Atomistry » Sodium » PDB 5cd1-5cwl » 5coq
Atomistry »
  Sodium »
    PDB 5cd1-5cwl »
      5coq »

Sodium in PDB 5coq: The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility

Enzymatic activity of The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility

All present enzymatic activity of The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility:
1.3.1.9;

Protein crystallography data

The structure of The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility, PDB code: 5coq was solved by H.-J.Li, C.-T.Lai, N.Liu, W.Yu, S.Shah, G.R.Bommineni, V.Perrone, M.Garcia-Diaz, P.J.Tonge, C.Simmerling, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.07 / 2.30
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 126.095, 91.903, 102.846, 90.00, 106.45, 90.00
R / Rfree (%) 16.1 / 21.2

Sodium Binding Sites:

The binding sites of Sodium atom in the The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility (pdb code 5coq). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility, PDB code: 5coq:

Sodium binding site 1 out of 1 in 5coq

Go back to Sodium Binding Sites List in 5coq
Sodium binding site 1 out of 1 in the The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of The Effect of Valine to Alanine Mutation on Inha Enzyme Crystallization Pattern and Substrate Binding Loop Conformation and Flexibility within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na303

b:29.5
occ:1.00
 O C:ALA226 2.4 35.5 1.0
O C:HOH472 2.5 50.6 1.0
O C:ASP223 2.7 43.3 1.0
O C:HOH479 2.7 51.3 1.0
O C:GLN224 2.8 38.1 1.0
C C:GLN224 3.5 41.0 1.0
C C:ALA226 3.5 35.0 1.0
O C:HOH412 3.7 53.5 1.0
C C:ASP223 3.8 45.7 1.0
CA C:GLN224 3.8 46.5 1.0
N C:GLY229 4.2 35.3 1.0
N C:GLN224 4.2 46.9 1.0
N C:ALA226 4.3 39.4 1.0
CA C:GLY229 4.4 35.8 1.0
N C:PRO227 4.4 32.9 1.0
CA C:PRO227 4.4 32.6 1.0
CA C:ALA226 4.4 32.6 1.0
C C:PRO227 4.4 37.6 1.0
N C:ARG225 4.5 41.2 1.0
O C:PRO227 4.5 38.4 1.0
C C:ARG225 4.6 38.5 1.0
O C:HOH478 4.8 52.0 1.0
CB C:ALA226 4.9 34.5 1.0
N C:ILE228 5.0 33.4 1.0
O C:ARG225 5.0 37.5 1.0

Reference:

C.T.Lai, H.J.Li, W.Yu, S.Shah, G.R.Bommineni, V.Perrone, M.Garcia-Diaz, P.J.Tonge, C.Simmerling. Rational Modulation of the Induced-Fit Conformational Change For Slow-Onset Inhibition in Mycobacterium Tuberculosis Inha. Biochemistry V. 54 4683 2015.
ISSN: ISSN 0006-2960
PubMed: 26147157
DOI: 10.1021/ACS.BIOCHEM.5B00284
Page generated: Mon Oct 7 20:24:35 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy