2 1.0

Sodium binding site 2 out of 2 in the Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Apo Structure of 4-Hydroxy-Tetrahydrodipicolinate Reductase From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ B:Na305 b:65.9 occ:1.00 O B:LEU27 2.3 47.5 1.0 O B:ALA24 2.3 57.0 1.0 O B:HOH486 2.3 71.8 1.0 O B:ALA22 2.7 60.0 1.0 O B:VAL21 2.8 49.0 1.0 O B:HOH470 3.4 51.5 1.0 C B:ALA22 3.4 53.8 1.0 C B:ALA24 3.5 59.7 1.0 C B:LEU27 3.5 44.5 1.0 CA B:ALA22 3.8 52.2 1.0 C B:VAL21 3.9 46.8 1.0 N B:ALA24 4.0 55.5 1.0 CA B:ALA24 4.2 57.1 1.0 N B:ALA22 4.3 47.8 1.0 C B:ALA23 4.4 57.9 1.0 N B:ALA23 4.4 54.2 1.0 N B:THR28 4.4 43.0 1.0 CA B:LEU27 4.4 45.4 1.0 N B:LEU27 4.4 47.8 1.0 O B:HOH414 4.4 68.8 1.0 CA B:THR28 4.4 43.4 1.0 N B:ASP25 4.5 63.9 1.0 CA B:ASP25 4.7 67.5 1.0 CB B:LEU27 4.7 42.3 1.0 CB B:ALA24 4.7 55.5 1.0 C B:ASP25 4.7 62.9 1.0 CA B:ALA23 4.9 57.3 1.0 O B:ALA23 4.9 60.4 1.0 O B:ASP25 4.9 65.3 1.0

M.Chruszcz, N.Mank, S.Pote, K.Arnette, V.Klapper, M.Chruszcz. N/A N/A.