Sodium in PDB 4kgh: Crystal Structure of Human SPLUNC1 Lacking the Secretion Signal Sequence

The structure of Crystal Structure of Human SPLUNC1 Lacking the Secretion Signal Sequence, PDB code: 4kgh was solved by L.Betts, W.G.Walton, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.64 / 2.81
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	47.475, 203.727, 118.612, 90.00, 90.00, 90.00
R / Rfree (%)	24.6 / 29.5

The binding sites of Sodium atom in the Crystal Structure of Human SPLUNC1 Lacking the Secretion Signal Sequence (pdb code 4kgh). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human SPLUNC1 Lacking the Secretion Signal Sequence, PDB code: 4kgh:

Sodium binding site 1 out of 1 in the Crystal Structure of Human SPLUNC1 Lacking the Secretion Signal Sequence


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human SPLUNC1 Lacking the Secretion Signal Sequence within 5.0Å range: probe atom residue distance (Å) B Occ B:Na303 b:56.7 occ:1.00 O B:SER149 3.6 83.3 1.0 N B:GLY194 3.6 60.5 1.0 CA B:GLY194 3.7 62.8 1.0 C B:ASP193 3.7 63.0 1.0 CB B:ASP193 3.8 63.0 1.0 CG B:ASP193 3.8 69.1 1.0 O B:ASP193 3.9 64.2 1.0 OG B:SER149 3.9 95.1 1.0 CB B:SER149 4.0 87.5 1.0 C B:GLY194 4.0 65.4 1.0 C B:SER149 4.0 78.3 1.0 NE2 B:GLN140 4.1 69.8 1.0 N B:LEU195 4.1 63.0 1.0 OD2 B:ASP193 4.1 73.3 1.0 C B:LEU150 4.2 62.1 1.0 OD1 B:ASP193 4.2 68.2 1.0 O B:LEU150 4.2 61.3 1.0 N B:ARG152 4.2 62.2 1.0 C B:LEU151 4.3 60.4 1.0 N B:LEU151 4.3 60.9 1.0 CB B:ARG152 4.3 63.9 1.0 CA B:ASP193 4.4 61.7 1.0 CA B:LEU151 4.5 61.9 1.0 N B:LEU150 4.5 71.3 1.0 O B:LEU151 4.6 59.3 1.0 CA B:SER149 4.7 81.1 1.0 O B:GLY194 4.7 69.3 1.0 CG B:ARG152 4.7 70.9 1.0 CA B:LEU150 4.8 68.8 1.0 CA B:ARG152 4.9 59.3 1.0 CA B:LEU195 5.0 71.8 1.0

A.L.Garland, W.G.Walton, R.D.Coakley, C.D.Tan, R.C.Gilmore, C.A.Hobbs, A.Tripathy, L.A.Clunes, S.Bencharit, M.J.Stutts, L.Betts, M.R.Redinbo, R.Tarran. Molecular Basis For pH-Dependent Mucosal Dehydration in Cystic Fibrosis Airways. Proc.Natl.Acad.Sci.Usa V. 110 15973 2013.
ISSN: ISSN 0027-8424
PubMed: 24043776
DOI: 10.1073/PNAS.1311999110