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Sodium in PDB 4g8j: X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution

Enzymatic activity of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution

All present enzymatic activity of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution:
2.4.2.3;

Protein crystallography data

The structure of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution, PDB code: 4g8j was solved by A.A.Lashkov, A.G.Gabdoulkhakov, I.I.Prokofev, S.E.Sotnichenko, C.Betzel, A.M.Mikhailov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 11.99 / 2.12
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 91.796, 95.905, 91.890, 90.00, 119.96, 90.00
R / Rfree (%) 14.9 / 19.7

Other elements in 4g8j:

The structure of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Chlorine (Cl) 9 atoms

Sodium Binding Sites:

The binding sites of Sodium atom in the X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution (pdb code 4g8j). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 3 binding sites of Sodium where determined in the X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution, PDB code: 4g8j:
Jump to Sodium binding site number: 1; 2; 3;

Sodium binding site 1 out of 3 in 4g8j

Go back to Sodium Binding Sites List in 4g8j
Sodium binding site 1 out of 3 in the X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Na303

b:18.9
occ:1.00
OE2 A:GLU48 2.5 15.5 1.0
OE2 B:GLU48 2.6 15.4 1.0
OG A:SER72 2.6 10.6 1.0
O B:ILE68 2.8 13.2 1.0
O A:ILE68 3.0 12.7 1.0
CB A:SER72 3.1 11.8 1.0
OG B:SER72 3.1 10.7 1.0
O A:HOH501 3.4 17.4 1.0
N B:ILE68 3.4 11.6 1.0
CB B:SER72 3.4 8.8 1.0
N A:ILE68 3.6 11.2 1.0
CD A:GLU48 3.6 18.4 1.0
CD B:GLU48 3.7 16.5 1.0
C B:ILE68 3.8 12.1 1.0
C A:ILE68 3.9 10.2 1.0
CA B:ILE68 4.1 12.8 1.0
C A:GLY67 4.1 15.0 1.0
CG A:GLU48 4.1 13.1 1.0
CA A:GLY67 4.1 14.7 1.0
C B:GLY67 4.1 13.6 1.0
CA B:GLY67 4.2 12.7 1.0
CA A:ILE68 4.3 13.1 1.0
CG B:GLU48 4.3 12.2 1.0
CA A:SER72 4.5 11.2 1.0
CB B:ILE68 4.5 12.4 1.0
O A:THR66 4.6 15.6 1.0
OE1 A:GLU48 4.6 19.1 1.0
OE1 B:GLU48 4.7 16.2 1.0
N A:SER72 4.8 10.2 1.0
CB A:ILE68 4.8 14.7 1.0
O B:THR66 4.8 11.4 1.0
CB A:GLU48 4.8 14.7 1.0
CA B:SER72 4.8 12.3 1.0
N B:GLY69 5.0 10.7 1.0
O A:GLY67 5.0 15.1 1.0

Sodium binding site 2 out of 3 in 4g8j

Go back to Sodium Binding Sites List in 4g8j
Sodium binding site 2 out of 3 in the X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Na306

b:16.1
occ:1.00
OE2 C:GLU48 2.6 17.8 1.0
OE2 D:GLU48 2.6 14.1 1.0
OG D:SER72 2.6 10.1 1.0
OG C:SER72 2.6 11.3 1.0
O C:ILE68 2.8 10.8 1.0
O D:ILE68 2.9 11.5 1.0
CB D:SER72 3.2 9.2 1.0
CB C:SER72 3.2 9.0 1.0
O C:HOH531 3.3 15.3 1.0
N C:ILE68 3.5 11.7 1.0
CD C:GLU48 3.6 14.8 1.0
N D:ILE68 3.6 11.9 1.0
C C:ILE68 3.7 12.4 1.0
CD D:GLU48 3.7 15.5 1.0
C D:ILE68 3.9 12.9 1.0
CG C:GLU48 3.9 24.0 1.0
CA C:ILE68 4.1 15.6 1.0
C C:GLY67 4.1 14.0 1.0
CA D:ILE68 4.3 13.2 1.0
CA C:GLY67 4.3 13.1 1.0
C D:GLY67 4.3 13.5 1.0
CA D:GLY67 4.4 12.2 1.0
CG D:GLU48 4.4 11.4 1.0
CA D:SER72 4.5 8.0 1.0
CA C:SER72 4.6 9.6 1.0
CB C:ILE68 4.6 14.7 1.0
OE1 D:GLU48 4.7 15.3 1.0
OE1 C:GLU48 4.7 16.5 1.0
N D:SER72 4.7 6.0 1.0
N C:SER72 4.8 9.5 1.0
O C:THR66 4.8 12.5 1.0
O D:THR66 4.8 9.6 1.0
CB D:ILE68 4.8 15.7 1.0
N C:GLY69 4.9 11.1 1.0
CB C:GLU48 5.0 11.8 1.0

Sodium binding site 3 out of 3 in 4g8j

Go back to Sodium Binding Sites List in 4g8j
Sodium binding site 3 out of 3 in the X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine at 2.12 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Na304

b:18.2
occ:1.00
OE2 E:GLU48 2.6 15.3 1.0
OG E:SER72 2.6 12.3 1.0
OG F:SER72 2.7 11.9 1.0
O F:ILE68 2.7 11.6 1.0
O E:ILE68 2.8 14.3 1.0
CB E:SER72 3.1 10.5 1.0
OE2 F:GLU48 3.1 18.1 1.0
O F:HOH487 3.2 17.3 1.0
CB F:SER72 3.3 14.6 1.0
N F:ILE68 3.5 14.2 1.0
N E:ILE68 3.6 12.0 1.0
C F:ILE68 3.7 11.9 1.0
CD E:GLU48 3.7 17.9 1.0
C E:ILE68 3.8 11.4 1.0
CD F:GLU48 4.1 20.0 1.0
CA F:ILE68 4.1 11.7 1.0
C F:GLY67 4.2 14.8 1.0
CA E:ILE68 4.2 12.5 1.0
C E:GLY67 4.2 13.6 1.0
CG E:GLU48 4.3 12.5 1.0
CA E:GLY67 4.3 15.2 1.0
CA F:GLY67 4.3 16.6 1.0
CA E:SER72 4.5 9.6 1.0
CG F:GLU48 4.5 14.4 1.0
CB F:ILE68 4.6 12.0 1.0
CA F:SER72 4.6 11.8 1.0
N E:SER72 4.7 9.2 1.0
O E:THR66 4.7 13.6 1.0
CB E:ILE68 4.7 14.7 1.0
O F:THR66 4.7 15.8 1.0
OE1 E:GLU48 4.8 17.7 1.0
N F:SER72 4.8 10.4 1.0
N F:GLY69 4.9 12.2 1.0
N E:GLY69 4.9 12.0 1.0

Reference:

A.A.Lashkov, A.G.Gabdoulkhakov, I.I.Prokofev, S.E.Sotnichenko, C.Betzel, A.M.Mikhailov. X-Ray Structure of Uridine Phosphorylease From Vibrio Cholerae Complexed with Thymidine To Be Published.
Page generated: Mon Oct 7 15:31:48 2024

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