Sodium in PDB 4bqc: Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos

The structure of Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos, PDB code: 4bqc was solved by C.H.Bell, E.Healey, S.Vanerp, B.Bishop, C.Tang, R.J.C.Gilbert, A.R.Aricescu, R.J.Pasterkamp, C.Siebold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 3.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	96.160, 157.840, 89.920, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 25.9

The binding sites of Sodium atom in the Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos (pdb code 4bqc). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos, PDB code: 4bqc:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos within 5.0Å range: probe atom residue distance (Å) B Occ A:Na2086 b:51.7 occ:1.00 O A:LYS1017 2.5 54.0 1.0 OE1 A:GLU982 2.9 51.0 1.0 N A:SER1068 3.1 54.8 1.0 CG2 A:THR1019 3.5 59.7 1.0 C A:LYS1017 3.5 54.6 1.0 CB A:SER1068 3.5 60.7 1.0 OE2 A:GLU982 3.6 70.0 1.0 CB A:LYS1017 3.6 56.4 1.0 CD A:GLU982 3.6 71.6 1.0 CB A:ASN1067 3.7 50.4 1.0 N A:LYS1017 3.7 48.4 1.0 CA A:LYS1017 3.8 50.5 1.0 CA A:ASN1067 3.9 49.6 1.0 CA A:SER1068 3.9 55.9 1.0 OG A:SER1068 4.0 67.6 1.0 C A:ASN1067 4.0 55.0 1.0 C A:GLY1016 4.7 52.1 1.0 N A:ILE1018 4.7 52.4 1.0 CG A:ASN1067 4.7 68.6 1.0 CB A:THR1019 4.8 60.3 1.0 N A:THR1019 4.9 53.7 1.0 CG A:LYS1017 5.0 68.6 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the FN5 and FN6 Domains of NEO1 Bound to Sos within 5.0Å range: probe atom residue distance (Å) B Occ B:Na2084 b:71.8 occ:1.00 O B:LYS1017 2.7 70.4 1.0 OE1 B:GLU982 2.8 64.8 1.0 N B:SER1068 3.1 57.6 1.0 CB B:SER1068 3.4 66.4 1.0 OE2 B:GLU982 3.5 85.9 1.0 CG2 B:THR1019 3.5 77.1 1.0 CD B:GLU982 3.5 87.6 1.0 C B:LYS1017 3.7 70.1 1.0 CB B:LYS1017 3.8 68.8 1.0 CA B:SER1068 3.8 60.0 1.0 N B:LYS1017 3.8 63.7 1.0 CB B:ASN1067 3.8 55.8 1.0 OG B:SER1068 3.8 80.4 1.0 CA B:LYS1017 3.9 65.0 1.0 CA B:ASN1067 4.0 55.8 1.0 C B:ASN1067 4.0 58.8 1.0 C B:GLY1016 4.8 66.2 1.0 CG B:ASN1067 4.8 71.2 1.0 CB B:THR1019 4.9 77.6 1.0 N B:ILE1018 4.9 66.6 1.0

C.H.Bell, E.Healey, S.Van Erp, B.Bishop, C.Tang, R.J.C.Gilbert, A.R.Aricescu, R.J.Pasterkamp, C.Siebold. Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub Science V. 341 77 2013.
ISSN: ISSN 0036-8075
PubMed: 23744777
DOI: 10.1126/SCIENCE.1232322