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Sodium in PDB 4rmj: Human SIRT2 in Complex with Adp Ribose and NicotinamideProtein crystallography data
The structure of Human SIRT2 in Complex with Adp Ribose and Nicotinamide, PDB code: 4rmj
was solved by
T.Rumpf,
M.Schiedel,
B.Karaman,
C.Roessler,
B.J.North,
A.Lehotzky,
J.Olah,
K.I.Ladwein,
K.Schmidtkunz,
M.Gajer,
M.Pannek,
C.Steegborn,
D.A.Sinclair,
S.Gerhardt,
J.Ovadi,
M.Schutkowski,
W.Sippl,
O.Einsle,
M.Jung,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4rmj:
The structure of Human SIRT2 in Complex with Adp Ribose and Nicotinamide also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Human SIRT2 in Complex with Adp Ribose and Nicotinamide
(pdb code 4rmj). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Human SIRT2 in Complex with Adp Ribose and Nicotinamide, PDB code: 4rmj: Sodium binding site 1 out of 1 in 4rmjGo back to Sodium Binding Sites List in 4rmj
Sodium binding site 1 out
of 1 in the Human SIRT2 in Complex with Adp Ribose and Nicotinamide
Mono view Stereo pair view
Reference:
T.Rumpf,
M.Schiedel,
B.Karaman,
C.Roessler,
B.J.North,
A.Lehotzky,
J.Olah,
K.I.Ladwein,
K.Schmidtkunz,
M.Gajer,
M.Pannek,
C.Steegborn,
D.A.Sinclair,
S.Gerhardt,
J.Ovadi,
M.Schutkowski,
W.Sippl,
O.Einsle,
M.Jung.
Selective SIRT2 Inhibition By Ligand-Induced Rearrangement of the Active Site. Nat Commun V. 6 6263 2015.
Page generated: Tue Dec 15 07:24:06 2020
ISSN: ESSN 2041-1723 PubMed: 25672491 DOI: 10.1038/NCOMMS7263 |
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