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Sodium in PDB 5epu: X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.

Enzymatic activity of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.

All present enzymatic activity of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.:
2.4.2.3;

Protein crystallography data

The structure of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A., PDB code: 5epu was solved by I.I.Prokofev, A.A.Lashkov, A.G.Gabdoulkhakov, C.Betzel, A.M.Mikhailov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.46 / 1.06
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 92.848, 96.715, 92.890, 90.00, 119.96, 90.00
R / Rfree (%) 10.5 / 12.2

Other elements in 5epu:

The structure of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. also contains other interesting chemical elements:

Magnesium (Mg) 7 atoms
Chlorine (Cl) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. (pdb code 5epu). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A., PDB code: 5epu:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in 5epu

Go back to Sodium Binding Sites List in 5epu
Sodium binding site 1 out of 3 in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na306

b:8.4
occ:0.52
HG B:SER72 2.3 4.9 0.0
HG A:SER72 2.3 4.2 0.0
HB2 B:SER72 2.6 6.0 0.3
HB2 A:SER72 2.6 6.2 0.3
OE1 B:GLU48 2.7 9.9 1.0
HG B:SER72 2.7 7.9 0.0
OE2 A:GLU48 2.7 9.1 1.0
HG A:SER72 2.8 8.4 0.0
O A:ILE68 2.9 6.4 1.0
OG A:SER72 2.9 4.1 0.7
OG B:SER72 2.9 4.8 0.7
HB3 A:SER72 3.0 4.5 0.7
O B:ILE68 3.0 6.2 1.0
HB3 B:SER72 3.0 5.2 0.7
H B:ILE68 3.1 6.1 1.0
H A:ILE68 3.1 6.0 1.0
CB A:SER72 3.2 6.4 0.3
OG B:SER72 3.2 7.9 0.3
CB B:SER72 3.2 6.2 0.3
OG A:SER72 3.3 8.7 0.3
HA3 B:GLY67 3.3 7.0 1.0
HB3 A:SER72 3.3 6.4 0.3
HA3 A:GLY67 3.4 7.1 1.0
CB A:SER72 3.4 4.3 0.7
CB B:SER72 3.4 5.2 0.7
HB3 B:SER72 3.5 6.2 0.3
N B:ILE68 3.6 6.0 1.0
N A:ILE68 3.6 6.5 1.0
O A:HOH499 3.7 5.8 0.5
O A:HOH499 3.7 5.8 0.5
HB2 A:SER72 3.7 4.7 0.7
HB2 B:SER72 3.7 5.3 0.7
CD B:GLU48 3.8 10.1 1.0
CD A:GLU48 3.9 10.0 1.0
HG3 A:GLU48 3.9 10.1 1.0
HG3 B:GLU48 3.9 11.1 1.0
C A:ILE68 3.9 5.2 1.0
C B:ILE68 3.9 5.2 1.0
HB B:ILE68 4.1 6.4 1.0
HB A:ILE68 4.1 7.0 1.0
CA B:GLY67 4.1 6.9 1.0
CA A:GLY67 4.1 6.9 1.0
C B:GLY67 4.1 6.1 1.0
C A:GLY67 4.2 6.1 1.0
CA A:ILE68 4.2 5.9 1.0
CA B:ILE68 4.3 5.7 1.0
CG B:GLU48 4.4 11.1 1.0
CG A:GLU48 4.4 10.7 1.0
HA2 B:GLY67 4.4 7.4 1.0
H A:SER72 4.4 4.8 1.0
HA2 A:GLY67 4.5 7.1 1.0
H B:SER72 4.5 5.1 1.0
CA B:SER72 4.6 5.6 0.3
CA A:SER72 4.6 5.4 0.3
CB A:ILE68 4.7 6.8 1.0
CB B:ILE68 4.7 6.3 1.0
HB3 B:GLU48 4.7 10.4 1.0
HB3 A:GLU48 4.7 10.2 1.0
CA A:SER72 4.7 4.7 0.7
CA B:SER72 4.8 5.5 0.7
O A:THR66 4.8 7.4 1.0
O B:THR66 4.8 7.7 1.0
HA B:SER72 4.8 5.6 0.3
OE2 B:GLU48 4.8 13.5 1.0
OE1 A:GLU48 4.9 12.6 1.0
HA A:SER72 4.9 5.3 0.3
N A:SER72 5.0 4.7 1.0
N B:SER72 5.0 4.9 1.0

Sodium binding site 2 out of 3 in 5epu

Go back to Sodium Binding Sites List in 5epu
Sodium binding site 2 out of 3 in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na304

b:8.9
occ:0.55
HG C:SER72 2.3 4.6 0.0
HG D:SER72 2.3 4.3 0.0
HB2 D:SER72 2.6 5.7 0.3
HB2 C:SER72 2.6 5.8 0.3
HG D:SER72 2.7 6.8 0.0
OE2 D:GLU48 2.7 9.0 1.0
OE2 C:GLU48 2.7 9.4 1.0
HG C:SER72 2.8 7.6 0.0
OG C:SER72 2.9 4.5 0.7
OG D:SER72 2.9 4.2 0.7
HB3 D:SER72 3.0 4.5 0.7
O C:ILE68 3.0 6.2 1.0
O D:ILE68 3.0 6.1 1.0
HB3 C:SER72 3.0 4.8 0.7
H C:ILE68 3.1 6.1 1.0
H D:ILE68 3.2 5.4 1.0
OG D:SER72 3.2 6.9 0.3
CB D:SER72 3.2 5.7 0.3
CB C:SER72 3.2 5.9 0.3
OG C:SER72 3.3 7.6 0.3
HA3 C:GLY67 3.3 6.4 1.0
HA3 D:GLY67 3.4 6.6 1.0
CB D:SER72 3.4 4.3 0.7
HB3 C:SER72 3.4 6.0 0.3
CB C:SER72 3.4 4.7 0.7
HB3 D:SER72 3.4 5.8 0.3
N C:ILE68 3.5 6.0 1.0
N D:ILE68 3.6 5.7 1.0
O D:HOH492 3.7 5.8 0.5
O D:HOH492 3.7 5.3 0.5
HB2 D:SER72 3.7 4.6 0.7
HB2 C:SER72 3.8 4.8 0.7
CD D:GLU48 3.8 10.3 1.0
HG3 D:GLU48 3.8 10.0 1.0
HG3 C:GLU48 3.8 9.9 1.0
CD C:GLU48 3.8 9.7 1.0
C C:ILE68 3.9 5.0 1.0
C D:ILE68 3.9 5.0 1.0
HB C:ILE68 4.0 6.4 1.0
HB D:ILE68 4.0 6.5 1.0
CA C:GLY67 4.1 6.4 1.0
C C:GLY67 4.1 5.9 1.0
CA D:GLY67 4.1 6.4 1.0
C D:GLY67 4.2 6.1 1.0
CA C:ILE68 4.2 5.6 1.0
CA D:ILE68 4.3 5.4 1.0
CG D:GLU48 4.3 10.7 1.0
CG C:GLU48 4.3 9.9 1.0
HA2 C:GLY67 4.4 7.0 1.0
HA2 D:GLY67 4.4 6.4 1.0
H C:SER72 4.5 4.7 1.0
H D:SER72 4.5 4.6 1.0
CA D:SER72 4.6 5.3 0.3
CA C:SER72 4.6 5.5 0.3
CB C:ILE68 4.7 6.4 1.0
HB3 C:GLU48 4.7 9.4 1.0
CB D:ILE68 4.7 6.3 1.0
CA D:SER72 4.7 4.7 0.7
CA C:SER72 4.8 5.2 0.7
HB3 D:GLU48 4.8 9.7 1.0
O C:THR66 4.8 7.4 1.0
OE1 D:GLU48 4.8 13.6 1.0
O D:THR66 4.8 7.4 1.0
HA D:SER72 4.8 5.1 0.3
OE1 C:GLU48 4.9 11.6 1.0
HA C:SER72 4.9 5.2 0.3
N D:SER72 5.0 4.5 1.0
N C:SER72 5.0 4.6 1.0
CB C:GLU48 5.0 9.8 1.0

Sodium binding site 3 out of 3 in 5epu

Go back to Sodium Binding Sites List in 5epu
Sodium binding site 3 out of 3 in the X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A.


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Na306

b:7.6
occ:0.54
HG F:SER72 2.3 4.4 0.0
HG E:SER72 2.3 4.3 0.0
HB2 F:SER72 2.6 5.0 0.2
HB2 E:SER72 2.6 5.5 0.3
OE2 F:GLU48 2.7 9.1 1.0
HG F:SER72 2.7 5.2 0.0
OE2 E:GLU48 2.7 9.0 1.0
HG E:SER72 2.8 6.9 0.0
OG E:SER72 2.9 4.1 0.7
OG F:SER72 2.9 4.4 0.8
O F:ILE68 2.9 5.5 1.0
O E:ILE68 3.0 5.7 1.0
HB3 F:SER72 3.0 5.2 0.8
HB3 E:SER72 3.0 4.8 0.7
H F:ILE68 3.1 5.2 1.0
H E:ILE68 3.1 5.4 1.0
CB F:SER72 3.2 4.5 0.2
OG F:SER72 3.2 5.0 0.2
CB E:SER72 3.2 5.4 0.3
OG E:SER72 3.3 6.9 0.3
HA3 F:GLY67 3.3 6.7 1.0
HA3 E:GLY67 3.4 6.5 1.0
CB F:SER72 3.4 4.8 0.8
CB E:SER72 3.4 4.4 0.7
HB3 E:SER72 3.4 5.6 0.3
HB3 F:SER72 3.4 4.7 0.2
N F:ILE68 3.6 5.2 1.0
N E:ILE68 3.6 5.3 1.0
O E:HOH478 3.7 5.0 0.5
O E:HOH478 3.7 5.5 0.5
HB2 F:SER72 3.7 4.7 0.8
HB2 E:SER72 3.7 4.4 0.7
HG3 F:GLU48 3.8 9.7 1.0
CD F:GLU48 3.8 9.7 1.0
HG3 E:GLU48 3.8 8.9 1.0
CD E:GLU48 3.8 9.0 1.0
C F:ILE68 3.9 4.6 1.0
C E:ILE68 3.9 4.8 1.0
HB F:ILE68 4.0 6.2 1.0
HB E:ILE68 4.0 6.5 1.0
CA F:GLY67 4.1 6.1 1.0
CA E:GLY67 4.1 6.0 1.0
C F:GLY67 4.2 5.2 1.0
C E:GLY67 4.2 4.9 1.0
CA F:ILE68 4.2 5.0 1.0
CA E:ILE68 4.2 5.2 1.0
CG F:GLU48 4.3 10.3 1.0
CG E:GLU48 4.3 9.5 1.0
HA2 F:GLY67 4.4 6.1 1.0
HA2 E:GLY67 4.4 6.0 1.0
H E:SER72 4.4 4.6 1.0
H F:SER72 4.4 4.5 1.0
CA F:SER72 4.6 4.8 0.2
CA E:SER72 4.6 5.2 0.3
CB F:ILE68 4.7 5.8 1.0
HB3 E:GLU48 4.7 9.5 1.0
CB E:ILE68 4.7 5.9 1.0
HB3 F:GLU48 4.7 9.6 1.0
CA F:SER72 4.7 4.7 0.8
CA E:SER72 4.7 4.7 0.7
O F:THR66 4.8 6.6 1.0
HA F:SER72 4.8 4.6 0.2
OE1 F:GLU48 4.9 12.8 1.0
O E:THR66 4.9 6.8 1.0
OE1 E:GLU48 4.9 11.8 1.0
HA E:SER72 4.9 5.2 0.3
N F:SER72 5.0 4.4 1.0
N E:SER72 5.0 4.6 1.0
CB E:GLU48 5.0 9.7 1.0

Reference:

I.I.Prokofev, A.A.Lashkov, A.G.Gabdoulkhakov, C.Betzel, A.M.Mikhailov. X-Ray Structure Uridine Phosphorylase From Vibrio Cholerae in Complex with Cytosine at 1.06A. To Be Published.
Page generated: Mon Oct 7 20:50:41 2024

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