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Atomistry » Sodium » PDB 4lh6-4lzw » 4lxz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 4lh6-4lzw » 4lxz » |
Sodium in PDB 4lxz: Structure of Human HDAC2 in Complex with Saha (Vorinostat)Enzymatic activity of Structure of Human HDAC2 in Complex with Saha (Vorinostat)
All present enzymatic activity of Structure of Human HDAC2 in Complex with Saha (Vorinostat):
3.5.1.98; Protein crystallography data
The structure of Structure of Human HDAC2 in Complex with Saha (Vorinostat), PDB code: 4lxz
was solved by
R.Fong,
P.J.Lupardus,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4lxz:
The structure of Structure of Human HDAC2 in Complex with Saha (Vorinostat) also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Structure of Human HDAC2 in Complex with Saha (Vorinostat)
(pdb code 4lxz). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the Structure of Human HDAC2 in Complex with Saha (Vorinostat), PDB code: 4lxz: Jump to Sodium binding site number: 1; 2; 3; Sodium binding site 1 out of 3 in 4lxzGo back to Sodium Binding Sites List in 4lxz
Sodium binding site 1 out
of 3 in the Structure of Human HDAC2 in Complex with Saha (Vorinostat)
Mono view Stereo pair view
Sodium binding site 2 out of 3 in 4lxzGo back to Sodium Binding Sites List in 4lxz
Sodium binding site 2 out
of 3 in the Structure of Human HDAC2 in Complex with Saha (Vorinostat)
Mono view Stereo pair view
Sodium binding site 3 out of 3 in 4lxzGo back to Sodium Binding Sites List in 4lxz
Sodium binding site 3 out
of 3 in the Structure of Human HDAC2 in Complex with Saha (Vorinostat)
Mono view Stereo pair view
Reference:
B.E.Lauffer,
R.Mintzer,
R.Fong,
S.Mukund,
C.Tam,
I.Zilberleyb,
B.Flicke,
A.Ritscher,
G.Fedorowicz,
R.Vallero,
D.F.Ortwine,
J.Gunzner,
Z.Modrusan,
L.Neumann,
C.M.Koth,
P.J.Lupardus,
J.S.Kaminker,
C.E.Heise,
P.Steiner.
Histone Deacetylase (Hdac) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation But Not Transcription and Cell Viability. J.Biol.Chem. V. 288 26926 2013.
Page generated: Tue Dec 15 06:52:52 2020
ISSN: ISSN 0021-9258 PubMed: 23897821 DOI: 10.1074/JBC.M113.490706 |
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