Sodium in PDB 4qc4: Crystal Structure of C117S Mutant of Human Acidic Fibroblast Growth Factor

The structure of Crystal Structure of C117S Mutant of Human Acidic Fibroblast Growth Factor, PDB code: 4qc4 was solved by M.Blaber, X.Xia, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.42 / 1.49
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	73.493, 95.223, 106.021, 90.00, 90.00, 90.00
R / Rfree (%)	16.2 / 18.2

The binding sites of Sodium atom in the Crystal Structure of C117S Mutant of Human Acidic Fibroblast Growth Factor (pdb code 4qc4). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of C117S Mutant of Human Acidic Fibroblast Growth Factor, PDB code: 4qc4:

Sodium binding site 1 out of 1 in the Crystal Structure of C117S Mutant of Human Acidic Fibroblast Growth Factor


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of C117S Mutant of Human Acidic Fibroblast Growth Factor within 5.0Å range: probe atom residue distance (Å) B Occ A:Na202 b:26.7 occ:1.00 O A:HOH495 2.4 33.7 1.0 OG A:SER76 2.7 12.9 1.0 O A:HOH353 2.8 24.9 1.0 O A:HOH323 2.9 16.2 1.0 ND2 A:ASN80 3.5 14.7 1.0 CB A:SER76 3.7 12.4 1.0 CA A:SER76 4.1 11.3 1.0 CE2 A:TYR74 4.1 11.8 1.0 OH A:TYR74 4.2 12.6 1.0 O A:HOH484 4.2 36.7 1.0 N A:GLN77 4.3 12.3 0.4 N A:GLN77 4.3 12.2 0.6 OG1 A:THR78 4.5 16.8 1.0 O A:THR78 4.5 12.8 1.0 C A:SER76 4.7 12.6 1.0 CZ A:TYR74 4.7 10.7 1.0 N A:THR78 4.8 11.3 1.0 CG A:ASN80 4.8 13.5 1.0

X.Xia, L.M.Longo, M.Blaber. Mutation Choice to Eliminate Buried Free Cysteines in Protein Therapeutics. J.Pharm.Sci. V. 104 566 2015.
ISSN: ISSN 0022-3549
PubMed: 25312595
DOI: 10.1002/JPS.24188