Sodium in PDB 4b5p: Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant

All present enzymatic activity of Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant:
2.3.1.108;

The structure of Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant, PDB code: 4b5p was solved by M.Taschner, M.Vetter, E.Lorentzen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.669 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.760, 110.870, 113.580, 90.00, 90.00, 90.00
R / Rfree (%)	18.49 / 22.16

The binding sites of Sodium atom in the Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant (pdb code 4b5p). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant, PDB code: 4b5p:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant within 5.0Å range: probe atom residue distance (Å) B Occ A:Na401 b:20.2 occ:1.00 HE22 A:GLN131 2.4 22.5 1.0 HZ3 A:LYS162 2.7 22.2 1.0 HG3 A:GLU128 2.9 25.6 1.0 HZ2 B:LYS162 2.9 24.8 1.0 NA B:NA401 2.9 20.8 1.0 HB2 A:ALA57 2.9 21.8 1.0 H71 A:ACO1197 3.0 23.4 1.0 O A:HOH2059 3.2 20.7 1.0 NE2 A:GLN131 3.2 18.8 1.0 HA A:ALA57 3.3 23.4 1.0 NZ A:LYS162 3.3 18.5 1.0 OE2 A:GLU128 3.3 23.1 1.0 HZ1 A:LYS162 3.4 22.2 1.0 HZ2 A:LYS162 3.4 22.2 1.0 HZ3 B:LYS162 3.4 24.8 1.0 H72 A:ACO1197 3.5 23.4 1.0 CG A:GLU128 3.5 21.4 1.0 NZ B:LYS162 3.6 20.7 1.0 HG2 A:GLU128 3.6 25.6 1.0 CB A:ALA57 3.6 18.1 1.0 C7P A:ACO1197 3.7 19.5 1.0 O A:ALA57 3.7 23.0 1.0 HE21 A:GLN131 3.8 22.5 1.0 CD A:GLU128 3.8 25.9 1.0 O A:HOH2057 3.8 19.8 1.0 HB3 A:ALA57 3.8 21.8 1.0 CA A:ALA57 3.8 19.5 1.0 OE1 A:GLN131 3.9 21.8 1.0 HZ1 B:LYS162 4.0 24.8 1.0 CD A:GLN131 4.0 17.2 1.0 HG3 B:GLU128 4.1 27.4 1.0 HG2 B:GLU128 4.1 27.4 1.0 C A:ALA57 4.2 20.6 1.0 HE1 A:TYR125 4.4 25.0 1.0 HB1 A:ALA57 4.5 21.8 1.0 N8P A:ACO1197 4.5 19.3 1.0 H62 A:ACO1197 4.5 22.5 1.0 CG B:GLU128 4.5 22.8 1.0 HA A:GLU128 4.6 24.0 1.0 HE3 B:LYS162 4.6 21.4 1.0 HD2 A:LYS162 4.7 23.8 1.0 CE A:LYS162 4.7 19.8 1.0 CE B:LYS162 4.7 17.8 1.0 C6P A:ACO1197 4.7 18.8 1.0 HE22 B:GLN131 4.8 22.3 1.0 HN8 A:ACO1197 4.8 23.2 1.0 O B:ALA57 4.9 21.8 1.0 CB A:GLU128 4.9 22.3 1.0 OE1 A:GLU128 4.9 21.8 1.0 HA B:ALA57 4.9 22.6 1.0 HE3 A:LYS162 4.9 23.8 1.0 OE2 B:GLU128 4.9 24.5 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of Human Alpha Tubulin Acetyltransferase Catalytic Domain Q58A Variant within 5.0Å range: probe atom residue distance (Å) B Occ B:Na401 b:20.8 occ:1.00 HE22 B:GLN131 2.4 22.3 1.0 HZ3 B:LYS162 2.7 24.8 1.0 H71 B:ACO1197 2.9 21.7 1.0 NA A:NA401 2.9 20.2 1.0 HB2 B:ALA57 2.9 25.9 1.0 HG3 B:GLU128 2.9 27.4 1.0 HZ2 A:LYS162 2.9 22.2 1.0 O A:HOH2057 3.1 19.8 1.0 NE2 B:GLN131 3.2 18.6 1.0 NZ B:LYS162 3.3 20.7 1.0 HA B:ALA57 3.4 22.6 1.0 OE2 B:GLU128 3.4 24.5 1.0 HZ2 B:LYS162 3.4 24.8 1.0 HZ1 B:LYS162 3.4 24.8 1.0 HZ3 A:LYS162 3.4 22.2 1.0 H72 B:ACO1197 3.5 21.7 1.0 NZ A:LYS162 3.6 18.5 1.0 C7P B:ACO1197 3.6 18.1 1.0 CB B:ALA57 3.7 21.6 1.0 CG B:GLU128 3.7 22.8 1.0 O B:ALA57 3.7 21.8 1.0 HE21 B:GLN131 3.8 22.3 1.0 O A:HOH2059 3.8 20.7 1.0 HG2 B:GLU128 3.8 27.4 1.0 HB3 B:ALA57 3.8 25.9 1.0 CD B:GLU128 3.9 23.2 1.0 OE1 B:GLN131 3.9 19.2 1.0 CA B:ALA57 3.9 18.9 1.0 HG2 A:GLU128 4.0 25.6 1.0 CD B:GLN131 4.0 19.3 1.0 HZ1 A:LYS162 4.0 22.2 1.0 HG3 A:GLU128 4.1 25.6 1.0 C B:ALA57 4.2 19.4 1.0 HE1 B:TYR125 4.3 25.6 0.1 HE1 B:TYR125 4.4 24.6 0.9 HB1 B:ALA57 4.5 25.9 1.0 N8P B:ACO1197 4.5 18.5 1.0 CG A:GLU128 4.5 21.4 1.0 H62 B:ACO1197 4.5 24.5 1.0 HE3 A:LYS162 4.6 23.8 1.0 HA B:GLU128 4.7 23.6 1.0 CE B:LYS162 4.7 17.8 1.0 HD2 B:LYS162 4.7 20.1 1.0 C6P B:ACO1197 4.7 20.4 1.0 CE A:LYS162 4.7 19.8 1.0 HE22 A:GLN131 4.8 22.5 1.0 HN8 B:ACO1197 4.8 22.2 1.0 HA A:ALA57 4.8 23.4 1.0 O A:ALA57 4.8 23.0 1.0 HE3 B:LYS162 4.9 21.4 1.0 OE2 A:GLU128 4.9 23.1 1.0 OE1 B:GLU128 5.0 22.3 1.0 CB B:GLU128 5.0 21.9 1.0

M.Taschner, M.Vetter, E.Lorentzen. Atomic Resolution Structure of Human Alpha-Tubulin Acetyltransferase Bound to Acetyl-Coa. Proc.Natl.Acad.Sci.Usa V. 109 19649 2012.
ISSN: ISSN 0027-8424
PubMed: 23071318
DOI: 10.1073/PNAS.1209343109