Sodium in PDB 4gwn: Crystal Structure of Human Mature Meprin Beta

All present enzymatic activity of Crystal Structure of Human Mature Meprin Beta:
3.4.24.63;

The structure of Crystal Structure of Human Mature Meprin Beta, PDB code: 4gwn was solved by J.L.Arolas, C.Broder, T.Jefferson, T.Guevara, E.E.Sterchi, W.Bode, W.Stocker, C.Becker-Pauly, F.X.Gomis-Ruth, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.16 / 3.00
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	74.960, 74.960, 502.650, 90.00, 90.00, 120.00
R / Rfree (%)	19.6 / 23.8

The structure of Crystal Structure of Human Mature Meprin Beta also contains other interesting chemical elements:

Cadmium

(Cd)

1 atom

The binding sites of Sodium atom in the Crystal Structure of Human Mature Meprin Beta (pdb code 4gwn). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of Human Mature Meprin Beta, PDB code: 4gwn:

Sodium binding site 1 out of 1 in the Crystal Structure of Human Mature Meprin Beta


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Mature Meprin Beta within 5.0Å range: probe atom residue distance (Å) B Occ A:Na702 b:99.8 occ:1.00 O A:PHE310 2.2 0.8 1.0 OG A:SER300 2.2 0.8 1.0 O A:SER266 2.3 0.6 1.0 OD1 A:ASP298 2.5 0.0 1.0 OD2 A:ASP418 2.5 0.3 1.0 OD1 A:ASP418 2.7 0.9 1.0 OE2 A:GLU268 2.9 99.6 1.0 CG A:ASP418 2.9 0.9 1.0 CB A:SER300 3.1 0.2 1.0 C A:SER266 3.4 0.4 1.0 C A:PHE310 3.4 0.1 1.0 CG A:ASP298 3.5 0.9 1.0 N A:PHE310 3.9 0.2 1.0 CD A:GLU268 3.9 0.5 1.0 CB A:ASP298 3.9 0.1 1.0 CA A:SER266 4.0 0.9 1.0 CB A:SER266 4.0 0.2 1.0 N A:SER300 4.1 0.5 1.0 CA A:SER300 4.2 0.9 1.0 CA A:PHE310 4.2 0.8 1.0 OD1 A:ASP419 4.3 89.3 1.0 CB A:ASP418 4.5 93.9 1.0 N A:PHE311 4.5 0.4 1.0 N A:PHE267 4.5 0.9 1.0 OE1 A:GLU268 4.6 0.4 1.0 OD2 A:ASP298 4.6 0.2 1.0 CG A:GLU268 4.8 0.9 1.0 CA A:PHE311 4.8 97.8 1.0 C A:GLY309 4.8 0.4 1.0 CB A:PHE267 4.9 0.3 1.0 N A:HIS299 4.9 96.6 1.0 C A:PHE267 4.9 0.1 1.0 OG A:SER266 5.0 0.5 1.0 CA A:PHE267 5.0 0.2 1.0

J.L.Arolas, C.Broder, T.Jefferson, T.Guevara, E.E.Sterchi, W.Bode, W.Stocker, C.Becker-Pauly, F.X.Gomis-Ruth. Structural Basis For the Sheddase Function of Human Meprin Beta Metalloproteinase at the Plasma Membrane Proc.Natl.Acad.Sci.Usa V. 109 16131 2012.
ISSN: ISSN 0027-8424
PubMed: 22988105
DOI: 10.1073/PNAS.1211076109