Sodium in PDB 4iz7: Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain

All present enzymatic activity of Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain:
2.7.11.24;

The structure of Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain, PDB code: 4iz7 was solved by P.D.Mace, H.Robinson, S.J.Riedl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.70 / 1.80
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	73.478, 205.334, 57.746, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 22.2

The binding sites of Sodium atom in the Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain (pdb code 4iz7). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain, PDB code: 4iz7:

Sodium binding site 1 out of 1 in the Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structure of Non-Phosphorylated ERK2 Bound to the Pea-15 Death Effector Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Na401 b:27.2 occ:1.00 O A:HOH737 2.1 40.9 1.0 O A:ALA282 2.2 21.5 1.0 O A:PRO280 2.4 21.3 1.0 C A:ALA282 3.3 22.3 1.0 C A:PRO280 3.4 21.2 1.0 C A:ASN281 3.6 23.0 1.0 N A:ALA282 3.7 22.1 1.0 O A:ASN281 3.7 21.6 1.0 ND2 A:ASN276 3.9 34.0 1.0 O A:HOH738 4.0 51.4 1.0 CA A:ASN281 4.1 22.4 1.0 CA A:ALA282 4.1 22.8 1.0 N A:ASN281 4.2 20.9 1.0 N A:ASP283 4.3 22.1 1.0 CA A:PRO280 4.4 20.6 1.0 N A:SER284 4.4 21.4 1.0 C A:ASP283 4.6 22.6 1.0 CA A:ASP283 4.6 22.1 1.0 O A:PHE279 4.8 22.9 1.0 CD1 A:LEU287 5.0 23.6 1.0

P.D.Mace, Y.Wallez, M.F.Egger, M.K.Dobaczewska, H.Robinson, E.B.Pasquale, S.J.Riedl. Structure of ERK2 Bound to Pea-15 Reveals A Mechanism For Rapid Release of Activated Mapk. Nat Commun V. 4 1681 2013.
ISSN: ESSN 2041-1723
PubMed: 23575685
DOI: 10.1038/NCOMMS2687