Sodium in PDB 5epu: X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.
Enzymatic activity of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.
All present enzymatic activity of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.:
2.4.2.3;
Protein crystallography data
The structure of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A., PDB code: 5epu
was solved by
I.I.Prokofev,
A.A.Lashkov,
A.G.Gabdoulkhakov,
C.Betzel,
A.M.Mikhailov,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
46.46 /
1.06
|
Space group
|
P 1 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
92.848,
96.715,
92.890,
90.00,
119.96,
90.00
|
R / Rfree (%)
|
10.5 /
12.2
|
Other elements in 5epu:
The structure of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.
(pdb code 5epu). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the
X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A., PDB code: 5epu:
Jump to Sodium binding site number:
1;
2;
3;
Sodium binding site 1 out
of 3 in 5epu
Go back to
Sodium Binding Sites List in 5epu
Sodium binding site 1 out
of 3 in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 1 of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Na306
b:8.4
occ:0.52
|
HG
|
B:SER72
|
2.3
|
4.9
|
0.0
|
HG
|
A:SER72
|
2.3
|
4.2
|
0.0
|
HB2
|
B:SER72
|
2.6
|
6.0
|
0.3
|
HB2
|
A:SER72
|
2.6
|
6.2
|
0.3
|
OE1
|
B:GLU48
|
2.7
|
9.9
|
1.0
|
HG
|
B:SER72
|
2.7
|
7.9
|
0.0
|
OE2
|
A:GLU48
|
2.7
|
9.1
|
1.0
|
HG
|
A:SER72
|
2.8
|
8.4
|
0.0
|
O
|
A:ILE68
|
2.9
|
6.4
|
1.0
|
OG
|
A:SER72
|
2.9
|
4.1
|
0.7
|
OG
|
B:SER72
|
2.9
|
4.8
|
0.7
|
HB3
|
A:SER72
|
3.0
|
4.5
|
0.7
|
O
|
B:ILE68
|
3.0
|
6.2
|
1.0
|
HB3
|
B:SER72
|
3.0
|
5.2
|
0.7
|
H
|
B:ILE68
|
3.1
|
6.1
|
1.0
|
H
|
A:ILE68
|
3.1
|
6.0
|
1.0
|
CB
|
A:SER72
|
3.2
|
6.4
|
0.3
|
OG
|
B:SER72
|
3.2
|
7.9
|
0.3
|
CB
|
B:SER72
|
3.2
|
6.2
|
0.3
|
OG
|
A:SER72
|
3.3
|
8.7
|
0.3
|
HA3
|
B:GLY67
|
3.3
|
7.0
|
1.0
|
HB3
|
A:SER72
|
3.3
|
6.4
|
0.3
|
HA3
|
A:GLY67
|
3.4
|
7.1
|
1.0
|
CB
|
A:SER72
|
3.4
|
4.3
|
0.7
|
CB
|
B:SER72
|
3.4
|
5.2
|
0.7
|
HB3
|
B:SER72
|
3.5
|
6.2
|
0.3
|
N
|
B:ILE68
|
3.6
|
6.0
|
1.0
|
N
|
A:ILE68
|
3.6
|
6.5
|
1.0
|
O
|
A:HOH499
|
3.7
|
5.8
|
0.5
|
O
|
A:HOH499
|
3.7
|
5.8
|
0.5
|
HB2
|
A:SER72
|
3.7
|
4.7
|
0.7
|
HB2
|
B:SER72
|
3.7
|
5.3
|
0.7
|
CD
|
B:GLU48
|
3.8
|
10.1
|
1.0
|
CD
|
A:GLU48
|
3.9
|
10.0
|
1.0
|
HG3
|
A:GLU48
|
3.9
|
10.1
|
1.0
|
HG3
|
B:GLU48
|
3.9
|
11.1
|
1.0
|
C
|
A:ILE68
|
3.9
|
5.2
|
1.0
|
C
|
B:ILE68
|
3.9
|
5.2
|
1.0
|
HB
|
B:ILE68
|
4.1
|
6.4
|
1.0
|
HB
|
A:ILE68
|
4.1
|
7.0
|
1.0
|
CA
|
B:GLY67
|
4.1
|
6.9
|
1.0
|
CA
|
A:GLY67
|
4.1
|
6.9
|
1.0
|
C
|
B:GLY67
|
4.1
|
6.1
|
1.0
|
C
|
A:GLY67
|
4.2
|
6.1
|
1.0
|
CA
|
A:ILE68
|
4.2
|
5.9
|
1.0
|
CA
|
B:ILE68
|
4.3
|
5.7
|
1.0
|
CG
|
B:GLU48
|
4.4
|
11.1
|
1.0
|
CG
|
A:GLU48
|
4.4
|
10.7
|
1.0
|
HA2
|
B:GLY67
|
4.4
|
7.4
|
1.0
|
H
|
A:SER72
|
4.4
|
4.8
|
1.0
|
HA2
|
A:GLY67
|
4.5
|
7.1
|
1.0
|
H
|
B:SER72
|
4.5
|
5.1
|
1.0
|
CA
|
B:SER72
|
4.6
|
5.6
|
0.3
|
CA
|
A:SER72
|
4.6
|
5.4
|
0.3
|
CB
|
A:ILE68
|
4.7
|
6.8
|
1.0
|
CB
|
B:ILE68
|
4.7
|
6.3
|
1.0
|
HB3
|
B:GLU48
|
4.7
|
10.4
|
1.0
|
HB3
|
A:GLU48
|
4.7
|
10.2
|
1.0
|
CA
|
A:SER72
|
4.7
|
4.7
|
0.7
|
CA
|
B:SER72
|
4.8
|
5.5
|
0.7
|
O
|
A:THR66
|
4.8
|
7.4
|
1.0
|
O
|
B:THR66
|
4.8
|
7.7
|
1.0
|
HA
|
B:SER72
|
4.8
|
5.6
|
0.3
|
OE2
|
B:GLU48
|
4.8
|
13.5
|
1.0
|
OE1
|
A:GLU48
|
4.9
|
12.6
|
1.0
|
HA
|
A:SER72
|
4.9
|
5.3
|
0.3
|
N
|
A:SER72
|
5.0
|
4.7
|
1.0
|
N
|
B:SER72
|
5.0
|
4.9
|
1.0
|
|
Sodium binding site 2 out
of 3 in 5epu
Go back to
Sodium Binding Sites List in 5epu
Sodium binding site 2 out
of 3 in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 2 of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Na304
b:8.9
occ:0.55
|
HG
|
C:SER72
|
2.3
|
4.6
|
0.0
|
HG
|
D:SER72
|
2.3
|
4.3
|
0.0
|
HB2
|
D:SER72
|
2.6
|
5.7
|
0.3
|
HB2
|
C:SER72
|
2.6
|
5.8
|
0.3
|
HG
|
D:SER72
|
2.7
|
6.8
|
0.0
|
OE2
|
D:GLU48
|
2.7
|
9.0
|
1.0
|
OE2
|
C:GLU48
|
2.7
|
9.4
|
1.0
|
HG
|
C:SER72
|
2.8
|
7.6
|
0.0
|
OG
|
C:SER72
|
2.9
|
4.5
|
0.7
|
OG
|
D:SER72
|
2.9
|
4.2
|
0.7
|
HB3
|
D:SER72
|
3.0
|
4.5
|
0.7
|
O
|
C:ILE68
|
3.0
|
6.2
|
1.0
|
O
|
D:ILE68
|
3.0
|
6.1
|
1.0
|
HB3
|
C:SER72
|
3.0
|
4.8
|
0.7
|
H
|
C:ILE68
|
3.1
|
6.1
|
1.0
|
H
|
D:ILE68
|
3.2
|
5.4
|
1.0
|
OG
|
D:SER72
|
3.2
|
6.9
|
0.3
|
CB
|
D:SER72
|
3.2
|
5.7
|
0.3
|
CB
|
C:SER72
|
3.2
|
5.9
|
0.3
|
OG
|
C:SER72
|
3.3
|
7.6
|
0.3
|
HA3
|
C:GLY67
|
3.3
|
6.4
|
1.0
|
HA3
|
D:GLY67
|
3.4
|
6.6
|
1.0
|
CB
|
D:SER72
|
3.4
|
4.3
|
0.7
|
HB3
|
C:SER72
|
3.4
|
6.0
|
0.3
|
CB
|
C:SER72
|
3.4
|
4.7
|
0.7
|
HB3
|
D:SER72
|
3.4
|
5.8
|
0.3
|
N
|
C:ILE68
|
3.5
|
6.0
|
1.0
|
N
|
D:ILE68
|
3.6
|
5.7
|
1.0
|
O
|
D:HOH492
|
3.7
|
5.8
|
0.5
|
O
|
D:HOH492
|
3.7
|
5.3
|
0.5
|
HB2
|
D:SER72
|
3.7
|
4.6
|
0.7
|
HB2
|
C:SER72
|
3.8
|
4.8
|
0.7
|
CD
|
D:GLU48
|
3.8
|
10.3
|
1.0
|
HG3
|
D:GLU48
|
3.8
|
10.0
|
1.0
|
HG3
|
C:GLU48
|
3.8
|
9.9
|
1.0
|
CD
|
C:GLU48
|
3.8
|
9.7
|
1.0
|
C
|
C:ILE68
|
3.9
|
5.0
|
1.0
|
C
|
D:ILE68
|
3.9
|
5.0
|
1.0
|
HB
|
C:ILE68
|
4.0
|
6.4
|
1.0
|
HB
|
D:ILE68
|
4.0
|
6.5
|
1.0
|
CA
|
C:GLY67
|
4.1
|
6.4
|
1.0
|
C
|
C:GLY67
|
4.1
|
5.9
|
1.0
|
CA
|
D:GLY67
|
4.1
|
6.4
|
1.0
|
C
|
D:GLY67
|
4.2
|
6.1
|
1.0
|
CA
|
C:ILE68
|
4.2
|
5.6
|
1.0
|
CA
|
D:ILE68
|
4.3
|
5.4
|
1.0
|
CG
|
D:GLU48
|
4.3
|
10.7
|
1.0
|
CG
|
C:GLU48
|
4.3
|
9.9
|
1.0
|
HA2
|
C:GLY67
|
4.4
|
7.0
|
1.0
|
HA2
|
D:GLY67
|
4.4
|
6.4
|
1.0
|
H
|
C:SER72
|
4.5
|
4.7
|
1.0
|
H
|
D:SER72
|
4.5
|
4.6
|
1.0
|
CA
|
D:SER72
|
4.6
|
5.3
|
0.3
|
CA
|
C:SER72
|
4.6
|
5.5
|
0.3
|
CB
|
C:ILE68
|
4.7
|
6.4
|
1.0
|
HB3
|
C:GLU48
|
4.7
|
9.4
|
1.0
|
CB
|
D:ILE68
|
4.7
|
6.3
|
1.0
|
CA
|
D:SER72
|
4.7
|
4.7
|
0.7
|
CA
|
C:SER72
|
4.8
|
5.2
|
0.7
|
HB3
|
D:GLU48
|
4.8
|
9.7
|
1.0
|
O
|
C:THR66
|
4.8
|
7.4
|
1.0
|
OE1
|
D:GLU48
|
4.8
|
13.6
|
1.0
|
O
|
D:THR66
|
4.8
|
7.4
|
1.0
|
HA
|
D:SER72
|
4.8
|
5.1
|
0.3
|
OE1
|
C:GLU48
|
4.9
|
11.6
|
1.0
|
HA
|
C:SER72
|
4.9
|
5.2
|
0.3
|
N
|
D:SER72
|
5.0
|
4.5
|
1.0
|
N
|
C:SER72
|
5.0
|
4.6
|
1.0
|
CB
|
C:GLU48
|
5.0
|
9.8
|
1.0
|
|
Sodium binding site 3 out
of 3 in 5epu
Go back to
Sodium Binding Sites List in 5epu
Sodium binding site 3 out
of 3 in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.
Mono view
Stereo pair view
|
A full contact list of Sodium with other atoms in the Na binding
site number 3 of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Na306
b:7.6
occ:0.54
|
HG
|
F:SER72
|
2.3
|
4.4
|
0.0
|
HG
|
E:SER72
|
2.3
|
4.3
|
0.0
|
HB2
|
F:SER72
|
2.6
|
5.0
|
0.2
|
HB2
|
E:SER72
|
2.6
|
5.5
|
0.3
|
OE2
|
F:GLU48
|
2.7
|
9.1
|
1.0
|
HG
|
F:SER72
|
2.7
|
5.2
|
0.0
|
OE2
|
E:GLU48
|
2.7
|
9.0
|
1.0
|
HG
|
E:SER72
|
2.8
|
6.9
|
0.0
|
OG
|
E:SER72
|
2.9
|
4.1
|
0.7
|
OG
|
F:SER72
|
2.9
|
4.4
|
0.8
|
O
|
F:ILE68
|
2.9
|
5.5
|
1.0
|
O
|
E:ILE68
|
3.0
|
5.7
|
1.0
|
HB3
|
F:SER72
|
3.0
|
5.2
|
0.8
|
HB3
|
E:SER72
|
3.0
|
4.8
|
0.7
|
H
|
F:ILE68
|
3.1
|
5.2
|
1.0
|
H
|
E:ILE68
|
3.1
|
5.4
|
1.0
|
CB
|
F:SER72
|
3.2
|
4.5
|
0.2
|
OG
|
F:SER72
|
3.2
|
5.0
|
0.2
|
CB
|
E:SER72
|
3.2
|
5.4
|
0.3
|
OG
|
E:SER72
|
3.3
|
6.9
|
0.3
|
HA3
|
F:GLY67
|
3.3
|
6.7
|
1.0
|
HA3
|
E:GLY67
|
3.4
|
6.5
|
1.0
|
CB
|
F:SER72
|
3.4
|
4.8
|
0.8
|
CB
|
E:SER72
|
3.4
|
4.4
|
0.7
|
HB3
|
E:SER72
|
3.4
|
5.6
|
0.3
|
HB3
|
F:SER72
|
3.4
|
4.7
|
0.2
|
N
|
F:ILE68
|
3.6
|
5.2
|
1.0
|
N
|
E:ILE68
|
3.6
|
5.3
|
1.0
|
O
|
E:HOH478
|
3.7
|
5.0
|
0.5
|
O
|
E:HOH478
|
3.7
|
5.5
|
0.5
|
HB2
|
F:SER72
|
3.7
|
4.7
|
0.8
|
HB2
|
E:SER72
|
3.7
|
4.4
|
0.7
|
HG3
|
F:GLU48
|
3.8
|
9.7
|
1.0
|
CD
|
F:GLU48
|
3.8
|
9.7
|
1.0
|
HG3
|
E:GLU48
|
3.8
|
8.9
|
1.0
|
CD
|
E:GLU48
|
3.8
|
9.0
|
1.0
|
C
|
F:ILE68
|
3.9
|
4.6
|
1.0
|
C
|
E:ILE68
|
3.9
|
4.8
|
1.0
|
HB
|
F:ILE68
|
4.0
|
6.2
|
1.0
|
HB
|
E:ILE68
|
4.0
|
6.5
|
1.0
|
CA
|
F:GLY67
|
4.1
|
6.1
|
1.0
|
CA
|
E:GLY67
|
4.1
|
6.0
|
1.0
|
C
|
F:GLY67
|
4.2
|
5.2
|
1.0
|
C
|
E:GLY67
|
4.2
|
4.9
|
1.0
|
CA
|
F:ILE68
|
4.2
|
5.0
|
1.0
|
CA
|
E:ILE68
|
4.2
|
5.2
|
1.0
|
CG
|
F:GLU48
|
4.3
|
10.3
|
1.0
|
CG
|
E:GLU48
|
4.3
|
9.5
|
1.0
|
HA2
|
F:GLY67
|
4.4
|
6.1
|
1.0
|
HA2
|
E:GLY67
|
4.4
|
6.0
|
1.0
|
H
|
E:SER72
|
4.4
|
4.6
|
1.0
|
H
|
F:SER72
|
4.4
|
4.5
|
1.0
|
CA
|
F:SER72
|
4.6
|
4.8
|
0.2
|
CA
|
E:SER72
|
4.6
|
5.2
|
0.3
|
CB
|
F:ILE68
|
4.7
|
5.8
|
1.0
|
HB3
|
E:GLU48
|
4.7
|
9.5
|
1.0
|
CB
|
E:ILE68
|
4.7
|
5.9
|
1.0
|
HB3
|
F:GLU48
|
4.7
|
9.6
|
1.0
|
CA
|
F:SER72
|
4.7
|
4.7
|
0.8
|
CA
|
E:SER72
|
4.7
|
4.7
|
0.7
|
O
|
F:THR66
|
4.8
|
6.6
|
1.0
|
HA
|
F:SER72
|
4.8
|
4.6
|
0.2
|
OE1
|
F:GLU48
|
4.9
|
12.8
|
1.0
|
O
|
E:THR66
|
4.9
|
6.8
|
1.0
|
OE1
|
E:GLU48
|
4.9
|
11.8
|
1.0
|
HA
|
E:SER72
|
4.9
|
5.2
|
0.3
|
N
|
F:SER72
|
5.0
|
4.4
|
1.0
|
N
|
E:SER72
|
5.0
|
4.6
|
1.0
|
CB
|
E:GLU48
|
5.0
|
9.7
|
1.0
|
|
Reference:
I.I.Prokofev,
A.A.Lashkov,
A.G.Gabdoulkhakov,
C.Betzel,
A.M.Mikhailov.
X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. To Be Published.
Page generated: Mon Oct 7 20:50:41 2024
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