Sodium in PDB 3tav: Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus

All present enzymatic activity of Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus:
3.4.11.18;

The structure of Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus, PDB code: 3tav was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.15
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	119.640, 119.640, 96.190, 90.00, 90.00, 120.00
R / Rfree (%)	18.7 / 21.6

The structure of Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus also contains other interesting chemical elements:

Magnesium	(Mg)	4 atoms
Chlorine	(Cl)	3 atoms

The binding sites of Sodium atom in the Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus (pdb code 3tav). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 2 binding sites of Sodium where determined in the Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus, PDB code: 3tav:
Jump to Sodium binding site number: 1; 2;

Sodium binding site 1 out of 2 in the Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus within 5.0Å range: probe atom residue distance (Å) B Occ A:Na267 b:48.5 occ:1.00 O A:HOH281 2.3 48.2 1.0 O A:ALA244 2.3 46.4 1.0 O A:GLN83 2.4 46.3 1.0 O A:HOH278 2.4 42.3 1.0 O A:ASN81 2.6 50.9 1.0 C A:ALA244 3.2 45.5 1.0 C A:GLN83 3.6 49.1 1.0 C A:ASN81 3.6 50.8 1.0 N A:ALA244 3.7 50.8 1.0 OG A:SER102 3.8 44.1 1.0 CA A:ALA244 3.8 47.5 1.0 N A:ASN81 3.9 50.4 1.0 CB A:ALA244 3.9 46.4 1.0 CA A:ASN81 4.1 50.8 1.0 O A:SER79 4.2 46.2 1.0 N A:ALA245 4.2 43.3 1.0 C A:VAL80 4.3 49.4 1.0 N A:GLN83 4.3 50.7 1.0 CA A:VAL84 4.4 45.0 1.0 N A:VAL84 4.4 47.3 1.0 CA A:GLN83 4.5 50.6 1.0 O A:VAL84 4.5 44.2 1.0 CA A:ALA245 4.6 42.1 1.0 C A:SER79 4.6 46.8 1.0 N A:ASP82 4.6 50.3 1.0 O A:LEU100 4.6 49.2 1.0 C A:ASP82 4.6 50.0 1.0 O A:VAL80 4.7 50.1 1.0 CB A:SER102 4.8 43.6 1.0 N A:VAL80 4.8 47.4 1.0 CA A:VAL80 4.8 49.2 1.0 C A:VAL84 4.9 45.1 1.0 CB A:SER79 4.9 43.1 1.0 CA A:ASP82 4.9 52.0 1.0 C A:ARG243 5.0 54.8 1.0

Sodium binding site 2 out of 2 in the Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of A Methionine Aminopeptidase From Mycobacterium Abscessus within 5.0Å range: probe atom residue distance (Å) B Occ B:Na266 b:47.9 occ:1.00 O B:HOH389 2.3 47.1 1.0 O B:ALA244 2.3 45.7 1.0 O B:GLN83 2.3 46.3 1.0 O B:HOH288 2.4 40.7 1.0 O B:ASN81 2.6 48.6 1.0 C B:ALA244 3.2 45.6 1.0 C B:GLN83 3.5 49.0 1.0 C B:ASN81 3.6 49.6 1.0 N B:ALA244 3.8 50.0 1.0 CA B:ALA244 3.8 47.4 1.0 CB B:ALA244 3.8 46.5 1.0 N B:ASN81 3.9 50.9 1.0 OG B:SER102 3.9 45.5 1.0 CA B:ASN81 4.1 50.2 1.0 O B:SER79 4.2 47.8 1.0 N B:ALA245 4.2 43.4 1.0 C B:VAL80 4.2 49.5 1.0 CA B:VAL84 4.3 44.6 1.0 N B:GLN83 4.3 49.9 1.0 N B:VAL84 4.4 46.3 1.0 CA B:GLN83 4.5 50.4 1.0 O B:VAL84 4.5 44.5 1.0 CA B:ALA245 4.5 42.0 1.0 O B:VAL80 4.6 49.2 1.0 C B:SER79 4.6 47.5 1.0 O B:LEU100 4.6 49.9 1.0 N B:ASP82 4.6 50.4 1.0 C B:ASP82 4.6 49.7 1.0 CB B:SER102 4.8 44.8 1.0 N B:VAL80 4.8 47.5 1.0 CB B:SER79 4.8 44.7 1.0 CA B:VAL80 4.9 49.3 1.0 C B:VAL84 4.9 44.9 1.0 CA B:ASP82 4.9 51.1 1.0

L.Baugh, I.Phan, D.W.Begley, M.C.Clifton, B.Armour, D.M.Dranow, B.M.Taylor, M.M.Muruthi, J.Abendroth, J.W.Fairman, D.Fox, S.H.Dieterich, B.L.Staker, A.S.Gardberg, R.Choi, S.N.Hewitt, A.J.Napuli, J.Myers, L.K.Barrett, Y.Zhang, M.Ferrell, E.Mundt, K.Thompkins, N.Tran, S.Lyons-Abbott, A.Abramov, A.Sekar, D.Serbzhinskiy, D.Lorimer, G.W.Buchko, R.Stacy, L.J.Stewart, T.E.Edwards, W.C.Van Voorhis, P.J.Myler. Increasing the Structural Coverage of Tuberculosis Drug Targets. Tuberculosis (Edinb) V. 95 142 2015.
ISSN: ISSN 1472-9792
PubMed: 25613812
DOI: 10.1016/J.TUBE.2014.12.003