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Atomistry » Sodium » PDB 4lh6-4lzw » 4lxb | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Sodium » PDB 4lh6-4lzw » 4lxb » |
Sodium in PDB 4lxb: Crystal Structure Analysis of Thrombin in Complex with Compound D58Enzymatic activity of Crystal Structure Analysis of Thrombin in Complex with Compound D58
All present enzymatic activity of Crystal Structure Analysis of Thrombin in Complex with Compound D58:
3.4.21.5; Protein crystallography data
The structure of Crystal Structure Analysis of Thrombin in Complex with Compound D58, PDB code: 4lxb
was solved by
C.Stehlin-Gaon,
Z.Bocskei,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4lxb:
The structure of Crystal Structure Analysis of Thrombin in Complex with Compound D58 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Crystal Structure Analysis of Thrombin in Complex with Compound D58
(pdb code 4lxb). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure Analysis of Thrombin in Complex with Compound D58, PDB code: 4lxb: Jump to Sodium binding site number: 1; 2; Sodium binding site 1 out of 2 in 4lxbGo back to Sodium Binding Sites List in 4lxb
Sodium binding site 1 out
of 2 in the Crystal Structure Analysis of Thrombin in Complex with Compound D58
Mono view Stereo pair view
Sodium binding site 2 out of 2 in 4lxbGo back to Sodium Binding Sites List in 4lxb
Sodium binding site 2 out
of 2 in the Crystal Structure Analysis of Thrombin in Complex with Compound D58
Mono view Stereo pair view
Reference:
J.Meneyrol,
M.Follmann,
G.Lassalle,
V.Wehner,
G.Barre,
T.Rousseaux,
J.M.Altenburger,
F.Petit,
Z.Bocskei,
H.Schreuder,
N.Alet,
J.P.Herault,
L.Millet,
F.Dol,
P.Florian,
P.Schaeffer,
F.Sadoun,
S.Klieber,
C.Briot,
F.Bono,
J.M.Herbert.
5-Chlorothiophene-2-Carboxylic Acid [(S)-2-[2-Methyl-3-(2-Oxopyrrolidin-1-Yl) Benzenesulfonylamino]-3-(4-Methylpiperazin-1-Yl)-3- Oxopropyl]Amide (SAR107375), A Selective and Potent Orally Active Dual Thrombin and Factor Xa Inhibitor. J.Med.Chem. V. 56 9441 2013.
Page generated: Tue Dec 15 06:52:49 2020
ISSN: ISSN 0022-2623 PubMed: 24175584 DOI: 10.1021/JM4005835 |
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