Sodium in PDB 4e41: Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4

All present enzymatic activity of Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4:
5.3.1.1;

The structure of Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4, PDB code: 4e41 was solved by L.Deng, R.J.Langley, Q.Wang, S.L.Topalian, R.A.Mariuzza, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	126.133, 175.611, 88.646, 90.00, 110.75, 90.00
R / Rfree (%)	19.7 / 26.4

The binding sites of Sodium atom in the Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4 (pdb code 4e41). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4, PDB code: 4e41:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4 within 5.0Å range: probe atom residue distance (Å) B Occ A:Na201 b:72.1 occ:1.00 O G:THR185 2.4 68.3 1.0 OG1 G:THR185 2.9 68.1 1.0 OE1 G:GLU187 2.9 69.6 1.0 OE2 A:GLU98 3.0 63.8 1.0 OE1 A:GLU98 3.1 62.2 1.0 CD A:GLU98 3.4 62.0 1.0 OE1 A:GLU101 3.4 63.0 1.0 C G:THR185 3.5 68.2 1.0 CD G:GLU187 3.8 71.1 1.0 OE2 A:GLU101 3.9 63.7 1.0 OE2 G:GLU187 3.9 72.3 1.0 CB G:THR185 3.9 68.3 1.0 CD A:GLU101 4.0 62.7 1.0 CA G:THR185 4.2 68.3 1.0 N G:THR185 4.3 68.9 1.0 N G:VAL186 4.6 68.2 1.0 CG A:GLU98 4.7 60.2 1.0 CA G:VAL186 4.8 68.4 1.0

Sodium binding site 2 out of 2 in the Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Structural Basis For the Recognition of Mutant Self By A Tumor- Specific, Mhc Class II-Restricted T Cell Receptor G4 within 5.0Å range: probe atom residue distance (Å) B Occ B:Na201 b:53.8 occ:1.00 O B:THR185 2.3 62.8 1.0 OE1 F:GLU98 2.5 68.0 1.0 CD F:GLU98 3.2 66.8 1.0 OG1 B:THR185 3.2 63.3 1.0 OE2 F:GLU98 3.2 66.9 1.0 C B:THR185 3.4 62.9 1.0 OE2 F:GLU101 3.5 61.9 1.0 N B:THR185 4.0 62.8 1.0 CA B:THR185 4.1 62.9 1.0 CB B:THR185 4.1 62.8 1.0 CG F:GLU98 4.5 64.6 1.0 N B:VAL186 4.5 63.0 1.0 CD F:GLU101 4.6 62.4 1.0 CA B:VAL186 4.8 63.6 1.0

L.Deng, R.J.Langley, Q.Wang, S.L.Topalian, R.A.Mariuzza. Structural Basis For the Recognition of Mutant Self By A Tumor-Specific, Mhc Class II-Restricted T Cell Receptor G4 Proc.Natl.Acad.Sci.Usa 2012.
ISSN: ESSN 1091-6490