Sodium in PDB 4imk: Uncrossed Fab Binding to Human Angiopoietin 2

The structure of Uncrossed Fab Binding to Human Angiopoietin 2, PDB code: 4imk was solved by S.Fenn, C.Schiller, J.J.Griese, K.-P.Hopfner, H.Kettenberger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.76 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	65.969, 86.670, 205.813, 90.00, 90.00, 90.00
R / Rfree (%)	19.9 / 22.6

The binding sites of Sodium atom in the Uncrossed Fab Binding to Human Angiopoietin 2 (pdb code 4imk). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Uncrossed Fab Binding to Human Angiopoietin 2, PDB code: 4imk:

Sodium binding site 1 out of 1 in the Uncrossed Fab Binding to Human Angiopoietin 2


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Uncrossed Fab Binding to Human Angiopoietin 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na301 b:64.2 occ:1.00 OG A:SER7 2.6 48.0 1.0 O A:GLY8 2.6 40.9 1.0 OE2 A:GLU10 2.8 60.0 1.0 CB A:SER7 3.2 47.9 1.0 CG A:GLU10 3.3 51.0 1.0 CD A:GLU10 3.4 57.6 1.0 CG2 A:THR123 3.7 41.8 1.0 C A:SER7 3.7 50.3 1.0 C A:GLY8 3.8 42.4 1.0 N A:GLY8 3.8 47.2 1.0 CA A:SER7 4.0 49.0 1.0 O A:LYS19 4.1 43.9 1.0 O A:SER7 4.1 53.2 1.0 CA A:VAL20 4.2 40.2 1.0 CG2 A:VAL20 4.2 40.8 1.0 CG1 A:VAL20 4.3 38.5 1.0 CA A:GLY8 4.4 41.4 1.0 CB A:VAL20 4.4 40.2 1.0 OE1 A:GLU10 4.7 60.0 1.0 CB A:GLU10 4.7 45.5 1.0 N A:SER7 4.7 50.3 1.0 OG1 A:THR123 4.8 46.1 1.0 CB A:THR123 4.8 43.1 1.0 C A:LYS19 4.8 44.3 1.0 N A:SER21 4.9 38.5 1.0 N A:ALA9 4.9 41.1 1.0 N A:VAL20 4.9 46.4 1.0 C A:ALA9 5.0 46.1 1.0

S.Fenn, C.B.Schiller, J.J.Griese, H.Duerr, S.Imhof-Jung, C.Gassner, J.Moelleken, J.T.Regula, W.Schaefer, M.Thomas, C.Klein, K.P.Hopfner, H.Kettenberger. Crystal Structure of An Anti-ANG2 Crossfab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One V. 8 61953 2013.
ISSN: ESSN 1932-6203
PubMed: 23613981
DOI: 10.1371/JOURNAL.PONE.0061953