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Atomistry » Sodium » PDB 3rnx-3si4 » 3s54 » |
Sodium in PDB 3s54: Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212Enzymatic activity of Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212
All present enzymatic activity of Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212:
3.4.23.16; Protein crystallography data
The structure of Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212, PDB code: 3s54
was solved by
Y.-F.Tie,
Y.-F.Wang,
I.T.Weber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3s54:
The structure of Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212 also contains other interesting chemical elements:
Sodium Binding Sites:
The binding sites of Sodium atom in the Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212
(pdb code 3s54). This binding sites where shown within
5.0 Angstroms radius around Sodium atom.
In total only one binding site of Sodium was determined in the Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212, PDB code: 3s54: Sodium binding site 1 out of 1 in 3s54Go back to Sodium Binding Sites List in 3s54
Sodium binding site 1 out
of 1 in the Hiv-1 Protease Triple Mutants V32I, I47V, V82I with Antiviral Drug Darunavir in Space Group P21212
Mono view Stereo pair view
Reference:
Y.Tie,
Y.F.Wang,
P.I.Boross,
T.Y.Chiu,
A.K.Ghosh,
J.Tozser,
J.M.Louis,
R.W.Harrison,
I.T.Weber.
Critical Differences in Hiv-1 and Hiv-2 Protease Specificity For Clinical Inhibitors. Protein Sci. V. 21 339 2012.
Page generated: Tue Dec 15 06:24:22 2020
ISSN: ISSN 0961-8368 PubMed: 22238126 DOI: 10.1002/PRO.2019 |
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