Sodium in PDB 5isa: Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401

All present enzymatic activity of Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401:
2.1.1.319;

The structure of Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401, PDB code: 5isa was solved by V.Cura, N.Marechal, J.Mailliot, N.Troffer-Charlier, P.Hassenboehler, J.M.Wurtz, L.Bonnefond, J.Cavarelli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.71 / 2.40
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	74.541, 98.409, 205.803, 90.00, 90.00, 90.00
R / Rfree (%)	16.1 / 20.4

The binding sites of Sodium atom in the Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401 (pdb code 5isa). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401, PDB code: 5isa:

Sodium binding site 1 out of 1 in the Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na505 b:44.4 occ:1.00 HD12 B:ILE290 3.2 41.1 1.0 OD2 B:ASP292 3.2 43.4 1.0 OD1 B:ASP292 3.4 42.7 1.0 HZ3 B:LYS355 3.4 61.5 1.0 HH2 B:TRP404 3.4 28.3 1.0 HD3 B:LYS355 3.5 52.9 1.0 HD11 B:ILE290 3.6 41.1 1.0 HD13 B:ILE290 3.6 41.1 1.0 HG21 B:THR357 3.6 30.7 1.0 CD1 B:ILE290 3.6 34.2 1.0 HG1 B:THR357 3.6 38.9 1.0 CG B:ASP292 3.7 40.6 1.0 OG1 B:THR357 3.8 32.4 1.0 HG23 B:THR357 4.1 30.7 1.0 NZ B:LYS355 4.2 51.2 1.0 CG2 B:THR357 4.2 25.6 1.0 CD B:LYS355 4.3 44.1 1.0 CH2 B:TRP404 4.3 23.6 1.0 HZ2 B:LYS355 4.3 61.5 1.0 HD2 B:LYS355 4.5 52.9 1.0 CB B:THR357 4.7 25.3 1.0 CE B:LYS355 4.8 48.2 1.0 HZ1 B:LYS355 4.8 61.5 1.0 HZ2 B:TRP404 4.8 24.6 1.0 HE2 B:LYS355 4.9 57.9 1.0

V.Cura, N.Marechal, J.Mailliot, N.Troffer-Charlier, J.M.Wurtz, L.Bonnefond, J.Cavarelli. Crystal Structure of Mouse CARM1 in Complex with Inhibitor SA0401 To Be Published.