Sodium in PDB 3k6n: Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain

The structure of Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain, PDB code: 3k6n was solved by Y.Xu, H.G.Shin, S.Szep, Z.Lu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 2.00
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	77.455, 77.455, 86.723, 90.00, 90.00, 90.00
R / Rfree (%)	25.4 / 26.6

The binding sites of Sodium atom in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain (pdb code 3k6n). This binding sites where shown within 5.0 Angstroms radius around Sodium atom.
In total 5 binding sites of Sodium where determined in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain, PDB code: 3k6n:
Jump to Sodium binding site number: 1; 2; 3; 4; 5;

Sodium binding site 1 out of 5 in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 1 of Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Na7 b:90.0 occ:0.25 O A:HOH529 3.6 78.6 1.0

Sodium binding site 2 out of 5 in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 2 of Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Na8 b:78.9 occ:0.25 O A:HOH510 2.7 69.2 1.0 OE2 A:GLU225 4.1 74.8 1.0 OE1 A:GLU225 4.1 75.0 1.0 CD A:GLU225 4.5 74.1 1.0 O A:HOH526 4.8 80.1 1.0

Sodium binding site 3 out of 5 in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 3 of Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Na9 b:69.0 occ:0.25 O A:HOH511 3.4 73.7 1.0 O A:HOH512 3.6 76.4 1.0

Sodium binding site 4 out of 5 in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 4 of Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Na10 b:81.9 occ:0.25 CZ A:PHE255 4.8 50.4 1.0 NA A:NA11 4.9 81.4 0.2

Sodium binding site 5 out of 5 in the Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain


Mono view


Stereo pair view

A full contact list of Sodium with other atoms in the Na binding site number 5 of Crystal Structure of the S225E Mutant KIR3.1 Cytoplasmic Pore Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Na11 b:81.4 occ:0.25 O A:HOH513 3.4 78.9 1.0 O A:HOH514 3.9 69.4 1.0 NA A:NA10 4.9 81.9 0.2

Y.Xu, H.G.Shin, S.Szep, Z.Lu. Physical Determinants of Strong Voltage Sensitivity of K(+) Channel Block. Nat.Struct.Mol.Biol. V. 16 1252 2009.
ISSN: ISSN 1545-9993
PubMed: 19915587
DOI: 10.1038/NSMB.1717