Sodium in PDB 3syo: Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium

The structure of Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium, PDB code: 3syo was solved by M.R.Whorton, R.Mackinnon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.68 / 3.54
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	85.737, 85.737, 178.602, 90.00, 90.00, 90.00
R / Rfree (%)	26 / 27.3

The structure of Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium also contains other interesting chemical elements:

Potassium

(K)

6 atoms

The binding sites of Sodium atom in the Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium (pdb code 3syo). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium, PDB code: 3syo:

Sodium binding site 1 out of 1 in the Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the G Protein-Gated Inward Rectifier K+ Channel GIRK2 (KIR3.2) in Complex with Sodium within 5.0Å range: probe atom residue distance (Å) B Occ A:Na601 b:84.3 occ:1.00 OD2 A:ASP228 2.5 91.6 1.0 O A:SER232 2.9 0.1 1.0 O A:ARG230 3.2 99.0 1.0 CG A:ASP228 3.6 91.0 1.0 O A:LEU275 3.7 85.5 1.0 C A:SER232 3.8 0.8 1.0 O A:ASN231 3.9 0.2 1.0 CB A:ASP228 3.9 89.2 1.0 O A:VAL276 4.1 88.5 1.0 C A:ASN231 4.1 0.7 1.0 CA A:VAL276 4.2 87.5 1.0 CA A:HIS233 4.3 99.0 1.0 C A:ARG230 4.4 0.4 1.0 N A:HIS233 4.4 0.5 1.0 O A:ASP228 4.5 93.0 1.0 N A:SER232 4.6 0.8 1.0 C A:VAL276 4.6 88.0 1.0 CA A:ASN231 4.6 0.5 1.0 ND1 A:HIS233 4.6 0.1 1.0 C A:LEU275 4.6 85.1 1.0 OD1 A:ASP228 4.7 92.2 1.0 NH2 A:ARG201 4.8 0.3 1.0 CA A:SER232 4.8 0.4 1.0 N A:VAL276 4.9 85.9 1.0 N A:ASN231 5.0 0.7 1.0 CG A:HIS233 5.0 0.1 1.0 CG1 A:VAL276 5.0 91.0 1.0 CE1 A:HIS233 5.0 0.1 1.0

M.R.Whorton, R.Mackinnon. Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation By G Proteins, Pip(2), and Sodium. Cell(Cambridge,Mass.) V. 147 199 2011.
ISSN: ISSN 0092-8674
PubMed: 21962516
DOI: 10.1016/J.CELL.2011.07.046