Sodium in PDB 4rwy: Crystal Structure of VH1-46 Germline-Derived CD4-Binding Site-Directed Antibody 8ANC131 in Complex with Hiv-1 Clade B YU2 GP120

The structure of Crystal Structure of VH1-46 Germline-Derived CD4-Binding Site-Directed Antibody 8ANC131 in Complex with Hiv-1 Clade B YU2 GP120, PDB code: 4rwy was solved by P.Acharya, T.S.Luongo, P.D.Kwong, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.84 / 2.13
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	66.250, 67.137, 214.101, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 25.4

The binding sites of Sodium atom in the Crystal Structure of VH1-46 Germline-Derived CD4-Binding Site-Directed Antibody 8ANC131 in Complex with Hiv-1 Clade B YU2 GP120 (pdb code 4rwy). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of VH1-46 Germline-Derived CD4-Binding Site-Directed Antibody 8ANC131 in Complex with Hiv-1 Clade B YU2 GP120, PDB code: 4rwy:

Sodium binding site 1 out of 1 in the Crystal Structure of VH1-46 Germline-Derived CD4-Binding Site-Directed Antibody 8ANC131 in Complex with Hiv-1 Clade B YU2 GP120


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of VH1-46 Germline-Derived CD4-Binding Site-Directed Antibody 8ANC131 in Complex with Hiv-1 Clade B YU2 GP120 within 5.0Å range: probe atom residue distance (Å) B Occ H:Na305 b:60.7 occ:1.00 OD2 H:ASP208 3.9 57.4 1.0 O H:HOH443 4.2 50.5 1.0 HG H:SER156 4.3 82.3 1.0 OG H:SER156 4.6 68.6 1.0 CG H:ASP208 4.7 55.2 1.0 HD13 H:ILE195 4.9 62.8 1.0 HB3 H:ASP208 4.9 65.5 1.0 HD21 H:ASN197 5.0 66.7 1.0

T.Zhou, R.M.Lynch, L.Chen, P.Acharya, X.Wu, N.A.Doria-Rose, M.G.Joyce, D.Lingwood, C.Soto, R.T.Bailer, M.J.Ernandes, R.Kong, N.S.Longo, M.K.Louder, K.Mckee, S.O'dell, S.D.Schmidt, L.Tran, Z.Yang, A.Druz, T.S.Luongo, S.Moquin, S.Srivatsan, Y.Yang, B.Zhang, A.Zheng, M.Pancera, T.Kirys, I.S.Georgiev, T.Gindin, H.P.Peng, A.S.Yang, J.C.Mullikin, M.D.Gray, L.Stamatatos, D.R.Burton, W.C.Koff, M.S.Cohen, B.F.Haynes, J.P.Casazza, M.Connors, D.Corti, A.Lanzavecchia, Q.J.Sattentau, R.A.Weiss, A.P.West, P.J.Bjorkman, J.F.Scheid, M.C.Nussenzweig, L.Shapiro, J.R.Mascola, P.D.Kwong. Structural Repertoire of Hiv-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell(Cambridge,Mass.) V. 161 1280 2015.
ISSN: ISSN 0092-8674
PubMed: 26004070
DOI: 10.1016/J.CELL.2015.05.007