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Atomistry » Sodium » PDB 5kd8-5kw9 » 5kj2 » |
Sodium in PDB 5kj2: The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate CancerEnzymatic activity of The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer
All present enzymatic activity of The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer:
2.3.1.48; Protein crystallography data
The structure of The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer, PDB code: 5kj2
was solved by
C.G.Jakob,
W.Qiu,
R.P.Edalji,
C.Sun,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5kj2:
The structure of The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer
(pdb code 5kj2). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer, PDB code: 5kj2: Sodium binding site 1 out of 1 in 5kj2Go back to Sodium Binding Sites List in 5kj2
Sodium binding site 1 out
of 1 in the The Novel P300/Cbp Inhibitor A-485 Uncovers A Unique Mechanism of Action to Target Ar in Castrate Resistant Prostate Cancer
Mono view Stereo pair view
Reference:
L.M.Lasko,
C.G.Jakob,
R.P.Edalji,
W.Qiu,
D.Montgomery,
E.L.Digiammarino,
T.M.Hansen,
R.M.Risi,
R.Frey,
V.Manaves,
B.Shaw,
M.Algire,
P.Hessler,
L.T.Lam,
T.Uziel,
E.Faivre,
D.Ferguson,
F.G.Buchanan,
R.L.Martin,
M.Torrent,
G.G.Chiang,
K.Karukurichi,
J.W.Langston,
B.T.Weinert,
C.Choudhary,
P.De Vries,
J.H.Van Drie,
D.Mcelligott,
E.Kesicki,
R.Marmorstein,
C.Sun,
P.A.Cole,
S.H.Rosenberg,
M.R.Michaelides,
A.Lai,
K.D.Bromberg.
Discovery of A Selective Catalytic P300/Cbp Inhibitor That Targets Lineage-Specific Tumours. Nature V. 550 128 2017.
Page generated: Tue Dec 15 11:10:25 2020
ISSN: ESSN 1476-4687 PubMed: 28953875 DOI: 10.1038/NATURE24028 |
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