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Sodium in PDB 4ph5: Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position

Enzymatic activity of Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position

All present enzymatic activity of Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position:
2.7.7.7;

Protein crystallography data

The structure of Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position, PDB code: 4ph5 was solved by M.C.Koag, S.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.55
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 50.613, 80.377, 55.294, 90.00, 107.61, 90.00
R / Rfree (%) 19.1 / 26.1

Other elements in 4ph5:

The structure of Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position (pdb code 4ph5). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position, PDB code: 4ph5:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in 4ph5

Go back to Sodium Binding Sites List in 4ph5
Sodium binding site 1 out of 2 in the Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na403

b:36.7
occ:1.00
OP1 D:DC3 2.5 28.8 1.0
O A:LYS60 2.5 32.5 1.0
O A:VAL65 2.6 30.4 1.0
O A:HOH522 2.7 32.7 1.0
O A:LEU62 2.7 32.8 1.0
P D:DC3 3.6 28.5 1.0
C A:VAL65 3.6 30.2 1.0
C A:LYS60 3.6 29.4 1.0
C A:LEU62 3.7 33.1 1.0
OP2 D:DC3 3.8 30.6 1.0
N A:VAL65 3.9 27.2 1.0
N A:GLY64 4.2 29.9 1.0
O A:LYS61 4.2 31.8 1.0
CA A:VAL65 4.2 30.5 1.0
C A:LYS61 4.2 27.0 1.0
CA A:PRO63 4.4 30.9 1.0
CA A:LYS60 4.4 33.1 1.0
N A:LEU62 4.4 30.9 1.0
N A:PRO63 4.4 35.4 1.0
CG A:LYS60 4.5 28.5 1.0
N A:LYS61 4.6 28.1 1.0
N A:GLY66 4.6 28.1 1.0
CB A:VAL65 4.6 28.8 1.0
O3' D:DT2 4.6 33.5 1.0
CA A:LYS61 4.7 26.7 1.0
O5' D:DC3 4.7 37.3 1.0
C A:PRO63 4.7 32.4 1.0
CA A:LEU62 4.7 28.9 1.0
CA A:GLY66 4.8 28.0 1.0
C A:GLY64 4.8 30.1 1.0

Sodium binding site 2 out of 2 in 4ph5

Go back to Sodium Binding Sites List in 4ph5
Sodium binding site 2 out of 2 in the Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Structure of Human Dna Polymerase Beta Complexed with A Nicked Dna Containing A Ac at N-1 Position and Gc at N Position within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Na404

b:19.6
occ:1.00
OP1 P:DG9 2.3 26.3 1.0
O A:THR101 2.3 25.7 1.0
O P:HOH101 2.5 22.5 1.0
O A:ILE106 2.6 26.9 1.0
O A:VAL103 2.8 22.0 1.0
O A:HOH521 3.1 25.0 1.0
P P:DG9 3.3 21.5 1.0
C A:THR101 3.3 24.8 1.0
OP2 P:DG9 3.3 27.8 1.0
C A:ILE106 3.6 25.1 1.0
C A:VAL103 3.6 22.1 1.0
N A:ILE106 3.9 20.0 1.0
CA A:SER104 3.9 17.6 1.0
CA A:THR101 4.0 22.1 1.0
N A:GLY105 4.0 21.8 1.0
N A:SER104 4.1 20.2 1.0
CA A:ILE106 4.2 18.7 1.0
C A:ARG102 4.3 24.2 1.0
N A:ARG102 4.3 22.2 1.0
N A:VAL103 4.3 25.0 1.0
O5' P:DG9 4.4 28.5 1.0
O3' P:DC8 4.4 25.0 1.0
C A:SER104 4.4 20.8 1.0
N A:GLY107 4.5 23.9 1.0
O A:ARG102 4.6 26.6 1.0
CA A:ARG102 4.6 22.1 1.0
CB A:THR101 4.6 23.0 1.0
CA A:VAL103 4.6 24.9 1.0
CB A:ILE106 4.7 24.1 1.0
CA A:GLY107 4.8 23.3 1.0
C A:GLY105 4.8 22.3 1.0
O A:LEU100 5.0 22.0 1.0

Reference:

M.C.Koag, S.Lee. The Spontaneous Base Substitution Mechanisms of Human Dna Polymerase Beta To Be Published.
Page generated: Mon Oct 7 17:42:53 2024

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